Restriction point regulation at the crossroads between quiescence and cell proliferation
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13867
Abstract: The coordination of cell proliferation with reversible cell cycle exit into quiescence is crucial for the development of multicellular organisms and for tissue homeostasis in the adult. The decision between quiescence and proliferation occurs at… read more here.
Keywords: cell proliferation; point; restriction point;
The deubiquitinating enzyme USP17 regulates c‐Myc levels and controls cell proliferation and glycolysis
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14296
Abstract: The c‐Myc oncoprotein is frequently overexpressed in human cancers and is essential for cancer cell proliferation. The dysregulation of ubiquitin‐proteasome‐mediated degradation is one of the contributing factors to the upregulated expression of c‐Myc in human… read more here.
Keywords: myc levels; proliferation glycolysis; cell proliferation; proliferation ... See more keywords
LIM protein Ajuba promotes liver cell proliferation through its involvement in DNA replication and DNA damage control
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14371
Abstract: The LIM‐domain protein Ajuba is associated with cell proliferation, a fundamental process of tissue regeneration and cancer. We report that in the liver, Ajuba expression is increased during regeneration and in tumour cells and tissues.… read more here.
Keywords: dna; cell proliferation; damage; ajuba ... See more keywords
CCDC115 inhibits autophagy‐mediated degradation of YAP to promote cell proliferation
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14575
Abstract: Autophagy and Hippo signalling pathways both play important roles in cell homeostasis and are often involved in tumourigenesis. However, the crosstalk between these two signal pathways in response to stress conditions, such as nutrient deficiency,… read more here.
Keywords: cell proliferation; inhibits autophagy; yap; ccdc115 inhibits ... See more keywords
KSR induces RAS‐independent MAPK pathway activation and modulates the efficacy of KRAS inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13213
Abstract: The kinase suppressor of rat sarcoma (RAS) proteins (KSR1 and KSR2) have long been considered as scaffolding proteins required for optimal mitogen‐activated protein kinase (MAPK) pathway signalling. However, recent evidence suggests that they play a… read more here.
Keywords: mapk pathway; mapk; cell proliferation;
MiR‐409‐3p regulates cell proliferation and tumor growth by targeting E74‐like factor 2 in osteosarcoma
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12177
Abstract: Recent evidence has shown that miR‐409‐3p was down‐regulated in several types of cancer, including osteosarcoma. However, the potential role of miR‐409‐3p in osteosarcoma remains largely unknown. In the present study, we showed that overexpression of… read more here.
Keywords: cell proliferation; mir 409; osteosarcoma; tumor growth ... See more keywords
Large‐Scale Nanophotonic Structures for Long‐Term Monitoring of Cell Proliferation
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Biosystems"
DOI: 10.1002/adbi.201700258
Abstract: Innovative sensing materials have enabled the discovery of cell biology principles at the nanoscale. In order to evaluate cell behavior and responses, it is necessary to accurately monitor cell proliferation. However, it remains challenging to… read more here.
Keywords: cell proliferation; long term; proliferation; cell ... See more keywords
PRMT5 Maintains Homeostasis of the Intestinal Epithelium by Modulating Cell Proliferation and Survival
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202415559
Abstract: Intestinal homeostasis is sustained by self‐renewal of intestinal stem cells, which continuously divide and produce proliferative transit‐amplifying (TA) and progenitor cells. Protein arginine methyltransferases 5 (PRMT5) plays a crucial role in regulating homeostasis of various… read more here.
Keywords: cell; intestinal epithelium; cell proliferation; prmt5 ... See more keywords
Phosphorylation‐Dependent Stabilization of Collaborator of ARF (CARF) Suppresses Lymphoma Cell Proliferation
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202416687
Abstract: Uncontrolled cell proliferation drives tumorigenesis and malignant progression, making cell cycle regulation a promising strategy for cancer therapy. Phosphorylation plays pivotal roles in cancer initiation and metastasis by regulating the cancer‐related proteins. Identifying key phosphorylation… read more here.
Keywords: phosphorylation; cell proliferation; cell; lymphoma cell ... See more keywords
K29‐Linked Ubiquitination of Transcription Regulators Controls Cell Proliferation in the Unfolded Protein Response
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DOI: 10.1002/advs.202509817
Abstract: The ubiquitin chains perform diverse biological functions through different linkages. However, the understanding of non‐canonical K29‐linked ubiquitin chains is relatively limited. Exploring the physiological functions of K29‐linked ubiquitin chains beyond degradation is crucial for deciphering… read more here.
Keywords: k29 linked; cell proliferation; k29; linked ubiquitination ... See more keywords
Human platelet lysate supports SH‐SY5Y neuroblastoma cell proliferation and differentiation into a dopaminergic‐like neuronal phenotype under xenogeneic‐free culture conditions
Sign Up to like & getrecommendations! Published in 2024 at "Biotechnology Journal"
DOI: 10.1002/biot.202400068
Abstract: SH‐SY5Y is a human neuroblastoma cell line that can be differentiated into several neuronal phenotypes, depending on culture conditions. For this reason, this cell line has been widely used as an in vitro model of… read more here.
Keywords: differentiation; cell proliferation; culture; sy5y ... See more keywords