Novel immune cell phenotypes in spondyloarthritis pathogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in Immunopathology"
DOI: 10.1007/s00281-021-00837-0
Abstract: Spondyloarthritis (SpA) is a heterogeneous group of chronic inflammatory diseases of unknown etiology. Over time, the plethora of cellular elements involved in its pathogenesis has progressively enriched together with the definition of specific cytokine pathways.… read more here.
Keywords: cell phenotypes; immune cell; novel immune; new cellular ... See more keywords
Droplet Tn-Seq combines microfluidics with Tn-Seq for identifying complex single-cell phenotypes
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13719-9
Abstract: While Tn-Seq is a powerful tool to determine genome-wide bacterial fitness in high-throughput, culturing transposon-mutant libraries in pools can mask community or other complex single-cell phenotypes. Droplet Tn-Seq (dTn-Seq) solves this problem by microfluidics facilitated… read more here.
Keywords: single cell; complex single; cell phenotypes; droplet seq ... See more keywords
Differential effects of biological DMARDs on peripheral immune cell phenotypes in patients with rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2018 at "Rheumatology"
DOI: 10.1093/rheumatology/kex012
Abstract: Objective The aim of this study was to assess the therapeutic effects of biological DMARDs (bDMARDs) on the diversity of immune cell phenotypes in peripheral blood of patients with RA. Methods Peripheral immune cell phenotypes… read more here.
Keywords: cell phenotypes; immune cell; effects biological; biological dmards ... See more keywords
Ratiometric control of cell phenotypes in monostrain microbial consortia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2022.0335
Abstract: We address the problem of regulating and keeping at a desired balance the relative numbers between cells exhibiting a different phenotype within a monostrain microbial consortium. We propose a strategy based on the use of… read more here.
Keywords: cell phenotypes; control; ratiometric control; control cell ... See more keywords
Predict disease progression from T‐cell phenotypes in northern pig‐tailed macaques (Macaca leonina) during SIVmac239 infection
Sign Up to like & getrecommendations! Published in 2017 at "Immunology"
DOI: 10.1111/imm.12794
Abstract: Macaca leonina (northern pig‐tailed macaques, NPMs) have variable disease progression during SIVmac239 infection. In the present study, we analysed, for the first time, the correlations between T‐cell phenotypes and disease progression in NPMs during SIVmac239… read more here.
Keywords: cell phenotypes; cell; sivmac239 infection; disease progression ... See more keywords
Systemic inflammation and immune cell phenotypes are associated with neuro‐psychiatric symptoms in patients with chronic inflammatory liver diseases
Sign Up to like & getrecommendations! Published in 2018 at "Liver International"
DOI: 10.1111/liv.13869
Abstract: Chronic inflammatory liver diseases are frequently associated with neuropsychiatric and cognitive dysfunctions. We hypothesized that symptomatic patients may show altered levels of soluble inflammatory mediators (SIMs) as well as changes in immune cell phenotypes. read more here.
Keywords: cell phenotypes; immune cell; liver diseases; inflammatory liver ... See more keywords
Annulus fibrosus cell phenotypes in homeostasis and injury: implications for regenerative strategies
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.13964
Abstract: Despite considerable efforts to develop cellular, molecular, and structural repair strategies and restore intervertebral disk function after injury, the basic biology underlying intervertebral disk healing remains poorly understood. Remarkably, little is known about the origins… read more here.
Keywords: cell phenotypes; fibrosus cell; annulus fibrosus; fibrosus ... See more keywords
Quantile-Specific Heritability of Mean Platelet Volume, Leukocyte Count, and Other Blood Cell Phenotypes
Sign Up to like & getrecommendations! Published in 2022 at "Lifestyle Genomics"
DOI: 10.1159/000527048
Abstract: Introduction: “Quantile-dependent expressivity” occurs when the effect size of a genetic variant depends upon whether the phenotype (e.g., mean platelet volume, MPV) is high or low relative to its distribution. Methods: Offspring-parent regression slopes (βOP)… read more here.
Keywords: blood; blood cell; cell phenotypes; quantile specific ... See more keywords
The difference of T cell phenotypes in end stage renal disease patients under different dialysis modality
Sign Up to like & getrecommendations! Published in 2019 at "BMC Nephrology"
DOI: 10.1186/s12882-019-1475-y
Abstract: BackgroundImpaired T cell immune function exists in end-stage renal disease (ESRD) patients. Dialysis treatment may lead to changes in T cell subsets. In the present study, we aimed to identify alterations of T cell phenotypes… read more here.
Keywords: cell phenotypes; dialysis modality; cd8 cells; cell ... See more keywords
Circulating immune cell phenotypes are associated with age, sex, CMV, and smoking status in the Framingham Heart Study offspring participants.
Sign Up to like & getrecommendations! Published in 2023 at "Aging"
DOI: 10.18632/aging.204686
Abstract: Understanding the composition of circulating immune cells with aging and the underlying biologic mechanisms driving aging may provide molecular targets to slow the aging process and reduce age-related disease. Utilizing cryopreserved cells from 996 Framingham… read more here.
Keywords: circulating immune; immune cell; cell phenotypes; age ... See more keywords
Erratum: Systemic Characterization of Novel Immune Cell Phenotypes in Recurrent Pregnancy Loss
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.722805
Abstract: [This corrects the article DOI: 10.3389/fimmu.2021.657552.]. read more here.
Keywords: characterization novel; cell phenotypes; immune cell; novel immune ... See more keywords