Tuning the Local Availability of VEGF within Glycosaminoglycan‐Based Hydrogels to Modulate Vascular Endothelial Cell Morphogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202000068
Abstract: Incorporation of sulfated glycosaminoglycans (GAGs) into cell‐instructive polymer networks is shown to be instrumental in controlling the diffusivity and activity of growth factors. However, a subtle balance between local retention and release of the factors… read more here.
Keywords: sulfation pattern; cell instructive; vascular endothelial; local availability ... See more keywords
Assembly of PEG Microgels into Porous Cell‐Instructive 3D Scaffolds via Thiol‐Ene Click Chemistry
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201800160
Abstract: The assembly of microgel building blocks into 3D scaffolds is an emerging strategy for tissue engineering. A key advantage is that the inherent microporosity of these scaffolds provides cells with a more permissive environment than… read more here.
Keywords: chemistry; thiol ene; ene click; instructive scaffolds ... See more keywords
Multifunctional Coatings and Nanotopographies: Toward Cell Instructive and Antibacterial Implants
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201801103
Abstract: In biomaterials science, it is nowadays well accepted that improving the biointegration of dental and orthopedic implants with surrounding tissues is a major goal. However, implant surfaces that support osteointegration may also favor colonization of… read more here.
Keywords: multifunctional coatings; nanotopographies toward; coatings nanotopographies; cell instructive ... See more keywords
Microparticles Decorated with Cell-Instructive Surface Chemistries Actively Promote Wound Healing.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced materials"
DOI: 10.1002/adma.202208364
Abstract: Wound healing is a complex biological process involving close crosstalk between various cell types. Dysregulation in any of these processes, such as in diabetic wounds, results in chronic non-healing wounds. Fibroblasts are a critical cell… read more here.
Keywords: cell instructive; wound healing; surface chemistries; instructive surface ... See more keywords
Cell-instructive starPEG-heparin-collagen composite matrices.
Sign Up to like & getrecommendations! Published in 2017 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2017.01.086
Abstract: Polymer hydrogels can be readily modulated with regard to their physical properties and functionalized to recapitulate molecular cues of the extracellular matrix (ECM). However, they remain structurally different from the hierarchical supramolecular assemblies of natural… read more here.
Keywords: collagen; heparin collagen; instructive starpeg; cell instructive ... See more keywords
Cell instructive Liquid Crystalline Networks for myotube formation
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.103077
Abstract: Summary Development of biological tissues in vitro is not a trivial task and requires the correct maturation of the selected cell line. To this aim, many attempts were done mainly by mimicking the biological environment… read more here.
Keywords: instructive liquid; crystalline networks; liquid crystalline; cell instructive ... See more keywords
Cell-Instructive Alginate Hydrogels Targeting RhoA.
Sign Up to like & getrecommendations! Published in 2018 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.8b00436
Abstract: Cellular processes involve dynamic rearrangement of the cytoskeleton. The GTPase RhoA plays a fundamental role in controlling cytoskeletal architecture. The phenotypic stability of chondrocytes is enhanced through inhibition of RhoA, whereas RhoA activation leads to… read more here.
Keywords: alginate; rhoa; alginate hydrogels; hydrogels targeting ... See more keywords
Cell-instructive high-resolution micropatterned polylactic acid surfaces.
Sign Up to like & getrecommendations! Published in 2017 at "Biofabrication"
DOI: 10.1088/1758-5090/aa7d24
Abstract: Micro and nanoscale topographical structuring of biomaterial surfaces has been a valuable tool for influencing cell behavior, including cell attachment, proliferation and differentiation. However, most fabrication techniques for surface patterning of implantable biomaterials suffer from… read more here.
Keywords: resolution; high resolution; polylactic acid; cell instructive ... See more keywords
3D bioassembly of cell-instructive chondrogenic and osteogenic hydrogel microspheres containing allogeneic stem cells for hybrid biofabrication of osteochondral constructs.
Sign Up to like & getrecommendations! Published in 2022 at "Biofabrication"
DOI: 10.1088/1758-5090/ac61a3
Abstract: Recently developed modular bioassembly techniques hold tremendous potential in tissue engineering and regenerative medicine, due to their ability to recreate the complex microarchitecture of native tissue. Here, we developed a novel approach to fabricate hybrid… read more here.
Keywords: cell instructive; tissue; chondrogenic osteogenic; instructive chondrogenic ... See more keywords