Association of Twice-Daily Radiotherapy With Subsequent Brain Metastases in Adults With Small Cell Lung Cancer
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DOI: 10.1001/jamanetworkopen.2019.0103
Abstract: Importance Although thoracic twice-daily radiotherapy (TDRT) is one of the standards of care for small cell lung cancer, its association with brain metastases remains unknown. Objective To investigate the association of TDRT vs once-daily radiotherapy… read more here.
Keywords: brain metastases; group; cell lung; lung cancer ... See more keywords
Trends in Prices of Drugs Used to Treat Metastatic Non–Small Cell Lung Cancer in the US From 2015 to 2020
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DOI: 10.1001/jamanetworkopen.2021.44923
Abstract: This cross-sectional study examines trends in costs of brand-name medications for treatment of non–small cell lung cancer and within-class price differences between these medications in the US from 2015 to 2020. read more here.
Keywords: lung cancer; non small; small cell; 2015 2020 ... See more keywords
Comparison of Carboplatin With Cisplatin in Small Cell Lung Cancer in US Veterans
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DOI: 10.1001/jamanetworkopen.2022.37699
Abstract: Key Points Question What is the platinum agent of choice in treating small cell lung cancer (SCLC), cisplatin or carboplatin? Findings In this cohort study of 4408 patients at US Veteran Affairs hospitals, there was… read more here.
Keywords: lung cancer; carboplatin; small cell; carboplatin cisplatin ... See more keywords
Association of Smoking With Patient Characteristics and Outcomes in Small Cell Lung Carcinoma, 2011-2018
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DOI: 10.1001/jamanetworkopen.2022.4830
Abstract: Key Points Question Do patient characteristics of smokers and never-smokers differ among patients with small cell lung carcinoma (SCLC)? Findings In this cohort study examining 225 788 patients with lung cancer, among patients with SCLC, there… read more here.
Keywords: lung carcinoma; never smokers; characteristics outcomes; patient characteristics ... See more keywords
A Cast of Shadow on Postoperative Radiotherapy for pIIIA-N2 Non-Small Cell Lung Cancer?
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DOI: 10.1001/jamaoncol.2022.4442
Abstract: This Viewpoint discusses 2 recent randomized clinical trials evaluating the role of mediastinal postoperative radiotherapy in patients with non–small cell lung cancer. read more here.
Keywords: lung cancer; non small; postoperative radiotherapy; small cell ... See more keywords
Emerging Strategies for the Treatment of Small Cell Lung Cancer: A Review.
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DOI: 10.1001/jamaoncol.2022.5631
Abstract: Importance Small cell lung cancer (SCLC) is an aggressive disease that is characterized by rapid growth and the early development of metastases. Patients typically respond to initial chemotherapy but quickly experience relapse, resulting in a… read more here.
Keywords: lung cancer; cell; small cell; treatment ... See more keywords
Neoadjuvant Immunotherapy for Patients With Non-Small Cell Lung Cancer-Is a New Era Coming?
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DOI: 10.1001/jamaoncol.2022.6898
Abstract: The Viepoint discusses several points regarding whether there is enough data to accept neoadjuvant immunotherapy as a daily practice for patients with operable non–small cell lung cancer. read more here.
Keywords: lung cancer; non small; neoadjuvant immunotherapy; small cell ... See more keywords
Molecular Marker Testing in Curable Non-Small Cell Lung Cancer-Practice Necessarily Precedes Data.
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DOI: 10.1001/jamaoncol.2023.0251
Abstract: This Viewpoint describes the use of broad molecular marker testing in patients with early-stage non–small cell lung cancer. read more here.
Keywords: marker testing; molecular marker; lung cancer; non small ... See more keywords
Adjuvant Treatments for Surgically Resected Non-Small Cell Lung Cancer Harboring EGFR Mutations: A Review.
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DOI: 10.1001/jamaoncol.2023.0459
Abstract: Importance The use of adjuvant chemotherapy for stage IB-IIIA resected non-small cell lung cancer (NSCLC) has limited benefit for improving cure rates. The proportion of epidermal growth factor receptor (EGFR) alterations among patients with resected… read more here.
Keywords: lung cancer; non small; resected non; small cell ... See more keywords
Dynamic monitoring of PD‐L1 and Ki67 in circulating tumor cells of metastatic non‐small cell lung cancer patients treated with pembrolizumab
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DOI: 10.1002/1878-0261.13317
Abstract: Programmed cell death protein ligand‐1 (PD‐L1) expression in non‐small cell lung cancer (NSCLC) tumors guides treatment selection. PD‐L1 expression in circulating tumor cells (CTCs) may provide further information. We have explored PD‐L1 and marker of… read more here.
Keywords: cell; non small; ki67; small cell ... See more keywords
Atezolizumab and stereotactic body radiotherapy in patients with advanced non‐small cell lung cancer: safety, clinical activity and ctDNA responses—the ComIT‐1 trial
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DOI: 10.1002/1878-0261.13330
Abstract: The introduction of immune checkpoint inhibitors has transformed the treatment landscape of metastatic non‐small cell lung cancer. However, challenges remain to increase the fraction of patients achieving durable clinical responses to these drugs and to… read more here.
Keywords: small cell; lung cancer; non small; cell lung ... See more keywords