Scleraxis: a force-responsive cell phenotype regulator
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Physiology"
DOI: 10.1016/j.cophys.2017.07.004
Abstract: Changes in cell phenotype underlie many of the body's responses to altered environmental conditions, stress, or damage, resulting in both physiological and pathophysiological alterations to tissue function. Transcriptional regulators play a critical role in reprogramming… read more here.
Keywords: force responsive; cell phenotype; scleraxis force; role ... See more keywords
FRI0001 Extended oligoarticular and polyarticular juvenile idiopathic arthritis patients have a similar b cell phenotype when compared to established rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.5963
Abstract: Background Our group has recently described that the majority of polyarticular juvenile idiopathic arthritis (pJIA) and a large fraction of extended oligoarticular JIA (oJIA) patients fulfil classification criteria for rheumatoid arthritis (RA) in adulthood. B… read more here.
Keywords: extended ojia; cell phenotype; jia patients; arthritis ... See more keywords
The GP.Mur red cell phenotype (higher band 3 expression) affects respiratory frequency and the inspiratory/expiratory ratio in a breath cycle during exhaustive exercise
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5732219
Abstract: The GP.Mur red cell phenotype is characterized by the unique presence of glycophorin B-A-B hybrid protein on the erythrocyte membrane which promotes band 3 expression. Band 3, or anion exchanger-1, transports HCO3 - across the… read more here.
Keywords: band; red cell; mur red; physiology ... See more keywords
Cell Phenotype Classification Based on Joint of Texture Information and Multilayer Feature Extraction in DenseNet
Sign Up to like & getrecommendations! Published in 2022 at "Computational Intelligence and Neuroscience"
DOI: 10.1155/2022/6895833
Abstract: Cell phenotype classification is a critical task in many medical applications, such as protein localization, gene effect identification, and cancer diagnosis in some types. Fluorescence imaging is the most efficient tool to analyze the biological… read more here.
Keywords: phenotype classification; feature; level; texture ... See more keywords
Transformed Mycosis Fungoides with a Cytotoxic T-Cell Phenotype
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Surgical Pathology"
DOI: 10.1177/10668969221084267
Abstract: Mycosis fungoides (MF) is a cutaneous T-cell lymphoma and occasionally undergo large cell transformation (transformed MF, TMF), resulting in a poorer clinical outcome. We describe a case of TMF with an immunophenotypic shift. MF showed… read more here.
Keywords: mycosis fungoides; cell; transformed mycosis; cell phenotype ... See more keywords
Characterization of MCF-12A cell phenotype, response to estrogens, and growth in 3D
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Cell International"
DOI: 10.1186/s12935-018-0534-y
Abstract: BackgroundThree-dimensional cultures of mammary epithelial cells allow for biologically-relevant studies of the development of the mammary gland in rodents and humans under normal and pathological conditions, like carcinogenesis. Under these conditions, mammotropic hormones play significant… read more here.
Keywords: 12a cell; cell phenotype; mcf 12a; 12a cells ... See more keywords
SFRP1 induces a stem cell phenotype in prostate cancer cells
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1096923
Abstract: Prostate cancer (PCa) ranks second in incidence and sixth in deaths globally. The treatment of patients with castration-resistant prostate cancer (CRPC) continues to be a significant clinical problem. Emerging evidence suggests that prostate cancer progression… read more here.
Keywords: cell; prostate cancer; stem cell; cell phenotype ... See more keywords
Changes in T Cell and Dendritic Cell Phenotype from Mid to Late Pregnancy Are Indicative of a Shift from Immune Tolerance to Immune Activation
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.01138
Abstract: During pregnancy, the mother allows the immunologically distinct fetoplacental unit to develop and grow. Opinions are divided as to whether this represents a state of fetal-specific tolerance or of a generalized suppression of the maternal… read more here.
Keywords: pregnancy; tolerance; cell phenotype; activation ... See more keywords
Cirrhosis Hampers Early and Rapid Normalization of Natural Killer Cell Phenotype and Function in Hepatitis C Patients Undergoing Interferon-Free Therapy
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00129
Abstract: Background: Chronic hepatitis C virus (HCV) infection impairs natural killer (NK) cell phenotype and function. Whether restoration of NK cells occurs after successful interferon (IFN)-free therapies remains a controversial issue. Aim: To analyze how HCV-related… read more here.
Keywords: therapy; cirrhosis; natural killer; cell phenotype ... See more keywords
Cancer Cell Phenotype Plasticity as a Driver of Immune Escape in Melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.873116
Abstract: Immunotherapies blocking negative immune checkpoints are now approved for the treatment of a growing number of cancers. However, even in metastatic melanoma, where sustained responses are observed, a significant number of patients still do not… read more here.
Keywords: plasticity; melanoma; cell phenotype; cell ... See more keywords
The Stem Cell Phenotype of Aggressive Breast Cancer Cells
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11030340
Abstract: Aggressive cancer cells are characterized by their capacity to proliferate indefinitely and to propagate a heterogeneous tumor comprised of subpopulations with varying degrees of metastatic propensity and drug resistance properties. Particularly daunting is the challenge… read more here.
Keywords: cancer; stem cell; cell phenotype; breast cancer ... See more keywords