Restriction point regulation at the crossroads between quiescence and cell proliferation
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DOI: 10.1002/1873-3468.13867
Abstract: The coordination of cell proliferation with reversible cell cycle exit into quiescence is crucial for the development of multicellular organisms and for tissue homeostasis in the adult. The decision between quiescence and proliferation occurs at… read more here.
Keywords: cell proliferation; point; restriction point;
The deubiquitinating enzyme USP17 regulates c‐Myc levels and controls cell proliferation and glycolysis
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14296
Abstract: The c‐Myc oncoprotein is frequently overexpressed in human cancers and is essential for cancer cell proliferation. The dysregulation of ubiquitin‐proteasome‐mediated degradation is one of the contributing factors to the upregulated expression of c‐Myc in human… read more here.
Keywords: myc levels; proliferation glycolysis; cell proliferation; proliferation ... See more keywords
LIM protein Ajuba promotes liver cell proliferation through its involvement in DNA replication and DNA damage control
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14371
Abstract: The LIM‐domain protein Ajuba is associated with cell proliferation, a fundamental process of tissue regeneration and cancer. We report that in the liver, Ajuba expression is increased during regeneration and in tumour cells and tissues.… read more here.
Keywords: dna; cell proliferation; damage; ajuba ... See more keywords
CCDC115 inhibits autophagy‐mediated degradation of YAP to promote cell proliferation
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14575
Abstract: Autophagy and Hippo signalling pathways both play important roles in cell homeostasis and are often involved in tumourigenesis. However, the crosstalk between these two signal pathways in response to stress conditions, such as nutrient deficiency,… read more here.
Keywords: cell proliferation; inhibits autophagy; yap; ccdc115 inhibits ... See more keywords
KSR induces RAS‐independent MAPK pathway activation and modulates the efficacy of KRAS inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13213
Abstract: The kinase suppressor of rat sarcoma (RAS) proteins (KSR1 and KSR2) have long been considered as scaffolding proteins required for optimal mitogen‐activated protein kinase (MAPK) pathway signalling. However, recent evidence suggests that they play a… read more here.
Keywords: mapk pathway; mapk; cell proliferation;
MiR‐409‐3p regulates cell proliferation and tumor growth by targeting E74‐like factor 2 in osteosarcoma
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DOI: 10.1002/2211-5463.12177
Abstract: Recent evidence has shown that miR‐409‐3p was down‐regulated in several types of cancer, including osteosarcoma. However, the potential role of miR‐409‐3p in osteosarcoma remains largely unknown. In the present study, we showed that overexpression of… read more here.
Keywords: cell proliferation; mir 409; osteosarcoma; tumor growth ... See more keywords
Large‐Scale Nanophotonic Structures for Long‐Term Monitoring of Cell Proliferation
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Biosystems"
DOI: 10.1002/adbi.201700258
Abstract: Innovative sensing materials have enabled the discovery of cell biology principles at the nanoscale. In order to evaluate cell behavior and responses, it is necessary to accurately monitor cell proliferation. However, it remains challenging to… read more here.
Keywords: cell proliferation; long term; proliferation; cell ... See more keywords
Tescalcin is an unfavorable prognosis factor that regulats cell proliferation and survival in hepatocellular carcinoma patients
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Communications"
DOI: 10.1002/cac2.12069
Abstract: Abstract Background Hepatocellular carcinoma (HCC) is a major health problem and a primary cause of cancer‐related death worldwide. Although great advances have achieved recently by large‐scale high‐throughput analysis, the precise molecular mechanism underlying HCC progression… read more here.
Keywords: cell proliferation; tesc; factor; hcc ... See more keywords
p62/sequestosome 1 in human colorectal carcinoma as a potent prognostic predictor associated with cell proliferation
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Medicine"
DOI: 10.1002/cam4.1093
Abstract: p62/sequestosome 1 (p62) is a multi‐domain protein that functions as a receptor for ubiquitinated targets in the selective autophagy and serves as a scaffold in various signaling cascades. p62 have been reported to be up‐regulated… read more here.
Keywords: cell proliferation; p62; colorectal carcinoma;
LncRNA LUCAT1 contributes to cell proliferation and migration in human pancreatic ductal adenocarcinoma via sponging miR‐539
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2724
Abstract: Pancreatic ductal adenocarcinoma is one of the most aggressive and dreadful malignancies worldwide. Long noncoding RNAs (lncRNAs) have emerged as vital regulators in the development of human malignancies and other disorders. This study aimed to… read more here.
Keywords: cell proliferation; lncrna lucat1; cell; pdac ... See more keywords
circITCH suppresses cell proliferation and metastasis through miR‐660/TFCP2 pathway in melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4627
Abstract: Melanoma is an aggressive disease that is rising in incidence. Advanced melanoma is still a life‐threatening disease. CircRNAs are documented to be involved in melanoma progression. But circITCH role in melanoma remains unclear. read more here.
Keywords: circitch; cell proliferation; melanoma; proliferation metastasis ... See more keywords