Tropolone‐Conjugated DNA: A Fluorescent Thymidine Analogue Exhibits Solvatochromism, Enzymatic Incorporation into DNA and HeLa Cell Internalization
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200732
Abstract: Tropolone is a non‐benzenoid aromatic scaffold with unique photophysical and metal‐chelating properties. Recently, it has been conjugated with DNA, and the photophysical properties of this conjugate have been explored. Tropolonyl‐deoxyuridine (tr‐dU) is a synthetic fluorescent… read more here.
Keywords: enzymatic incorporation; conjugated dna; dna; analogue exhibits ... See more keywords
Cooperative Strategies for Enhancing Performance of Photothermal Therapy (PTT) Agent: Optimizing Its Photothermal Conversion and Cell Internalization Ability.
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DOI: 10.1002/smll.201603275
Abstract: Photothermal conversion ability (PCA) and cell internalization ability (CIA) are two key factors for determining the performance of photothermal agents. The previous studies mostly focus on improving the PCA by exploring new photothermal nanomaterials. Herein,… read more here.
Keywords: photothermal conversion; cell internalization; performance; ptt ... See more keywords
Antigen-presenting cell internalization is key for understanding and evaluating therapeutic antibodies’ immunogenicity
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1617395
Abstract: Therapeutic antibodies have revolutionized the treatment of many diseases. However, their safety and efficacy are often altered by their immunogenicity, as many patients frequently develop anti-drug antibodies. Dendritic cells (DCs) are the most potent antigen-presenting… read more here.
Keywords: therapeutic antibodies; cell internalization; presenting cell; immunogenicity ... See more keywords