Emerging roles of β-cell mitochondria in type-2-diabetes.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular aspects of medicine"
DOI: 10.1016/j.mam.2019.100843
Abstract: Type-2-Diabetes (T2D) is the most common metabolic disease in the world today. It erupts as a result of peripheral insulin resistance combined with hyperinsulinemia followed by suppression of insulin secretion from pancreatic β-cells. Mitochondria play… read more here.
Keywords: insulin; cell mitochondria; emerging roles; type diabetes ... See more keywords
Cancer Cell Mitochondria Targeting by Pancratistatin Analogs is Dependent on Functional Complex II and III
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42957
Abstract: Enhanced mitochondrial stability and decreased dependence on oxidative phosphorylation confer an acquired resistance to apoptosis in cancer cells, but may present opportunities for therapeutic intervention. The compound pancratistatin (PST) has been shown to selectively induce… read more here.
Keywords: complex iii; cell mitochondria; cancer cells; cancer cell ... See more keywords
Corrigendum: Cancer Cell Mitochondria Targeting by Pancratistatin Analogs is Dependent on Functional Complex II and III
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/srep46998
Abstract: This corrects the article DOI: 10.1038/srep42957. read more here.
Keywords: targeting pancratistatin; cell mitochondria; corrigendum cancer; pancratistatin analogs ... See more keywords
Targeting cancer cell mitochondria as a therapeutic approach: recent updates.
Sign Up to like & getrecommendations! Published in 2017 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2017-0011
Abstract: Mitochondria play a key role in ATP generation, redox homeostasis and regulation of apoptosis. Due to the essential role of mitochondria in metabolism and cell survival, targeting mitochondria in cancer cells is considered as an… read more here.
Keywords: cell mitochondria; targeting cancer; targeting mitochondria; cancer cell ... See more keywords