IKAROS expression in distinct bone marrow cell populations as a candidate biomarker for outcome with lenalidomide‐dexamethasone therapy in multiple myeloma
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Hematology"
DOI: 10.1002/ajh.24634
Abstract: Immunomodulatory drugs (IMiDs) are a cornerstone in the treatment of multiple myeloma (MM), but specific markers to predict outcome are still missing. Recent work pointed to a prognostic role for IMiD target genes (e.g. CRBN).… read more here.
Keywords: cell populations; multiple myeloma; expression; lenalidomide dexamethasone ... See more keywords
Anatomical projections to the dorsal tegmental nucleus and abducens nucleus arise from separate cell populations in the nucleus prepositus hypoglossi, but overlapping cell populations in the medial vestibular nucleus
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25119
Abstract: Specialized circuitry in the brain processes spatial information to provide a sense of direction used for navigation. The dorsal tegmental nucleus (DTN) is a core component of this circuitry and utilizes vestibular inputs to generate… read more here.
Keywords: nucleus; cell populations; tegmental nucleus; dtn ... See more keywords
DAFi: A directed recursive data filtering and clustering approach for improving and interpreting data clustering identification of cell populations from polychromatic flow cytometry data
Sign Up to like & getrecommendations! Published in 2018 at "Cytometry Part A"
DOI: 10.1002/cyto.a.23371
Abstract: Computational methods for identification of cell populations from polychromatic flow cytometry data are changing the paradigm of cytometry bioinformatics. Data clustering is the most common computational approach to unsupervised identification of cell populations from multidimensional… read more here.
Keywords: cell; cell populations; dafi; data clustering ... See more keywords
Global koff‐rates of polyclonal T‐cell populations merge subclonal avidities and predict functionality
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149597
Abstract: The avidity of TCRs for peptide‐major histocompatibility complexes (pMHCs) is a governing factor in how T cells respond to antigen. TCR avidity is generally linked to T‐cell functionality and there is growing evidence for distinct… read more here.
Keywords: cell; cell populations; koff rates; avidity ... See more keywords
Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250254
Abstract: Enterotoxigenic Escherichia coli (ETEC) is an important cause of children's and travelers' diarrhea, with no licensed vaccine. This study aimed to explore the role of cellular immunity in protection against human ETEC infection. Nine volunteers… read more here.
Keywords: cell; cd4 th17; escherichia coli; cell populations ... See more keywords
Messenger RNA Sequencing of Rare Cell Populations in the Lung and Lung-Draining Lymph Nodes.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6786-5_14
Abstract: Next-generation sequencing (NGS) techniques provide unique prospects for in-depth transcriptome analyses. Nevertheless, the emerging and still growing knowledge about the large diversity and heterogeneity of cells that participate in immunological responses in a tissue- and… read more here.
Keywords: populations lung; cell populations; transcriptome analyses; cell ... See more keywords
Quantitative Measurement of Cholesterol in Cell Populations Using Flow Cytometry and Fluorescent Perfringolysin O.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6875-6_8
Abstract: Methods to quantify intracellular cholesterol are valuable for the study of its trafficking and storage in normal cells and in lysosomal storage disorders. Traditionally, cholesterol has been tracked using the small molecule, filipin. Filipin can… read more here.
Keywords: perfringolysin; quantitative measurement; cell populations; measurement cholesterol ... See more keywords
Quantitation and chemical coding of enteroendocrine cell populations in the human jejunum
Sign Up to like & getrecommendations! Published in 2019 at "Cell and Tissue Research"
DOI: 10.1007/s00441-019-03099-3
Abstract: Recent studies reveal substantial species and regional differences in enteroendocrine cell (EEC) populations, including differences in patterns of hormone coexpression, which limit extrapolation between animal models and human. In this study, jejunal samples, with no… read more here.
Keywords: cell populations; human jejunum; enteroendocrine cell; cell ... See more keywords
A fixed cytometer chip for identification of cell populations and real-time monitoring of single-cell apoptosis under gradient UV radiation
Sign Up to like & getrecommendations! Published in 2019 at "Microfluidics and Nanofluidics"
DOI: 10.1007/s10404-019-2244-8
Abstract: Cytometry is a basic method to determine cell populations and morphology. Flow cytometry and hemocytometry are the two most common methods among cytometric technologies. However, flow cytometry needs bulky and expensive equipment as well as… read more here.
Keywords: time monitoring; real time; cell populations; cell ... See more keywords
Exosome-mediated Bidirectional Signaling between Mesenchymal Stem Cells and Chondrocytes for Enhanced Chondrogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Bioprocess Engineering"
DOI: 10.1007/s12257-019-0332-y
Abstract: Exosomes of human mesenchymal stem cells (hMSC) are known to effectively increase the proliferation rate of chondrocytes and stimulate cartilage extracellular matrix. However, the therapeutic efficacy of the other signaling direction (i.e., the effect of… read more here.
Keywords: cell populations; stem cells; exosome mediated; mesenchymal stem ... See more keywords
T lymphocyte responses to flaviviruses - diverse cell populations affect tendency toward protection and disease.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in virology"
DOI: 10.1016/j.coviro.2020.07.008
Abstract: Dengue virus (DENV), Yellow Fever virus, West Nile virus, Japanese encephalitis virus and Zika virus are medically important flaviviruses transmitted to humans by mosquitoes and circulate in overlapping geographic areas. Cross-reactive immune responses have been… read more here.
Keywords: flaviviruses diverse; responses flaviviruses; cell populations; lymphocyte responses ... See more keywords