CellMarkerPipe: cell marker identification and evaluation pipeline in single cell transcriptomes
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-63492-z
Abstract: Assessing marker genes from all cell clusters can be time-consuming and lack systematic strategy. Streamlining this process through a unified computational platform that automates identification and benchmarking will greatly enhance efficiency and ensure a fair… read more here.
Keywords: cell; marker; cell marker; identification evaluation ... See more keywords
Follicular pancreatitis: Case report and literature review
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000032837
Abstract: Rationale: Follicular pancreatitis is a very rare type of focal chronic pancreatitis and is often mistaken for pancreatic neoplasms. It is histologically characterized by extensive lymphoid follicular formation with reactive germinal centers. Patient concerns: A… read more here.
Keywords: follicular pancreatitis; case report; pancreatitis case; pancreatitis ... See more keywords
Identification and Validation of NK Marker Genes in Ovarian Cancer by scRNA-seq Combined with WGCNA Algorithm
Sign Up to like & getrecommendations! Published in 2023 at "Mediators of Inflammation"
DOI: 10.1155/2023/6845701
Abstract: Background As an innate immune system effector, natural killer cells (NK cells) play a significant role in tumor immunotherapy response and clinical outcomes. Methods In our investigation, we collected ovarian cancer samples from TCGA and… read more here.
Keywords: cell; ovarian cancer; marker genes; cell marker ... See more keywords
Pediatric Astrocytomas and Their Association With Polymorphisms in Embryonic Stem Cell Marker Genes.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of child neurology"
DOI: 10.1177/08830738221091043
Abstract: BACKGROUND Embryonic stem cell markers, such as SOX2, NANOG, and OCT4, are transcription factors expressed in pluripotent stem cells, involved in the mediation of pluripotency and self-renewal. Especially after the discovery of cancer stem cells,… read more here.
Keywords: stem cell; embryonic stem; cell marker; stem ... See more keywords
Integrative analysis of single-cell and bulk RNA-sequencing data revealed T cell marker genes based molecular sub-types and a prognostic signature in lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.13070/mm.en.3.183
Abstract: Immunotherapy has emerged as a promising modality for addressing advanced or conventionally drug-resistant malignancies. When it comes to lung adenocarcinoma (LUAD), T cells have demonstrated significant influence on both antitumor activity and the tumor microenvironment.… read more here.
Keywords: cell marker; single cell; signature; cell ... See more keywords
Integrated analysis of single-cell and bulk transcriptome identifies a signature based on NK cell marker genes to predict prognosis and therapeutic response in clear cell renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Translational Cancer Research"
DOI: 10.21037/tcr-22-2782
Abstract: Background Accumulating evidence has highlighted the effects of natural killer (NK) cells on shaping anti-tumor immunity. This study aimed to construct an NK cell marker gene signature (NKMS) to predict prognosis and therapeutic response of… read more here.
Keywords: cell; ccrcc patients; analysis; single cell ... See more keywords
CD44: a cancer stem cell marker and therapeutic target in leukemia treatment
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1354992
Abstract: CD44 is a ubiquitous leukocyte adhesion molecule involved in cell-cell interaction, cell adhesion, migration, homing and differentiation. CD44 can mediate the interaction between leukemic stem cells and the surrounding extracellular matrix, thereby inducing a cascade… read more here.
Keywords: cell marker; stem cell; stem; cancer stem ... See more keywords
A novel myeloid cell marker genes related signature can indicate immune infiltration and predict prognosis of hepatocellular carcinoma: Integrated analysis of bulk and single-cell RNA sequencing
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1118377
Abstract: Myeloid cells are physiologically related to innate immunity and inflammation. Tumor-associated myeloid cells gained increasing interest because of their critical roles in tumor progression and anticancer immune responses in human malignancies. However, the associations between… read more here.
Keywords: cell; signature; myeloid cell; risk ... See more keywords
Reactive Oxygen Species Regulation of Chemoresistance and Metastatic Capacity of Melanoma: Role of the Cancer Stem Cell Marker CD271
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11041229
Abstract: BRAF mutations are present in 30–50% of cases of cutaneous melanoma, and treatment with selective BRAF and MEK inhibitors has been introduced. However, the development of resistance to these drugs often occurs. Chemo-resistant melanoma cells… read more here.
Keywords: reactive oxygen; cd271; stem cell; melanoma ... See more keywords
The role of tumor budding in colorectal adenocarcinoma: Possible involvement of the intestinal cancer stem cell marker Lgr5
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Pathology and Microbiology"
DOI: 10.4103/ijpm.ijpm_154_19
Abstract: Background: Tumor budding (TB) is a promising prognostic factor in colorectal cancer (CRC) that is independent of tumor-node-metastasis (TNM) staging. Leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5) is a stem cell marker and a member of… read more here.
Keywords: role; stem cell; cancer; tumor budding ... See more keywords