Single-Cell mRNA-Seq Using the Fluidigm C1 System and Integrated Fluidics Circuits.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7834-2_10
Abstract: Single-cell mRNA-seq is a valuable tool to dissect expression profiles and to understand the regulatory network of genes. Microfluidics is well suited for single-cell analysis owing both to the small volume of the reaction chambers… read more here.
Keywords: single cell; cell; mrna seq; cell mrna ... See more keywords
Single Cell mRNA Cytometry via Sequence-Specific Nanoparticle Clustering and Trapping
Sign Up to like & getrecommendations! Published in 2018 at "Nature chemistry"
DOI: 10.1038/s41557-018-0025-8
Abstract: Cell-to-cell variation in gene expression creates a need for techniques that can characterize expression at the level of individual cells. This is particularly true for rare circulating tumour cells, in which subtyping and drug resistance… read more here.
Keywords: single cell; mrna cytometry; level; expression ... See more keywords
Single-Cell mRNA Sequencing in Cancer Research: Integrating the Genomic Fingerprint
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2017.00073
Abstract: Critical cancer mutations are often regional and mosaic, confounding the efficacy of targeted therapeutics. Single cell mRNA sequencing (scRNA-seq) has enabled unprecedented studies of intra-tumor heterogeneity and its role in cancer progression, metastasis, and treatment… read more here.
Keywords: single cell; scrna seq; mrna sequencing; cancer ... See more keywords