Single Cell Omics: From Assay Design to Biomedical Application
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology Journal"
DOI: 10.1002/biot.201900262
Abstract: Given the existence of cell heterogeneity, single cell analysis is undergoing a rapid expansion for life science and precision medicine. Recent numerous innovations in analytical platforms and instruments have re‐energized the field and led to… read more here.
Keywords: single cell; design biomedical; assay design; omics assay ... See more keywords
scGCN is a graph convolutional networks algorithm for knowledge transfer in single cell omics
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-24172-y
Abstract: Single-cell omics is the fastest-growing type of genomics data in the literature and public genomics repositories. Leveraging the growing repository of labeled datasets and transferring labels from existing datasets to newly generated datasets will empower… read more here.
Keywords: single cell; graph convolutional; knowledge transfer; cell ... See more keywords
Recent advances of osteoimmunology research in rheumatoid arthritis: From single-cell omics approach.
Sign Up to like & getrecommendations! Published in 2023 at "Chinese medical journal"
DOI: 10.1097/cm9.0000000000002678
Abstract: ABSTRACT Cellular immune responses as well as generalized and periarticular bone loss are the key pathogenic features of rheumatoid arthritis (RA). Under the pathological conditions of RA, dysregulated inflammation and immune processes tightly interact with… read more here.
Keywords: cell; cell omics; bone; rheumatoid arthritis ... See more keywords
Single-cell omics analysis reveals functional diversification of hepatocytes during liver regeneration
Sign Up to like & getrecommendations! Published in 2020 at "JCI Insight"
DOI: 10.1172/jci.insight.141024
Abstract: Adult liver has enormous regenerative capacity; it can regenerate after losing two-thirds of its mass while sustaining essential metabolic functions. How the liver balances dual demands for increased proliferative activity with maintenance of organ function… read more here.
Keywords: single cell; chromatin landscapes; liver regeneration; regeneration ... See more keywords
Single-cell omics: A new direction for functional genetic research in human diseases and animal models
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1100016
Abstract: Over the past decade, with the development of high-throughput single-cell sequencing technology, single-cell omics has been emerged as a powerful tool to understand the molecular basis of cellular mechanisms and refine our knowledge of diverse… read more here.
Keywords: cell; cell omics; animal models; human diseases ... See more keywords
Sparsely Connected Autoencoders: A Multi-Purpose Tool for Single Cell omics Analysis
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms222312755
Abstract: Background: Biological processes are based on complex networks of cells and molecules. Single cell multi-omics is a new tool aiming to provide new incites in the complex network of events controlling the functionality of the… read more here.
Keywords: tool; single cell; cell; sparsely connected ... See more keywords