SIK2 promotes ovarian cancer cell motility and metastasis by phosphorylating MYLK
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13208
Abstract: Salt‐inducible kinase 2 (SIK2; also known as serine/threonine‐protein kinase SIK2) is overexpressed in several cancers and has been implicated in cancer progression. However, the mechanisms by which SIK2 regulates cancer cell motility, migration and metastasis… read more here.
Keywords: ovarian cancer; cancer; cancer cell; cell motility ... See more keywords
High glucose promotes podocyte movement: From the perspective of single cell motility assay
Sign Up to like & getrecommendations! Published in 2023 at "Cell Biology International"
DOI: 10.1002/cbin.11996
Abstract: Podocytes are highly specialized glomerular epithelial cells that play a crucial role in maintaining the glomerular filtration barrier, impairment of which usually leads to proteinuria. The phenotypic alterations of podocytes are described to be one… read more here.
Keywords: cell; high glucose; single cell; motility assay ... See more keywords
Keeping the focus on biophysics and actin filaments in Nagoya: A report of the 2016 “now in actin” symposium
Sign Up to like & getrecommendations! Published in 2017 at "Cytoskeleton"
DOI: 10.1002/cm.21384
Abstract: Regulatory systems in living cells are highly organized, enabling cells to response to various changes in their environments. Actin polymerization and depolymerization are crucial to establish cytoskeletal networks to maintain muscle contraction, cell motility, cell… read more here.
Keywords: symposium; focus biophysics; cell motility; keeping focus ... See more keywords
Artificial Cytoskeleton Assembly for Synthetic Cell Motility.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200437
Abstract: Imitation of cellular processes in cell-like compartments is a current research focus in synthetic biology. Here, we introduce a method for assembling an artificial cytoskeleton in a synthetic cell model system based on a poly(N-isopropylacrylamide)… read more here.
Keywords: synthetic cell; artificial cytoskeleton; cytoskeleton; biology ... See more keywords
An Introduction to LFA-1/ICAM-1 Interactions in T-Cell Motility.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9036-8_1
Abstract: The inherent ability of T-cells to migrate is critical for a fully functional immune system, both in normal immune surveillance and for mounting an adaptive immune response. At the same time, inappropriate trafficking of T-cells… read more here.
Keywords: cell motility; icam interactions; introduction lfa; lfa icam ... See more keywords
Role of exopolysaccharide in salt stress resistance and cell motility of Mesorhizobium alhagi CCNWXJ12–2T
Sign Up to like & getrecommendations! Published in 2017 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-017-8114-y
Abstract: Mesorhizobium alhagi, a legume-symbiont soil bacterium that forms nodules with the desert plant Alhagi sparsifolia, can produce large amounts of exopolysaccharide (EPS) using mannitol as carbon source. However, the role of EPS in M. alhagi… read more here.
Keywords: alhagi ccnwxj12; resistance; role; cell motility ... See more keywords
Inflammatory breast cancer cells are characterized by abrogated TGFβ1-dependent cell motility and SMAD3 activity
Sign Up to like & getrecommendations! Published in 2020 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-020-05571-z
Abstract: Purpose Inflammatory breast cancer (IBC) is an aggressive form of breast cancer with elevated metastatic potential, characterized by tumor emboli in dermal and parenchymal lymph vessels. This study has investigated the hypothesis that TGFβ signaling… read more here.
Keywords: cell motility; ibc; expression; breast cancer ... See more keywords
PRR11 induces filopodia formation and promotes cell motility via recruiting ARP2/3 complex in non-small cell lung cancer cells
Sign Up to like & getrecommendations! Published in 2021 at "Genes and Diseases"
DOI: 10.1016/j.gendis.2021.02.012
Abstract: Abstract Filopodia, a finger-like structure and actin-rich plasma-membrane protrusion at the leading edge of the cell, has important roles in cell motility. However, the mechanisms of filopodia generation are not well-understood via the actin-related protein… read more here.
Keywords: arp2 complex; cell; filopodia formation; cell motility ... See more keywords
MTSS1 is epigenetically regulated in glioma cells and inhibits glioma cell motility
Sign Up to like & getrecommendations! Published in 2017 at "Translational Oncology"
DOI: 10.1016/j.tranon.2016.11.006
Abstract: Epigenetic silencing by DNA methylation in brain tumors has been reported for many genes, however, their function on pathogenesis needs to be evaluated. We investigated the MTSS1 gene, identified as hypermethylated by differential methylation hybridization… read more here.
Keywords: glioma; cell motility; hypermethylation; mtss1 ... See more keywords
Marine Depsipeptide Nobilamide I Inhibits Cancer Cell Motility and Tumorigenicity via Suppressing Epithelial–Mesenchymal Transition and MMP2/9 Expression
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c04520
Abstract: A cyclic depsipeptide, nobilamide I (1), along with the known peptide A-3302-B/TL-119 (2), was isolated from the saline cultivation of the marine-derived bacterium Saccharomonospora sp., strain CNQ-490. The planar structure of 1 was elucidated by… read more here.
Keywords: cell; mesenchymal transition; epithelial mesenchymal; depsipeptide nobilamide ... See more keywords
The lichen secondary metabolite atranorin suppresses lung cancer cell motility and tumorigenesis
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-08225-1
Abstract: Lichens are symbiotic organisms that produce various secondary metabolites. Here, different lichen extracts were examined to identify secondary metabolites with anti-migratory activity against human lung cancer cells. Everniastrum vexans had the most potent inhibitory activity,… read more here.
Keywords: atranorin; activity; cell motility; lung cancer ... See more keywords