Septin and Actin Contributions to Endothelial Cell-cell Junctions and Monolayer Integrity.
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DOI: 10.1002/cm.21732
Abstract: Septins in endothelial cells (ECs) have important roles supporting the integrity of the endothelial monolayer. Cell-cell junctions in EC monolayers are highly dynamic, with continuous retractions and protrusions. Depletion of septins in ECs leads to… read more here.
Keywords: cell; cell junctions; membrane; integrity ... See more keywords
ADAM9 is present at endothelial cell - cell junctions and regulates monocyte – endothelial transmigration
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and Biophysical Research Communications"
DOI: 10.1016/j.bbrc.2017.09.089
Abstract: We have found that A Disintegrin And Metalloproteinase-9 (ADAM9) localises to cell-cell junctions with VE-Cadherin in confluent endothelial monolayers. Co-cultures of cells separately transfected with ADAM9-EGFP or ADAM9-HA showed expression is required in two adjacent… read more here.
Keywords: adam9; cell junctions; cell; endothelial transmigration ... See more keywords
Tyrosine-Based Signals Regulate the Assembly of Daple⋅PARD3 Complex at Cell-Cell Junctions
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DOI: 10.1016/j.isci.2020.100859
Abstract: Summary Polarized distribution of organelles and molecules inside a cell is vital for a range of cellular processes and its loss is frequently encountered in disease. Polarization during planar cell migration is a special condition… read more here.
Keywords: cell junctions; cell; tyrosine based; based signals ... See more keywords
HIV-1 exposure triggers autophagic degradation of stathmin and hyperstabilization of microtubules to disrupt epithelial cell junctions
Sign Up to like & getrecommendations! Published in 2020 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-020-0175-1
Abstract: Dear Editor, Human immunodeficiency virus type 1 (HIV-1) infection is mainly initiated on mucosal epithelial surfaces. Exposure to HIV-1 impairs the mucosal epithelial barrier, allowing viral transmission across the mucosal epithelium. Interaction of HIV-1 envelope… read more here.
Keywords: data fig; cell junctions; supplementary data; gp120 ... See more keywords
Integrin-dependent regulation of the endothelial barrier
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DOI: 10.1080/21688370.2019.1685844
Abstract: ABSTRACT The endothelium physically separates blood from surrounding tissue and yet allows for the regulated passage of nutrients, waste, and leukocytes into and out of the circulation. Trans-endothelium flux occurs across endothelial cells (transcellular) and… read more here.
Keywords: cell junctions; cell; endothelial barrier; cell cell ... See more keywords
Preferential recruitment and stabilization of Myosin II at compartment boundaries in Drosophila
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cell Science"
DOI: 10.1242/jcs.260447
Abstract: ABSTRACT The regulation of mechanical tension exerted at cell junctions guides cell behavior during tissue formation and homeostasis. Cell junctions along compartment boundaries, which are lineage restrictions separating cells with different fates and functions within… read more here.
Keywords: cell junctions; cell; mechanical tension; compartment boundaries ... See more keywords
Zyxin contributes to coupling between cell junctions and contractile actomyosin networks during apical constriction
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DOI: 10.1371/journal.pgen.1010319
Abstract: One of the most common cell shape changes driving morphogenesis in diverse animals is the constriction of the apical cell surface. Apical constriction depends on contraction of an actomyosin network in the apical cell cortex,… read more here.
Keywords: cell; apical constriction; actomyosin networks; cell junctions ... See more keywords
CFTR, Cell Junctions and the Cytoskeleton
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23052688
Abstract: The multi-organ disease cystic fibrosis (CF) is caused by mutations in the gene encoding the CF transmembrane conductance regulator (CFTR) protein, a cAMP regulated chloride (Cl−) and bicarbonate (HCO3−) ion channel expressed at the apical… read more here.
Keywords: cell junctions; cell; junctions cytoskeleton; cftr cell ... See more keywords