Treatment of type 1 diabetes by regulatory T‐cell infusion via regulating the expression of inflammatory cytokines
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DOI: 10.1002/jcb.27875
Abstract: To explore the role and molecular mechanism of regulatory T (Treg) cells in type 1 diabetes (T1D). read more here.
Keywords: treatment type; regulatory cell; diabetes regulatory; type diabetes ... See more keywords
Clofarabine for Lymphodepletion Before CAR-T-Cell Infusion: A Brief Case Report
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000002668
Abstract: Given the shortage of fludarabine, alternative preparative lymphodepleting regimens for CAR-T-cell therapy need to be identified. We present a case of relapsed/refractory B-cell acute lymphoblastic leukemia requiring multiple lines of salvage therapy with persistent extensive… read more here.
Keywords: cell; clofarabine; case; car cell ... See more keywords
Hematopoietic cell infusion‐related adverse events in pediatric/small recipients in a prospective/multicenter study
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DOI: 10.1111/trf.15786
Abstract: Hematopoietic cell infusion‐related adverse events (HCI‐AEs) in hematopoietic stem cell transplantations (HSCTs) have been largely attributed to toxicity of dimethyl sulfoxide (DMSO) for cryopreservation, but HSC products also contain various cells and plasma components. Our… read more here.
Keywords: adverse events; infusion related; hematopoietic cell; related adverse ... See more keywords
Comparison of cryoprotectants in hematopoietic cell infusion–related adverse events
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DOI: 10.1111/trf.16877
Abstract: The standard cryoprotectant for human cellular products is dimethyl sulfoxide (DMSO), which is associated with hematopoietic cell infusion‐related adverse events (HCI‐AEs) in hematopoietic stem cell transplantation including peripheral blood stem cell (PBSC) transplantation (PBSCT). DMSO… read more here.
Keywords: cell; infusion related; related adverse; hematopoietic cell ... See more keywords
Autologous Hematopoietic Stem Cell Infusion for Myelosuppression after Bcma-CART Therapy in Relapsed Myeloma Patients
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DOI: 10.1182/blood-2019-128410
Abstract: Abstract Background: The adoption of B cell mature antigen (BCMA) targeted chimeric antigen receptor (CAR) T cells is demonstrating promise prospects in refractory relapsed multiple myeloma (RRMM), however the persistent severe myelosuppression remains a serious… read more here.
Keywords: myelosuppression; infusion; stem cell; cell infusion ... See more keywords
Phase I Trial of Prophylactic Donor-Derived IL-2-Activated NK Cell Infusion after Allogeneic Hematopoietic Stem Cell Transplantation from a Matched Sibling Donor
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13112673
Abstract: Simple Summary Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative option for high-risk hematologic malignancies. However, disease recurrence after allo-HSCT remains a critical issue, underlining the need to develop maintenance therapy. In this context,… read more here.
Keywords: allo hsct; donor derived; donor; cell infusion ... See more keywords