Simultaneous Quantification of the Interplay Between Molecular Turnover and Cell Mechanics by AFM-FRAP.
Sign Up to like & getrecommendations! Published in 2019 at "Small"
DOI: 10.1002/smll.201902202
Abstract: Quantifying the adaptive mechanical behavior of living cells is essential for the understanding of their inner working and function. Yet, despite the establishment of quantitative methodologies correlating independent measurements of cell mechanics and its underlying… read more here.
Keywords: cell mechanics; microscopy; turnover; simultaneous quantification ... See more keywords
Reciprocity of Cell Mechanics with Extracellular Stimuli: Emerging Opportunities for Translational Medicine.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202107305
Abstract: Human cells encounter dynamic mechanical cues in healthy and diseased tissues, which regulate their molecular and biophysical phenotype, including intracellular mechanics as well as force generation. Recent developments in bio/nanomaterials and microfluidics permit exquisitely sensitive… read more here.
Keywords: mechanics; medicine; cell mechanics; translational medicine ... See more keywords
NanoIndentation, an ImageJ Plugin for the Quantification of Cell Mechanics.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1816-5_6
Abstract: Growth and morphogenesis in plants depend on cell wall mechanics and on turgor pressure. Nanoindentation methods, such as atomic force microscopy (AFM), enable measurements of mechanical properties of a tissue at subcellular resolution, while confocal… read more here.
Keywords: cell mechanics; microscopy; plugin; nanoindentation ... See more keywords
Bacterial Cell Mechanics Beyond Peptidoglycan.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in microbiology"
DOI: 10.1016/j.tim.2020.04.013
Abstract: The bacterial cell envelope plays essential roles in controlling cell shape, division, pathogenicity, and resistance against external stresses. In Escherichia coli, peptidoglycan (PG) has long been thought to be the primary component that conveys mechanical… read more here.
Keywords: cell mechanics; bacterial cell; cell; mechanics beyond ... See more keywords
Bacterial Cell Mechanics.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry"
DOI: 10.1021/acs.biochem.7b00346
Abstract: Cellular mechanical properties play an integral role in bacterial survival and adaptation. Historically, the bacterial cell wall and, in particular, the layer of polymeric material called the peptidoglycan were the elements to which cell mechanics… read more here.
Keywords: bacterial cell; biology; mechanics; cell mechanics ... See more keywords
Collective cell mechanics of epithelial shells with organoid-like morphologies
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-17535-4
Abstract: The study of organoids, artificially grown cell aggregates with the functionality and small-scale anatomy of real organs, is one of the most active areas of research in biology and biophysics, yet the basic physical origins… read more here.
Keywords: cell mechanics; anatomy; collective cell; cell ... See more keywords
Correlation of cell mechanics with the resistance to malignant transformation in naked mole rat fibroblasts.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr01633h
Abstract: Naked mole rats (NMRs) demonstrate exceptional longevity and resistance to cancer. Using a biochemical approach, it was previously shown that the treatment of mouse fibroblast cells with RasV12 oncogene and SV40 Large T antigen (viral… read more here.
Keywords: cell mechanics; malignant transformation; mechanics; treatment ... See more keywords
The transmembrane protein fibrocystin/polyductin regulates cell mechanics and cell motility.
Sign Up to like & getrecommendations! Published in 2019 at "Physical biology"
DOI: 10.1088/1478-3975/ab39fa
Abstract: Polycystic kidney disease is a disorder that leads to fluid filled cysts that replace normal renal tubes. During the process of cellular development and in the progression of the diseases, fibrocystin can lead to impaired… read more here.
Keywords: cell mechanics; cell migration; fibrocystin knockdown; cell ... See more keywords
Dissipation of contractile forces: the missing piece in cell mechanics
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e16-09-0672
Abstract: Mechanical forces are key regulators of cell and tissue physiology. The basic molecular mechanism of fiber contraction by the sliding of actin filament upon myosin leading to conformational change has been known for decades. The… read more here.
Keywords: dissipation contractile; cell; mechanics; cell mechanics ... See more keywords
Integrating blood cell mechanics, platelet adhesive dynamics and coagulation cascade for modelling thrombus formation in normal and diabetic blood
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2020.0834
Abstract: Normal haemostasis is an important physiological mechanism that prevents excessive bleeding during trauma, whereas the pathological thrombosis especially in diabetics leads to increased incidence of heart attacks and strokes as well as peripheral vascular events.… read more here.
Keywords: coagulation; diabetic blood; cell mechanics; blood ... See more keywords
Epithelial RAC1-dependent cytoskeleton dynamics controls cell mechanics, cell shedding and barrier integrity in intestinal inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Gut"
DOI: 10.1136/gutjnl-2021-325520
Abstract: Objective Increased apoptotic shedding has been linked to intestinal barrier dysfunction and development of inflammatory bowel diseases (IBD). In contrast, physiological cell shedding allows the renewal of the epithelial monolayer without compromising the barrier function.… read more here.
Keywords: cell; cell mechanics; rac1; barrier ... See more keywords