Cell-ECM contact-guided intracellular polarization is mediated via lamin A/C dependent nucleus-cytoskeletal connection.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120548
Abstract: Cell polarization plays a crucial role in dynamic cellular events, such as cell proliferation, differentiation, and directional migration in response to diverse extracellular and intracellular signals. Although it is well known that cell polarization entails… read more here.
Keywords: polarization; cell polarization; nucleus cytoskeletal; intracellular polarization ... See more keywords
Does Cell Polarization Matter in Single-Ion Conducting Electrolytes?
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c19097
Abstract: Single-ion conducting polymer electrolytes (SIPE) are particularly promising electrolyte materials in lithium metal-based batteries since theoretical considerations suggest that the immobilization of anions avoids polarization phenomena at electrode|electrolyte interfaces. SIPE in principle could allow for… read more here.
Keywords: polarization; ion conducting; polarization matter; cell polarization ... See more keywords
Lactate modulates CD4+ T-cell polarization and induces an immunosuppressive environment, which sustains prostate carcinoma progression via TLR8/miR21 axis
Sign Up to like & getrecommendations! Published in 2019 at "Oncogene"
DOI: 10.1038/s41388-019-0688-7
Abstract: Leukocyte infiltration plays an active role in controlling tumor development. In the early stages of carcinogenesis, T cells counteract tumor growth. However, in advanced stages, cancer cells and infiltrating stromal components interfere with the immune… read more here.
Keywords: lactate; cell polarization; cancer; cell ... See more keywords
Pplase of Dermatophagoides farinae promotes ovalbumin-induced airway allergy by modulating the functions of dendritic cells in a mouse model
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep43322
Abstract: Our previous studies revealed that many proteins in addition to the known allergens of D. farinae have not been fully characterized. We observed that Pplase did not respond to serum collected from patients sensitized to… read more here.
Keywords: pplase dermatophagoides; pplase; model pplase; cell polarization ... See more keywords
Influence of myosin activity and mechanical impact on keratocyte polarization.
Sign Up to like & getrecommendations! Published in 2020 at "Soft matter"
DOI: 10.1039/d0sm00473a
Abstract: In cell migration, polarization is the process by which a stationary cell breaks symmetry and initiates motion. Although a lot is known about the mechanisms involved in cell polarization, the role played by myosin contraction… read more here.
Keywords: mechanical impact; influence myosin; polarization; cell polarization ... See more keywords
Laminins in Epithelial Cell Polarization: Old Questions in Search of New Answers.
Sign Up to like & getrecommendations! Published in 2017 at "Cold Spring Harbor perspectives in biology"
DOI: 10.1101/cshperspect.a027920
Abstract: Laminin, a basement membrane protein discovered in 1979, was shortly thereafter implicated in the polarization of epithelial cells in both mammals and a variety of lower organisms. To transduce a spatial cue to the intrinsic… read more here.
Keywords: epithelial cell; laminins epithelial; old questions; polarization ... See more keywords
NNVA: Neural Network Assisted Visual Analysis of Yeast Cell Polarization Simulation
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Transactions on Visualization and Computer Graphics"
DOI: 10.1109/tvcg.2019.2934591
Abstract: Complex computational models are often designed to simulate real-world physical phenomena in many scientific disciplines. However, these simulation models tend to be computationally very expensive and involve a large number of simulation input parameters, which… read more here.
Keywords: visual analysis; cell polarization; analysis; parameter ... See more keywords
DC Metabolism Controls Lung T Cell Polarization
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Transplantation"
DOI: 10.1111/ajt.14648
Abstract: Following intense interest in the transcription factors that program differentiation and effector function of immune cells, the immunology community is now embracing the importance of cell metabolism in these processes. The mechanistic target of rapamycin,… read more here.
Keywords: metabolism; cell polarization; mtor; differentiation ... See more keywords
T‐cell polarization differs in various stages of discoid lupus erythematosus skin
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Dermatology"
DOI: 10.1111/bjd.18704
Abstract: The clinical presentation and pathology of discoid lupus erythematosus (DLE) varies by stage. Erythematous scaly papules and plaques characterize the early lesions. They progress to dyspigmented patches and plaques with central scarring and atrophy. Under… read more here.
Keywords: differs various; discoid lupus; lupus erythematosus; cell polarization ... See more keywords
Der p 2.1 Peptide Abrogates House Dust Mites-Induced Asthma Features in Mice and Humanized Mice by Inhibiting DC-Mediated T Cell Polarization
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.565431
Abstract: Asthma is a chronic airway disease often due to sensitization to aeroallergens, especially house dust mite allergens (HDMs). The Dermatophagoides pteronyssinus group 2 (Der p 2), is one of the most representative HDM allergens and… read more here.
Keywords: humanized mice; cell polarization; mice humanized; der ... See more keywords
High-Dose Cyclophosphamide Administration Orchestrates Phenotypic and Functional Alterations of Immature Dendritic Cells and Regulates Th Cell Polarization
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.00775
Abstract: High-dose cyclophosphamide (CTX) inhibits the immune response. Dendritic cells (DCs) are professional antigen presenting cells (APCs) with a crucial role in initiating immune responses and sustaining immune tolerance. The relative contribution of DCs to immunosuppression… read more here.
Keywords: dose cyclophosphamide; high dose; polarization; dendritic cells ... See more keywords