Multiscale Monte Carlo simulations of gold nanoparticle dose-enhanced radiotherapy II. Cellular dose enhancement within macroscopic tumor models.
Sign Up to like & getrecommendations! Published in 2023 at "Medical physics"
DOI: 10.1002/mp.16460
Abstract: BACKGROUND Gold NanoParticle (GNP) dose-enhanced radiation therapy (GNPT) requires consideration of physics across macro- to microscopic length scales, however, this presents computational challenges that have limited previous investigations. PURPOSE To develop and apply multiscale Monte Carlo… read more here.
Keywords: dose; gold; gold concentrations; tumor ... See more keywords
Ex situ and in situ surface-enhanced Raman spectroscopy for macromolecular profiles of cell nucleus
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-01981-1
Abstract: AbstractCytobiological methods for cell nucleus–related studies start with the extraction processes of intranuclear components with many cell lysis buffers, following with the structural characterizations and quantitative analysis of the extracted components. In this study, we… read more here.
Keywords: situ surface; surface enhanced; cell nucleus; enhanced raman ... See more keywords
Disassembly of the lens fiber cell nucleus to create a clear lens: The p27 descent.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental eye research"
DOI: 10.1016/j.exer.2016.02.011
Abstract: The eye lens is unique among tissues: it is transparent, does not form tumors, and the majority of its cells degrade their organelles, including their cell nuclei. A mystery for over a century, there has… read more here.
Keywords: cell nucleus; fiber cell; lens fiber; nucleus create ... See more keywords
Reproductive Toxicity Evaluation of Graphene-Based Tumor Cell Nucleus-Targeting Fluorescent Nanoprobes on Reproduction and Offspring Health.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00934
Abstract: A new graphene-based fluorescent nanoprobe for tumor cell nucleus (GTTNs) was synthesized in our laboratory that penetrates the cell membrane and particularly targets cancer cell nucleus and displays tremendous potential for clinical applications. Although acute… read more here.
Keywords: toxicity; tumor cell; mice; cell nucleus ... See more keywords
Variation in genome size, cell and nucleus volume, chromosome number and rDNA loci among duckweeds
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-39332-w
Abstract: Duckweeds are small, free-floating, largely asexual and highly neotenous organisms. They display the most rapid growth among flowering plants and are of growing interest in aquaculture and genome biology. Genomic and chromosomal data are still… read more here.
Keywords: cell nucleus; size; rdna loci; genome size ... See more keywords
The cell nucleus. A study in Burgundy
Sign Up to like & getrecommendations! Published in 2019 at "Nucleus"
DOI: 10.1080/19491034.2019.1649835
Abstract: ABSTRACT Wilhelm Bernhard’s revolutionary microscopy techniques helped him put forward the hypothesis of specialized compartmentalization of the nucleus. He also described for the first time the nuclear bodies and peri-chromatin fibrils, and demonstrated that these… read more here.
Keywords: cell; cell nucleus; microscopy; nucleus study ... See more keywords
The Nuclear Option: Evidence Implicating the Cell Nucleus in Mechanotransduction.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biomechanical engineering"
DOI: 10.1115/1.4035350
Abstract: Biophysical stimuli presented to cells via microenvironmental properties (e.g., alignment and stiffness) or external forces have a significant impact on cell function and behavior. Recently, the cell nucleus has been identified as a mechanosensitive organelle… read more here.
Keywords: cell nucleus; nuclear mechanotransduction; evidence; nucleus mechanotransduction ... See more keywords
PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Virology"
DOI: 10.1128/jvi.00825-18
Abstract: DNA viruses, including hepatitis B virus and herpes simplex virus, induce a series of immune responses in the host and lead to human public health concerns worldwide. In addition to cytokines in the cytoplasm, restriction… read more here.
Keywords: restriction; cell nucleus; dna; viral episomal ... See more keywords
Angiotensin-II impairs the cellular antioxidant defense capacity in the hypothalamic cardio regulatory nucleus of spontaneously hypertensive rats contributing to hypertension
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5734703
Abstract: Oxidative stress is a central mechanism underlying Angiotensin II (AngII)-induced enhanced sympathetic outflow within brain cardio-regulatory nuclei in neurogenic hypertension. Yet, a causal association between AngII, Nrf2 (nuclear factor erythroid 2-related factor 2 - the… read more here.
Keywords: nucleus cytosol; hypertension; expression; physiology ... See more keywords
Molecular conditions of the cell nucleus remodelling/reprogramming process and nuclear- transferred embryo development in the intraooplasmic karyoplast injection technique: a review
Sign Up to like & getrecommendations! Published in 2018 at "Czech Journal of Animal Science"
DOI: 10.17221/4142-cjas
Abstract: The introduction of cell nuclei into enucleated recipient cells, beyond enucleation, is the most sig- nificant stage of somatic cloning procedure. Microsurgical transfer of somatic nuclei can be an alternative method of clonal nuclear-cytoplasmic hybrid… read more here.
Keywords: technique; nucleus remodelling; conditions cell; cell nucleus ... See more keywords
Investigating Dynamic Molecular Events in Melanoma Cell Nucleus During Photodynamic Therapy by SERS
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2018.00665
Abstract: Photodynamic therapy (PDT) involves the uptake of photosensitizers by cancer cells and the irradiation of a light with a specific wavelength to trigger a series of photochemical reactions based on the generation of reactive oxygen,… read more here.
Keywords: melanoma cell; photodynamic therapy; cell nucleus; molecular events ... See more keywords