Corneal Endothelial Cell Loss 3 Years After Successful Descemet Stripping Automated Endothelial Keratoplasty in the Cornea Preservation Time Study: A Randomized Clinical Trial
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Ophthalmology"
DOI: 10.1001/jamaophthalmol.2017.4970
Abstract: Importance Demonstrating that endothelial cell loss following Descemet stripping automated endothelial keratoplasty (DSAEK) is independent of donor cornea preservation time (PT) could increase the pool of corneal tissue available for keratoplasty. Objective To determine whether… read more here.
Keywords: cornea preservation; cell loss; endothelial cell; study ... See more keywords
Chronic resveratrol administration reduces oxidative stress and brain cell loss and improves memory of recognition in old rats
Sign Up to like & getrecommendations! Published in 2023 at "Synapse"
DOI: 10.1002/syn.22271
Abstract: The cognitive functions of people over 60 years of age have been diminished, due to the structural and functional changes that the brain has during aging. The most evident changes are at the behavioral and… read more here.
Keywords: recognition; cell loss; rsvl; oxidative stress ... See more keywords
Long-term endothelial cell loss with the iris-claw intraocular phakic lenses (Artisan®)
Sign Up to like & getrecommendations! Published in 2019 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-019-04506-9
Abstract: To evaluate the endothelial cell loss in patients with iris-claw phakic lenses (Artisan®) in a long-term follow-up. We analyzed the medical records of patients who had undergone iris-claw phakic lens implantation and who had at… read more here.
Keywords: iris claw; cell loss; endothelial cell; phakic ... See more keywords
Inhibition of GSK-3β Activation Protects SD Rat Retina Against N-Methyl-N-Nitrosourea-Induced Degeneration by Modulating the Wnt/β-Catenin Signaling Pathway
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-017-0973-2
Abstract: Retinal degenerative diseases are characterized by photoreceptor cell loss. Photoreceptor cell loss leading to retinal degeneration can be induced by N-methyl-N-nitrosourea (MNU), which was widely used to mimic the pathology. However, the mechanism by which… read more here.
Keywords: photoreceptor cell; degeneration; gsk; cell loss ... See more keywords
Parameters associated with endothelial cell density variability after Descemet membrane endothelial keratoplasty.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2019.10.017
Abstract: PURPOSE To evaluate which parameters may affect endothelial cell loss after Descemet membrane endothelial keratoplasty (DMEK) by comparing eyes in the low versus high quartile of endothelial cell loss over a follow-up period of four… read more here.
Keywords: cell loss; endothelial cell; group; cell ... See more keywords
Endothelial cell loss 5 years after Preserflo MicroShunt implantation: About two cases
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Ophthalmology Case Reports"
DOI: 10.1016/j.ajoc.2021.101238
Abstract: Purpose Preserflo MicroShunt is a minimally-invasive glaucoma drainage micro-tube used to shunt aqueous humor from the anterior chamber to the subtenon space. The safety of the procedure was considered satisfactory with a majority of minor… read more here.
Keywords: preserflo microshunt; endothelial cell; cell; cell loss ... See more keywords
In vivo assay of the ethanol-induced embryonic hair cell loss and the protective role of the retinoic and folic acid in zebrafish larvae (Danio rerio).
Sign Up to like & getrecommendations! Published in 2019 at "Alcohol"
DOI: 10.1016/j.alcohol.2018.07.008
Abstract: In reference to the auditory manifestation of fetal alcohol syndrome, previous work has preferentially focused on the deviant neural development of the auditory system. Changes in the sensory hair cell, the ultimate sensory organ, were… read more here.
Keywords: folic acid; hair cell; hair; cell loss ... See more keywords
Cisplatin-induced hair cell loss in zebrafish neuromasts is accompanied by protein nitration and Lmo4 degradation.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2020.115342
Abstract: Generation of reactive oxygen species, a critical factor in cisplatin-induced ototoxicity, leads to the formation of peroxynitrite, which in turn results in the nitration of susceptible proteins. Previous studies indicated that LMO4, a transcriptional regulator,… read more here.
Keywords: nitration; hair cell; cell loss; hair ... See more keywords
Tamoxifen offers long-term neuroprotection after hippocampal silent infarct in male rats
Sign Up to like & getrecommendations! Published in 2021 at "Hormones and Behavior"
DOI: 10.1016/j.yhbeh.2021.105085
Abstract: Silent infarcts (SI) are a cerebral small vessel disease characterized by small subcortical infarcts. These occur in the absence of typical ischemia symptoms but are linked to cognitive decline and dementia. While there are no… read more here.
Keywords: tamoxifen offers; long term; cell loss; apoptosis gliosis ... See more keywords
Enhancing calmodulin binding to ryanodine receptor is crucial to limit neuronal cell loss in Alzheimer disease
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-86822-x
Abstract: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive neuronal cell loss. Recently, dysregulation of intracellular Ca2+ homeostasis has been suggested as a common proximal cause of neural dysfunction in AD. Here, we investigated… read more here.
Keywords: alzheimer disease; neuronal cell; cell loss; ryanodine receptor ... See more keywords
ACBP/DBI protein neutralization confers autophagy-dependent organ protection through inhibition of cell loss, inflammation, and fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2207344119
Abstract: Significance Pharmacological induction of autophagy usually involves small molecules targeting intracellular signaling cascades. Here, Motiño et al. demonstrate that monoclonal antibody–mediated neutralization of an extracellular inhibitor of autophagy, acyl-coenzyme A binding protein (ACBP)/diazepam-binding inhibitor (DBI),… read more here.
Keywords: cell loss; dbi; loss inflammation; inflammation fibrosis ... See more keywords