Articles with "cell niche" as a keyword



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Quantum Sensing in a Physiological-Like Cell Niche Using Fluorescent Nanodiamonds Embedded in Electrospun Polymer Nanofibers.

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Published in 2019 at "Small"

DOI: 10.1002/smll.201900455

Abstract: Fluorescent nanodiamonds (fNDs) containing nitrogen vacancy (NV) centers are promising candidates for quantum sensing in biological environments. This work describes the fabrication and implementation of electrospun poly lactic-co-glycolic acid (PLGA) nanofibers embedded with fNDs for… read more here.

Keywords: microscopy; fluorescent nanodiamonds; quantum sensing; cell niche ... See more keywords
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Molecular control of the female germline stem cell niche size in Drosophila

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Published in 2019 at "Cellular and Molecular Life Sciences"

DOI: 10.1007/s00018-019-03223-0

Abstract: Adult stem cells have a unique capacity to renew themselves and generate differentiated cells that are needed in the body. These cells are recruited and maintained by the surrounding microenvironment, known as the stem cell… read more here.

Keywords: cell niche; germline stem; stem cell; niche ... See more keywords
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Home sweet home: the neural stem cell niche throughout development and after injury

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Published in 2017 at "Cell and Tissue Research"

DOI: 10.1007/s00441-017-2658-0

Abstract: Neural stem cells and their progeny reside in two distinct neurogenic niches within the mammalian brain: the subventricular zone and the dentate gyrus. The interplay between the neural stem cells and the niche in which… read more here.

Keywords: home; cell niche; cell; stem ... See more keywords
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Regenerative medicine for male infertility: a focus on stem cell niche injury models.

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Published in 2022 at "Biomedical journal"

DOI: 10.1016/j.bj.2022.01.015

Abstract: Stem and progenitor cells located within stem cell niches maintain the renewal and regeneration of tissues and organs throughout the life of an adult organism. Stem cell niche component dysfunction might alter the activity of… read more here.

Keywords: stem cell; medicine; cell niche; stem ... See more keywords
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Mathematical modelling of the hematopoietic stem cell-niche system: Clonal dominance based on stem cell fitness.

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Published in 2021 at "Journal of theoretical biology"

DOI: 10.1016/j.jtbi.2021.110620

Abstract: Human blood cell production is maintained by hematopoietic stem cells (HSC) which give rise to all types of mature blood cells. Experimental observation of HSC in their physiologic bone-marrow microenvironment, the so-called stem cell niche,… read more here.

Keywords: hsc; stem cell; model; cell niche ... See more keywords
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A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate

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Published in 2019 at "Nature"

DOI: 10.1038/s41586-019-0989-6

Abstract: Longitudinal bone growth in children is sustained by growth plates, narrow discs of cartilage that provide a continuous supply of chondrocytes for endochondral ossification1. However, it remains unknown how this supply is maintained throughout childhood… read more here.

Keywords: cell; epiphyseal growth; stem cell; cell niche ... See more keywords
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Wnt ligand presentation and reception: from the stem cell niche to tissue engineering

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Published in 2017 at "Open Biology"

DOI: 10.1098/rsob.170140

Abstract: Stem cells reside in niches where spatially restricted signals maintain a delicate balance between stem cell self-renewal and differentiation. Wnt family proteins are particularly suited for this role as they are modified by lipids, which… read more here.

Keywords: stem; stem cells; cell niche; stem cell ... See more keywords
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Higher-order epistasis shapes natural variation in germ stem cell niche activity

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Published in 2022 at "Nature Communications"

DOI: 10.1101/2022.11.04.515229

Abstract: Summary Natural quantitative variation in developmental processes must be driven by allelic variation. Yet, the genotype-phenotype relationships underlying developmental system variation are understudied due to their inherent complexity. Taking advantage of the simple Caenorhabditis elegans… read more here.

Keywords: germ stem; cell niche; stem cell; variation ... See more keywords
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Intestinal Stem Cell Niche: The Extracellular Matrix and Cellular Components

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Published in 2017 at "Stem Cells International"

DOI: 10.1155/2017/7970385

Abstract: The intestinal epithelium comprises a monolayer of polarised columnar cells organised along the crypt-villus axis. Intestinal stem cells reside at the base of crypts and are constantly nourished by their surrounding niche for maintenance, self-renewal,… read more here.

Keywords: stem; cell niche; stem cell; intestinal stem ... See more keywords
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Intestinal Stem Cell Niche Insights Gathered from Both In Vivo and Novel In Vitro Models

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Published in 2017 at "Stem Cells International"

DOI: 10.1155/2017/8387297

Abstract: Intestinal stem cells are located at the base of the crypts and are surrounded by a complex structure called niche. This environment is composed mainly of epithelial cells and stroma which provides signals that govern… read more here.

Keywords: cell niche; intestinal stem; stem cell; stem ... See more keywords
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Hacking the stem cell niche.

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Published in 2017 at "Blood"

DOI: 10.1182/blood-2017-04-777789

Abstract: In this issue of Blood , Stoddart et al think outside of the stem cell “box” to identify a therapeutically tractable pathway in del(5q) myelodysplastic syndrome (MDS), through blocking pathologically activated Wnt signaling arising within… read more here.

Keywords: stem cell; cell niche; stem; hacking stem ... See more keywords