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Published in 2020 at "Nature"
DOI: 10.1038/s41586-020-2157-4
Abstract: Single-cell analysis is a valuable tool for dissecting cellular heterogeneity in complex systems 1 . However, a comprehensive single-cell atlas has not been achieved for humans. Here we use single-cell mRNA sequencing to determine the…
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Keywords:
single cell;
construction human;
human cell;
cell ... See more keywords
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1
Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2043662
Abstract: ABSTRACT The tumor microenvironment (TME) profoundly influences tumor progression and affects immunotherapy responses and resistance. Understanding its heterogeneity is the key for developing immunotherapy. However, the available methods can only partially portray the TME heterogeneity…
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Keywords:
rna seq;
cell;
tumor;
cell landscape ... See more keywords
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2
Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac633
Abstract: Abstract Individual cells are basic units of life. Despite extensive efforts to characterize the cellular heterogeneity of different organisms, cross-species comparisons of landscape dynamics have not been achieved. Here, we applied single-cell RNA sequencing (scRNA-seq)…
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Keywords:
species cell;
cross species;
cell landscape;
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Published in 2023 at "Research"
DOI: 10.34133/research.0025
Abstract: Newborn ruminants are considered functionally monogastric animals. The poor understanding of cellular differences between newborn and mature ruminants prevents the improvement of health and performance of domestic ruminants. Here, we performed the single-cell RNA sequencing…
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Keywords:
cell;
age microbiota;
microbiota dependent;
plasticity ... See more keywords