IL-36γ and IL-36Ra Reciprocally Regulate Colon Inflammation and Tumorigenesis by Modulating the Cell-Matrix Adhesion Network and Wnt Signaling.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced science"
DOI: 10.1002/advs.202103035
Abstract: Inflammatory bowel disease and colorectal cancer are associated with dysregulation of cytokine networks. However, it is challenging to target cytokines for effective intervention because of the overlapping functions and unpredictable interactions of cytokines in such… read more here.
Keywords: cell matrix; matrix adhesion; reciprocally regulate; tumorigenesis ... See more keywords
Vinculin in cell–cell and cell–matrix adhesions
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2511-3
Abstract: Vinculin was identified as a component of focal adhesions and adherens junctions nearly 40 years ago. Since that time, remarkable progress has been made in understanding its activation, regulation and function. Here we discuss the… read more here.
Keywords: cell matrix; cell; matrix adhesions; vinculin cell ... See more keywords
Evaluation of alginate modification effect on cell-matrix interaction, mechanotransduction and chondrogenesis of encapsulated MSCs
Sign Up to like & getrecommendations! Published in 2020 at "Cell and Tissue Research"
DOI: 10.1007/s00441-020-03216-7
Abstract: Mesenchymal stem cells (MSCs) are promising cell candidates for cartilage regeneration. Furthermore, it is important to control the cell-matrix interactions that have a direct influence on cell functions. Providing an appropriate microenvironment for cell differentiation… read more here.
Keywords: collagen; cell matrix; matrix; effect ... See more keywords
A hybrid model of intercellular tension and cell–matrix mechanical interactions in a multicellular geometry
Sign Up to like & getrecommendations! Published in 2020 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-020-01321-8
Abstract: Epithelial cells form continuous sheets of cells that exist in tensional homeostasis. Homeostasis is maintained through cell-to-cell junctions that distribute tension and balance forces between cells and their underlying matrix. Disruption of tensional homeostasis can… read more here.
Keywords: cell matrix; cell; model; geometry ... See more keywords
Cell-matrix reciprocity in 3D culture models with nonlinear elasticity
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2021.08.002
Abstract: Abstract Three-dimensional (3D) matrix models using hydrogels are powerful tools to understand and predict cell behavior. The interactions between the cell and its matrix, however is highly complex: the matrix has a profound effect on… read more here.
Keywords: cell matrix; culture; matrix; matrix reciprocity ... See more keywords
Tug of War at the Cell-Matrix Interface.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.03.032
Abstract: Mechanical interactions between a cell and its environment, or between cells, influence key developmental and physiologic processes as well as many aspect of disease (1,2). Indeed the ability of a cell to sense, produce, and… read more here.
Keywords: cell matrix; war cell; tug war; matrix interface ... See more keywords
Measurement of Cell-Matrix Adhesion at Single-Cell Resolution for Revealing the Functions of Biomaterials for Adherent Cell Culture.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b02653
Abstract: Cell adhesion is essential for a cell to maintain its functions, and biomaterials acting as the extracellular matrix (ECM) play a vital role. However, conventional methods for evaluating the functions of biomaterials become insufficient and… read more here.
Keywords: single cell; cell matrix; functions biomaterials; matrix adhesion ... See more keywords
Conjugated Polymer-Functionalized Stretchable Supramolecular Hydrogels to Monitor and Control Cellular Behavior.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c00460
Abstract: Natural extracellular matrix is formed by the assembly of small molecules and macromolecules into a hydrogel-like network that can mechanically support cells and involve in cellular processes. Here, we developed a fluorescent supramolecular hydrogel based… read more here.
Keywords: cell; behavior; hydrogel; supramolecular hydrogel ... See more keywords
Cell-matrix adhesion and cell-cell adhesion differentially control basal myosin oscillation and Drosophila egg chamber elongation
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms14708
Abstract: Pulsatile actomyosin contractility, important in tissue morphogenesis, has been studied mainly in apical but less in basal domains. Basal myosin oscillation underlying egg chamber elongation is regulated by both cell–matrix and cell–cell adhesions. However, the… read more here.
Keywords: cell matrix; cell cell; myosin oscillation; adhesion ... See more keywords
Recent advances in label-free imaging of cell-matrix adhesions.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d2cc06499e
Abstract: Cell-matrix adhesions play an essential role in mediating and regulating many biological processes. The adhesion receptors, typically transmembrane integrins, provide dynamic correlations between intracellular environments and extracellular matrixes (ECMs) by bi-directional signaling. In-depth investigations of… read more here.
Keywords: label free; cell; microscopy; cell matrix ... See more keywords
Integrin-linked kinase tunes cell–cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ1
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e20-02-0092
Abstract: Epithelial-mesenchymal transition (EMT) is a morphogenetic process that endows epithelial cells with migratory and invasive potential. Mechanical and chemical signals from the tumor microenvironment can activate the EMT program, thereby permitting cancer cells to invade… read more here.
Keywords: tgf; cell cell; emt; apoptosis ... See more keywords