A universal framework for single-cell multi-omics data integration with graph convolutional networks
Sign Up to like & getrecommendations! Published in 2023 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbad081
Abstract: Abstract Single-cell omics data are growing at an unprecedented rate, whereas effective integration of them remains challenging due to different sequencing methods, quality, and expression pattern of each omics data. In this study, we propose… read more here.
Keywords: cell; universal framework; integration; single cell ... See more keywords
PyLiger: scalable single-cell multi-omic data integration in Python.
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac190
Abstract: MOTIVATION LIGER (Linked Inference of Genomic Experimental Relationships) is a widely used R package for single-cell multi-omic data integration. However, many users prefer to analyze their single-cell datasets in Python, which offers an attractive syntax… read more here.
Keywords: cell; multi omic; data integration; single cell ... See more keywords
Clustering single-cell multi-omics data with MoClust
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac736
Abstract: Abstract Motivation Single-cell multi-omics sequencing techniques have rapidly developed in the past few years. Clustering analysis with single-cell multi-omics data may give us novel perspectives to dissect cellular heterogeneity. However, multi-omics data have the properties… read more here.
Keywords: cell multi; multi omics; single cell; omics data ... See more keywords
Single-cell multi-omics of human preimplantation embryos shows susceptibility to glucocorticoids
Sign Up to like & getrecommendations! Published in 2022 at "Genome Research"
DOI: 10.1101/gr.276665.122
Abstract: The preconceptual, intrauterine, and early life environments can have a profound and long-lasting impact on the developmental trajectories and health outcomes of the offspring. Given the relatively low success rates of assisted reproductive technologies (ART;… read more here.
Keywords: cell; multi omics; single cell; omics human ... See more keywords
Multi-Cell Multi-User Massive FD-MIMO: Downlink Precoding and Throughput Analysis
Sign Up to like & getrecommendations! Published in 2019 at "IEEE Transactions on Wireless Communications"
DOI: 10.1109/twc.2018.2882386
Abstract: In this paper, downlink (DL) precoding and power allocation strategies are identified for a time-division-duplex multi-cell multi-user massive full-dimension MIMO network. Utilizing channel reciprocity, DL channel state information feedback is eliminated and the DL multi-user… read more here.
Keywords: mimo; multi cell; cell multi; downlink precoding ... See more keywords
scONE-seq: A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.abp8901
Abstract: Single-cell multi-omics can provide a unique perspective on tumor cellular heterogeneity. Most previous single-cell whole-genome RNA sequencing (scWGS-RNA-seq) methods demonstrate utility with intact cells from fresh samples. Among them, many are not applicable to frozen… read more here.
Keywords: cell; multi omics; single cell; scone seq ... See more keywords
Abstract IA008: Charting normal and malignant differentiation topologies with single-cell multi-omics
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Research"
DOI: 10.1158/1538-7445.evodyn22-ia008
Abstract: Somatic evolution is a novel emerging frontier in human biology, as cells within diverse normal and malignant tissues have been shown to diversify and undergo selection. We and others have shown that somatic evolution is… read more here.
Keywords: cell; nature; single cell; cell multi ... See more keywords
Characterizing Chemoautotrophy and Heterotrophy in Marine Archaea and Bacteria With Single-Cell Multi-isotope NanoSIP
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.02682
Abstract: Characterizing and quantifying in situ metabolisms remains both a central goal and challenge for environmental microbiology. Here, we used a single-cell, multi-isotope approach to investigate the anabolic activity of marine microorganisms, with an emphasis on… read more here.
Keywords: single cell; marine; cell multi; multi isotope ... See more keywords