Deterministic Single Cell Encapsulation in Asymmetric Microenvironments to Direct Cell Polarity
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202206014
Abstract: Various signals in tissue microenvironments are often unevenly distributed around cells. Cellular responses to asymmetric cell‐matrix adhesion in a 3D space remain generally unclear and are to be studied at the single‐cell resolution. Here, the… read more here.
Keywords: cell; presentation; cell polarity; single cell ... See more keywords
Cell Polarity and Notch Signaling: Linked by the E3 Ubiquitin Ligase Neuralized?
Sign Up to like & getrecommendations! Published in 2017 at "BioEssays"
DOI: 10.1002/bies.201700128
Abstract: Notch is a mechanosensitive receptor that requires direct cell–cell contact for its activation. Both the strength and the range of notch signaling depend on the size and geometry of the contact sites between cells. These… read more here.
Keywords: cell polarity; ubiquitin ligase; polarity; notch signaling ... See more keywords
Phosphoinositides and Cell Polarity in the Drosophila Egg Chamber.
Sign Up to like & getrecommendations! Published in 2017 at "Results and problems in cell differentiation"
DOI: 10.1007/978-3-319-60855-6_8
Abstract: Phosphatidylinositol phosphates (PIPs) are essential membrane components. They are localized at distinct membrane domains and recruit distinct effectors; they play an important role in the maintenance of membrane identity. They are essential for many cellular… read more here.
Keywords: drosophila egg; polarity; egg chamber; cell polarity ... See more keywords
Quantitative methods to study epithelial morphogenesis and polarity.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in cell biology"
DOI: 10.1016/bs.mcb.2016.12.004
Abstract: Morphogenesis of an epithelial tissue emerges from the behavior of its constituent cells, including changes in shape, rearrangements, and divisions. In many instances the directionality of these cellular events is controlled by the polarized distribution of… read more here.
Keywords: cell polarity; morphogenesis polarity; microscopy; morphogenesis ... See more keywords
Establishing and transducing cell polarity: common themes and variations.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2017.10.007
Abstract: All cells in vivo have a primary axis of polarity that controls many aspects of their behaviour, such as the direction of protein secretion and signalling, the orientation of cell division and directed cell movement… read more here.
Keywords: cell polarity; establishing transducing; transducing cell; polarity ... See more keywords
The Actin Nucleator Cobl Is Critical for Centriolar Positioning, Postnatal Planar Cell Polarity Refinement, and Function of the Cochlea.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.07.087
Abstract: Proper cochlear hair cell array development and sensory apparatus positioning are achieved by planar cell polarity signaling. Effectors executing proper tissue development and maturation programs are largely unknown. We show that the actin nucleator Cobl… read more here.
Keywords: cell polarity; planar cell; polarity; cobl ... See more keywords
Shank2 Binds to aPKC and Controls Tight Junction Formation with Rap1 Signaling during Establishment of Epithelial Cell Polarity.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.02.088
Abstract: Epithelial cells establish apicobasal polarity by forming tight junctions (TJs) at the apical-lateral boundary, which play fundamental roles in physiological functions. An evolutionarily conserved atypical protein kinase C (aPKC)-partitioning defective (PAR) complex functions as a… read more here.
Keywords: cell polarity; polarity; rap1; shank2 binds ... See more keywords
Ectopic BASL Reveals Tissue Cell Polarity throughout Leaf Development in Arabidopsis thaliana
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DOI: 10.1016/j.cub.2018.06.019
Abstract: Summary Tissue-wide polarity fields, in which cell polarity is coordinated across the tissue, have been described for planar organs such as the Drosophila wing and are considered important for coordinating growth and differentiation [1]. In… read more here.
Keywords: polarity field; basl; cell polarity; tissue ... See more keywords
The Scribble Cell Polarity Module in the Regulation of Cell Signaling in Tissue Development and Tumorigenesis.
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DOI: 10.1016/j.jmb.2018.01.011
Abstract: The Scribble cell polarity module, comprising Scribbled (Scrib), Discs-large (Dlg) and Lethal-2-giant larvae (Lgl), has a tumor suppressive role in mammalian epithelial cancers. The Scribble module proteins play key functions in the establishment and maintenance… read more here.
Keywords: cell polarity; module; tissue; cell ... See more keywords
Polarized Organization of the Cytoskeleton: Regulation by Cell Polarity Proteins.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2018.06.028
Abstract: Polarity is one of the fundamental properties displayed by living organisms. In metazoans, cell polarity governs developmental processes and plays an essential role during maintenance of forms of tissues as well as their functions. The… read more here.
Keywords: cell polarity; polarity modules; polarity; organization cytoskeleton ... See more keywords
The regulation of cell polarity and organ positioning in plants
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.182
Abstract: The current proposal aims to investigate the mechanisms by which two steroids, pregnenolone (P5) and progesterone (P4) affect zebrafish embryo development. We showed that pregnenolone promoted cell migration, while progesterone was involved in cell patterning.… read more here.
Keywords: cell polarity; regulation cell; organ positioning; hsd3b2 ... See more keywords