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   Articles with "cell multi" as a keyword



Expanding the Dimensions of Single-Cell Multi-Omics To Include Mitochondrial DNA through Fixation and Permeabilization.

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recommendations! Published in 2025 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.4c06777

Abstract: Single-cell multi-omics has transformed our understanding of cellular heterogeneity, yet incorporating mitochondrial DNA (mtDNA) remains challenging. Recent studies underscore the critical role of fixation and permeabilization techniques in preserving sample integrity, optimizing Tn5 tagmentation, and… read more here.

Keywords: multi omics; single cell; fixation permeabilization; cell ... See more keywords

A universal framework for single-cell multi-omics data integration with graph convolutional networks

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recommendations! Published in 2023 at "Briefings in Bioinformatics"

DOI: 10.1093/bib/bbad081

Abstract: Abstract Single-cell omics data are growing at an unprecedented rate, whereas effective integration of them remains challenging due to different sequencing methods, quality, and expression pattern of each omics data. In this study, we propose… read more here.

Keywords: cell; universal framework; integration; single cell ... See more keywords

scMNMF: a novel method for single-cell multi-omics clustering based on matrix factorization

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recommendations! Published in 2024 at "Briefings in Bioinformatics"

DOI: 10.1093/bib/bbae228

Abstract: Abstract Motivation The technology for analyzing single-cell multi-omics data has advanced rapidly and has provided comprehensive and accurate cellular information by exploring cell heterogeneity in genomics, transcriptomics, epigenomics, metabolomics and proteomics data. However, because of… read more here.

Keywords: multi omics; single cell; matrix factorization; cell ... See more keywords

FactVAE: a factorized variational autoencoder for single-cell multi-omics data integration analysis

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recommendations! Published in 2025 at "Briefings in Bioinformatics"

DOI: 10.1093/bib/bbaf157

Abstract: Abstract Single-cell multi-omics technologies have revolutionized the study of cell states and functions by simultaneously profiling multiple molecular layers within individual cells. However, existing methods for integrating these data struggle to preserve critical feature information… read more here.

Keywords: variational autoencoder; multi omics; single cell; cell ... See more keywords

PyLiger: scalable single-cell multi-omic data integration in Python.

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recommendations! Published in 2022 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btac190

Abstract: MOTIVATION LIGER (Linked Inference of Genomic Experimental Relationships) is a widely used R package for single-cell multi-omic data integration. However, many users prefer to analyze their single-cell datasets in Python, which offers an attractive syntax… read more here.

Keywords: cell; multi omic; data integration; single cell ... See more keywords

Clustering single-cell multi-omics data with MoClust

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recommendations! Published in 2022 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btac736

Abstract: Abstract Motivation Single-cell multi-omics sequencing techniques have rapidly developed in the past few years. Clustering analysis with single-cell multi-omics data may give us novel perspectives to dissect cellular heterogeneity. However, multi-omics data have the properties… read more here.

Keywords: cell multi; multi omics; single cell; omics data ... See more keywords

Single-cell multi-omics of human preimplantation embryos shows susceptibility to glucocorticoids

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recommendations! Published in 2022 at "Genome Research"

DOI: 10.1101/gr.276665.122

Abstract: The preconceptual, intrauterine, and early life environments can have a profound and long-lasting impact on the developmental trajectories and health outcomes of the offspring. Given the relatively low success rates of assisted reproductive technologies (ART;… read more here.

Keywords: cell; multi omics; single cell; omics human ... See more keywords

Multi-Cell Multi-User Massive FD-MIMO: Downlink Precoding and Throughput Analysis

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recommendations! Published in 2019 at "IEEE Transactions on Wireless Communications"

DOI: 10.1109/twc.2018.2882386

Abstract: In this paper, downlink (DL) precoding and power allocation strategies are identified for a time-division-duplex multi-cell multi-user massive full-dimension MIMO network. Utilizing channel reciprocity, DL channel state information feedback is eliminated and the DL multi-user… read more here.

Keywords: mimo; multi cell; cell multi; downlink precoding ... See more keywords

Dynamic Aerial Reconfigurable Intelligent Surface Aided Multi-Cell Multi-User Communications

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recommendations! Published in 2024 at "IEEE Transactions on Wireless Communications"

DOI: 10.1109/twc.2024.3441093

Abstract: In aerial reconfigurable intelligent surface (RIS) aided networks, high line-of-sight (LoS) and agility characteristics provide favorable conditions for RIS reflection. However, this also introduces extra LoS RIS reflection interference, especially when aerial RIS is fixedly… read more here.

Keywords: multi cell; aided multi; reconfigurable intelligent; cell multi ... See more keywords

scONE-seq: A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors

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recommendations! Published in 2023 at "Science Advances"

DOI: 10.1126/sciadv.abp8901

Abstract: Single-cell multi-omics can provide a unique perspective on tumor cellular heterogeneity. Most previous single-cell whole-genome RNA sequencing (scWGS-RNA-seq) methods demonstrate utility with intact cells from fresh samples. Among them, many are not applicable to frozen… read more here.

Keywords: cell; multi omics; single cell; scone seq ... See more keywords

Abstract IA008: Charting normal and malignant differentiation topologies with single-cell multi-omics

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recommendations! Published in 2022 at "Cancer Research"

DOI: 10.1158/1538-7445.evodyn22-ia008

Abstract: Somatic evolution is a novel emerging frontier in human biology, as cells within diverse normal and malignant tissues have been shown to diversify and undergo selection. We and others have shown that somatic evolution is… read more here.

Keywords: cell; nature; single cell; cell multi ... See more keywords