Angiogenic inhibitor pre‐administration improves the therapeutic effects of immunotherapy
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5696
Abstract: In lung cancer, immune checkpoint inhibitors (ICIs) are often inadequate for tumor growth inhibition. Angiogenic inhibitors (AIs) are required to normalize tumor vasculature for improved immune cell infiltration. However, in clinical practice, ICIs and cytotoxic… read more here.
Keywords: lung cancer; administration; cell infiltration; pre administration ... See more keywords
T‐cell infiltration and clonality correlate with programmed cell death protein 1 and programmed death‐ligand 1 expression in patients with soft tissue sarcomas
Sign Up to like & getrecommendations! Published in 2017 at "Cancer"
DOI: 10.1002/cncr.30726
Abstract: Patients with metastatic sarcomas have poor outcomes and although the disease may be amenable to immunotherapies, information regarding the immunologic profiles of soft tissue sarcoma (STS) subtypes is limited. read more here.
Keywords: infiltration clonality; death; soft tissue; cell infiltration ... See more keywords
Monocarboxylate transporter 4 inhibition potentiates hepatocellular carcinoma immunotherapy through enhancing T cell infiltration and immune attack
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32348
Abstract: Background and Aims: Monocarboxylate transporter (MCT) 4 is a high‐affinity lactate transporter that is primarily involved in the maintenance of intracellular pH homeostasis and highly expressed in different tumors. However, the role of MCT4 in… read more here.
Keywords: inhibition; cell infiltration; transporter; monocarboxylate transporter ... See more keywords
Chemoimmunotherapy with doxorubicin and caffeine combination enhanced ICD induction and T‐cell infiltration in B16F10 melanoma tumors
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23327
Abstract: Majority of chemotherapeutic agents can elicit antitumor immunity and modulate the composition, density, function, and distribution of tumor infiltrating lymphocytes (TILs), to influence differential therapeutic responses and prognosis in cancer patients. The clinical success of… read more here.
Keywords: icd induction; cell; cell infiltration; combination ... See more keywords
Quantitative histopathologic assessment of perfusion MRI as a marker of glioblastoma cell infiltration in and beyond the peritumoral edema region
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.26580
Abstract: Conventional MRI fails to detect regions of glioblastoma cell infiltration beyond the contrast‐enhanced T1 solid tumor region, with infiltrating tumor cells often migrating along host blood vessels. read more here.
Keywords: cell infiltration; glioblastoma cell; mri; infiltration beyond ... See more keywords
Circulating PD-L1 is associated with T cell infiltration and predicts prognosis in patients with CRLM following hepatic resection
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-03021-3
Abstract: Exosomal PD-L1 (exoPD-L1) could induce immunosuppression functionally, thus impairing patients’ survival in melanoma, NSCLC, and gastric cancer. However, no evidence demonstrates the feasibility of circulating exoPD-L1 and soluble PD-L1 (sPD-L1) as biomarkers for prognosis and… read more here.
Keywords: cell infiltration; exopd spd; spd;
Construction of an N6-methyladenosine lncRNA- and immune cell infiltration-related prognostic model in colorectal cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Protoplasma"
DOI: 10.1007/s00709-021-01718-x
Abstract: The present paper aims to shed light on the influence of N6-methyladenosine (m6A) long non-coding RNAs (lncRNAs) and immune cell infiltration on colorectal cancer (CRC). We downloaded workflow-type data and xml-format clinical data on CRC… read more here.
Keywords: cell infiltration; analysis; immune cell; prognostic model ... See more keywords
Tumor-infiltrating B cell is associated with the control of progression of gastric cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Immunologic research"
DOI: 10.1007/s12026-020-09167-z
Abstract: This study aimed to further explore the clinicopathological correlation of B cell infiltration in gastric cancer (GC) and its impact on prognostic. By immunohistochemical method, CD20+ B cells, CD3+ T cells, CD66b+ tumor-associated neutrophils, CD163+… read more here.
Keywords: gastric cancer; infiltration; cox regression; cell infiltration ... See more keywords
Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer cell"
DOI: 10.1016/j.ccell.2019.05.004
Abstract: We investigated the role of chemokines in regulating T cell accumulation in solid tumors. CCL5 and CXCL9 overexpression was associated with CD8+ T cell infiltration in solid tumors. T cell infiltration required tumor cell-derived CCL5 and was amplified… read more here.
Keywords: solid tumors; cell infiltration; ccl5 expression; cell ... See more keywords
Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.07.035
Abstract: Antoni Ribas,* Reinhard Dummer, Igor Puzanov, Ari VanderWalde, Robert H.I. Andtbacka, Olivier Michielin, Anthony J. Olszanski, Josep Malvehy, Jonathan Cebon, Eugenio Fernandez, John M. Kirkwood, Thomas F. Gajewski, Lisa Chen, Kevin S. Gorski, AbrahamA. Anderson,… read more here.
Keywords: promotes intratumoral; virotherapy promotes; cell infiltration; intratumoral cell ... See more keywords
Tumor Cell‐Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy
Sign Up to like & getrecommendations! Published in 2018 at "Immunity"
DOI: 10.1016/j.immuni.2018.06.006
Abstract: Summary The biological and functional heterogeneity between tumors—both across and within cancer types—poses a challenge for immunotherapy. To understand the factors underlying tumor immune heterogeneity and immunotherapy sensitivity, we established a library of congenic tumor… read more here.
Keywords: cell intrinsic; cell infiltration; tumor cell; cell ... See more keywords