Ophiopogonin D attenuates the progression of murine systemic lupus erythematosus by reducing B cell numbers.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23361
Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by immune abnormalities leading to multi-organ damage. The activation of autoreactive B cell differentiation will lead to the production of pathogenic autoantibodies, contributing to the… read more here.
Keywords: cell; reducing cell; cell numbers; systemic lupus ... See more keywords
Increased testicular estradiol during the neonatal interval reduces Sertoli cell numbers.
Sign Up to like & getrecommendations! Published in 2018 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2018.01.002
Abstract: Previous studies have demonstrated that reducing endogenous testicular estradiol in neonatal boars would stimulate increased proliferation of Sertoli cells during the neonatal interval. The objective of this experiment was to determine if increasing testicular estradiol… read more here.
Keywords: neonatal interval; sertoli cell; cell numbers; testicular estradiol ... See more keywords
Increased Uterine NK cell numbers and perforin expression during the implantation phase in IVF Cycles with GnRH Antagonist Protocol
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep39912
Abstract: GnRH antagonist negatively affects endometrial receptivity in in vitro fertilization (IVF) cycles, however, its underlying mechanism remains unclear. To explore its target molecules, we studied endometria in the window phase of fixed GnRH antagonist, low-dose… read more here.
Keywords: gnrh antagonist; group; cell numbers; expression ... See more keywords
Impaired B-Cell Maturation Contributes to Reduced B Cell Numbers and Poor Prognosis in Sepsis.
Sign Up to like & getrecommendations! Published in 2019 at "Shock"
DOI: 10.1097/shk.0000000000001478
Abstract: BACKGROUND Reduced B cell numbers plays a critical role in sepsis immunosuppression. The role of B-cell maturation regulated by T follicular helper (Tfh) cells in reduced B cell numbers during sepsis remains unclear. We tested… read more here.
Keywords: reduced cell; sepsis; cell numbers; cell maturation ... See more keywords
Quantitative restoration of immune defense in old animals determined by naive antigen-specific CD8 T-cell numbers.
Sign Up to like & getrecommendations! Published in 2022 at "Aging cell"
DOI: 10.1111/acel.13582
Abstract: Older humans and animals often exhibit reduced immune responses to infection and vaccination, and this often directly correlates to the numbers and frequency of naive T (Tn) cells. We found such a correlation between reduced… read more here.
Keywords: cell numbers; cd8 cells; specific cd8; cd8 ... See more keywords
Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo
Sign Up to like & getrecommendations! Published in 2017 at "Wellcome Open Research"
DOI: 10.12688/wellcomeopenres.10308.1
Abstract: Background. The myeloid enzyme 12/15-lipoxygenase (LOX), which generates bioactive oxidized lipids, has been implicated in numerous inflammatory diseases, with several studies demonstrating an improvement in pathology in mice lacking the enzyme. However, the ability of… read more here.
Keywords: immune antibody; lox; innate immune; cell numbers ... See more keywords
Hypoxic pulmonary endothelial cells release epidermal growth factor leading to vascular smooth muscle cell arginase‐2 expression and proliferation
Sign Up to like & getrecommendations! Published in 2022 at "Physiological Reports"
DOI: 10.14814/phy2.15342
Abstract: The hallmark of pulmonary hypertension (PH) is vascular remodeling. We have previously shown that human pulmonary microvascular endothelial cells (hPMVEC) respond to hypoxia with epidermal growth factor (EGF) mediated activation of the receptor tyrosine kinase,… read more here.
Keywords: cell; viable cell; proliferation; hcm ... See more keywords
Interleukin-6 requires JAK to stimulate inner cell mass expansion in bovine embryos.
Sign Up to like & getrecommendations! Published in 2019 at "Reproduction"
DOI: 10.1530/rep-19-0286
Abstract: Supplementing interleukin-6 (IL6) to in vitro produced bovine embryos increases inner cell mass (ICM) cell numbers in blastocysts. A series of studies were completed to further dissect this effect. Treatment with IL6 increased ICM cell… read more here.
Keywords: cell mass; inner cell; icm cell; cell numbers ... See more keywords
Photoperiodic Effects on Diurnal Rhythms in Cell Numbers of Peripheral Leukocytes in Domestic Pigs
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.00393
Abstract: The photoperiod is known to modulate immune cell number and function and is regarded essential for seasonal disease susceptibility. In addition, diurnal variations in the immune system are regarded important for immune competence. Whereas few… read more here.
Keywords: photoperiodic effects; cell numbers; rhythms; diurnal rhythms ... See more keywords
Exogenous FGF-1 Differently Regulates Oligodendrocyte Replenishment in an SCI Repair Model and Cultured Cells
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10112724
Abstract: We studied the phenotypes in an oligodendrocyte genesis site at the acute stage of spinal cord injury, when we observed regenerated ascending neurites. Pan-oligodendrocyte marker OLIG2+ cells were more in fibroblast growth factor (FGF)-1-treated rats… read more here.
Keywords: group; cell numbers; model; spinal cord ... See more keywords