Moxetumomab Pasudotox: First Global Approval
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DOI: 10.1007/s40265-018-1000-9
Abstract: Moxetumomab pasudotox-tdfk (LUMOXITI™), an anti CD22 recombinant immunotoxin, has been developed by MedImmune and its parent company AstraZeneca for the treatment of hairy cell leukaemia. The product, discovered at the National Cancer Institute, is an… read more here.
Keywords: pasudotox; approval; cell leukaemia; moxetumomab pasudotox ... See more keywords
Systemic mastocytosis and probable mast cell leukaemia in a koala (Phascolarctos cinereus).
Sign Up to like & getrecommendations! Published in 2020 at "Australian veterinary journal"
DOI: 10.1111/avj.12904
Abstract: BACKGROUND To the authors' knowledge, this is the first report of mast cell neoplasia in a koala (Phascolarctos cinereus). CASE REPORT An adult female koala was presented for rapidly deteriorating health and death of a… read more here.
Keywords: cell leukaemia; mast; systemic mastocytosis; mast cell ... See more keywords
The role of CD28 in adult T‐cell leukaemia/lymphoma
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DOI: 10.1111/bjh.17214
Abstract: T-cell-specific surface glycoprotein CD28 belongs to the subfamily of costimulatory molecules characterized by an extracellular immunoglobulin variable-like domain. Other members of the subfamily include inducible T-cell costimulator (ICOS), cytotoxic T-lymphocyte-associated antigen 4 (CTLA4), programmed cell… read more here.
Keywords: icos; cell leukaemia; cd28; ctla4 ... See more keywords
Morphological and immunophenotypical features of hairy cell leukaemia involving lymph nodes and extranodal tissues
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DOI: 10.1111/his.13206
Abstract: Hairy cell leukaemia (HCL) is a rare B cell neoplasm that mainly affects bone marrow (BM), peripheral blood (PB) and spleen. Involvement of lymph nodes and extranodal structures is considered infrequent. Herein we describe our… read more here.
Keywords: cell; cell leukaemia; lymph nodes; hairy cell ... See more keywords
Aggressive natural killer (NK)‐cell leukaemia and extranodal NK/T‐cell lymphoma are two distinct diseases that differ in their clinical presentation and cytogenetic findings
Sign Up to like & getrecommendations! Published in 2018 at "Histopathology"
DOI: 10.1111/his.13463
Abstract: Aggressive natural killer (NK)‐cell leukaemia (ANKCL) and extranodal NK/T‐cell lymphoma (ENKTCL) with secondary bone marrow involvement are rare bone marrow NK/T‐cell neoplasms and share similar features. This study aimed to distinguish these two entities. read more here.
Keywords: killer cell; cell leukaemia; natural killer; extranodal cell ... See more keywords
A novel canine B‐cell leukaemia cell line. Establishment, characterisation and sensitivity to chemotherapeutics
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary and Comparative Oncology"
DOI: 10.1111/vco.12257
Abstract: We established a new B-cell leukaemia cell line CLB70 from a dog with chronic lymphocytic leukaemia. This cell line is positive for CD20, CD45, CD79a, MHC class II, IgG, IgM; weakly positive for CD21; and… read more here.
Keywords: cell line; cell leukaemia; line; leukaemia cell ... See more keywords
Primary plasma cell leukaemia in a 39-year-old man
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DOI: 10.1136/bcr-2020-235543
Abstract: Plasma cell leukaemia (PCL) is an aggressive haematological malignancy which is classified into primary (pPCL) and secondary PCL. A 39-year-old Indian man presented to the Department of Hematology with a 2-week history of fever and… read more here.
Keywords: cell leukaemia; year; plasma cell; man ... See more keywords
Human T-cell leukaemia virus type 1 and Adult T-cell leukaemia/lymphoma in Queensland, Australia: a retrospective cross-sectional study
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DOI: 10.1136/sextrans-2021-055241
Abstract: Objectives Human T-cell leukaemia virus type 1 (HTLV-1), an STI, is reported to be highly prevalent in Indigenous communities in Central Australia. HTLV-1 is an incurable, chronic infection which can cause Adult T-cell leukaemia/lymphoma (ATL).… read more here.
Keywords: cell leukaemia; cell; atl; queensland ... See more keywords
A Qualitative Study Exploring Perceptions to the Human T Cell Leukaemia Virus Type 1 in Central Australia: Barriers to Preventing Transmission in a Remote Aboriginal Population
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.845594
Abstract: Background Central Australia has the highest recorded prevalence of infection with the human T cell leukaemia virus type 1 (HTLV-1) worldwide. Each of the clinical diseases associated with HTLV-1 have been reported in this region,… read more here.
Keywords: cell leukaemia; htlv; transmission; central australia ... See more keywords
The Genomics of Hairy Cell Leukaemia and Splenic Diffuse Red Pulp Lymphoma
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DOI: 10.3390/cancers14030697
Abstract: Simple Summary Hairy cell leukaemia is a rare chronic lymphoid malignancy with distinctive clinical and laboratory features which include an enlarged spleen, low blood counts, and infiltration of the spleen and bone marrow, with lymphocytes… read more here.
Keywords: cell leukaemia; splenic diffuse; cell; hairy cell ... See more keywords