Delineation of clinical course, outcomes, and prognostic factors in patients with T‐cell prolymphocytic leukemia
Sign Up to like & getrecommendations! Published in 2023 at "American Journal of Hematology"
DOI: 10.1002/ajh.26918
Abstract: T‐cell prolymphocytic leukemia (T‐PLL) is a rare, post‐thymic T‐cell neoplasm with a diverse clinical course. T‐PLL is typically associated with a poor prognosis; however, a subset of patients have inactive disease on initial presentation. There… read more here.
Keywords: prognostic factors; disease; clinical course; course ... See more keywords
CD161 Is Expressed in a Subset of T-Cell Prolymphocytic Leukemia Cases and Is Useful for Disease Follow-up.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqz060
Abstract: OBJECTIVES CD161 (NKRP1) is a lectin-like receptor present on NK cells and rare T-cell subsets. We have observed CD161 expression in some cases of T-cell prolymphocytic leukemia (T-PLL) and found it to be useful in… read more here.
Keywords: cd161; disease; cell prolymphocytic; prolymphocytic leukemia ... See more keywords
Concomitant T-cell prolymphocytic leukemia and visceral leishmaniasis
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000012410
Abstract: Rationale: T-cell prolymphocytic leukaemia (T-PLL) is a rare aggressive lymphoid disease featured by a significant increased lymphocyte count and obvious hepatosplenomegaly with poor prognosis. The concomitant presentation of T-PLL and visceral leishmaniasis (VL) has not… read more here.
Keywords: cell prolymphocytic; concomitant cell; visceral leishmaniasis; concomitant ... See more keywords
Comparison of clinicopathological characteristics between T‐cell prolymphocytic leukemia and peripheral T‐cell lymphoma, not otherwise specified
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Haematology"
DOI: 10.1111/ejh.12856
Abstract: T‐cell prolymphocytic leukemia (T‐PLL) is a very rare, aggressive T‐cell neoplasm. Peripheral T‐cell lymphoma, not otherwise specified (PTCL‐NOS) is also a highly aggressive lymphoma. These two diseases can often be confused with each other; therefore,… read more here.
Keywords: lymphoma; cell prolymphocytic; prolymphocytic leukemia; cell ... See more keywords
Mutations in PIGA cause a CD52‐/GPI‐anchor‐deficient phenotype complicating alemtuzumab treatment in T‐cell prolymphocytic leukemia
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Haematology"
DOI: 10.1111/ejh.13511
Abstract: Infusional alemtuzumab followed by consolidating allogeneic hematopoietic stem cell transplantation in eligible patients is considered a standard of care in T‐cell prolymphocytic leukemia (T‐PLL). Antibody selection against CD52 has been associated with the development of… read more here.
Keywords: cd52; cell prolymphocytic; mutations piga; prolymphocytic leukemia ... See more keywords
Generalized pruritic dark papules in a patient with T‐cell prolymphocytic leukemia – a clinicopathological challenge
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Dermatology"
DOI: 10.1111/ijd.14642
Abstract: A 48-year-old man presented with multiple pruritic dark red papules for 9 months. The lesions started on his hands and subsequently spread to the trunk and limbs within the last 2 months. He also had… read more here.
Keywords: pruritic dark; blood; cell prolymphocytic; prolymphocytic leukemia ... See more keywords
T-cell prolymphocytic leukaemia associated with immune checkpoint inhibitor (pembrolizumab)
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-245603
Abstract: We describe the case of a man in his 60s with squamous cell carcinoma of the lung with brain metastasis treated with pembrolizumab who subsequently developed T-cell prolymphocytic leukaemia. He was transferred to our hospital… read more here.
Keywords: cell; immune checkpoint; checkpoint; cell prolymphocytic ... See more keywords
Comparison of karyotyping, TCL1 fluorescence in situ hybridisation and TCL1 immunohistochemistry in T cell prolymphocytic leukaemia
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2017-204616
Abstract: Aims T cell prolymphocytic leukaemia (T-PLL) is defined as an aggressive T cell leukaemia composed of small to medium-sized lymphocytes with a mature T cell immunophenotype. Most of these cases are known to be associated… read more here.
Keywords: tcl1 rearrangement; prolymphocytic leukaemia; tcl1; cell prolymphocytic ... See more keywords
Non-canonical function of AGO2 augments T-cell receptor signaling in T-cell prolymphocytic leukemia.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-21-1908
Abstract: T-cell prolymphocytic leukemia (T-PLL) is a chemotherapy-refractory T-cell malignancy with limited therapeutic options and a poor prognosis. Current disease concepts implicate TCL1A oncogene-mediated enhanced T-cell receptor (TCR) signaling and aberrant DNA repair as central perturbed… read more here.
Keywords: cell; ago2; non canonical; cell prolymphocytic ... See more keywords
Recurrence of T-Cell Prolymphocytic Leukemia With a Rare Presentation as Diffuse Generalized Skin Lesion
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Investigative Medicine High Impact Case Reports"
DOI: 10.1177/23247096231176223
Abstract: T-cell prolymphocytic leukemia (T-PLL) is a rare and aggressive neoplasm that originates from mature post-thymic T-cells. Cutaneous manifestations are a common presentation in T-PLL but rarely are a presentation in the recurrent setting. Here, we… read more here.
Keywords: prolymphocytic leukemia; pll; cell prolymphocytic; diffuse ... See more keywords
T-cell prolymphocytic leukemia negative for surface CD3 and CD45.
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-03-840611
Abstract: ![Figure][1] A 75-year-old man was referred to us with an outside diagnosis of T-cell prolymphocytic leukemia (T-PLL) posttreatment. He had mild leukocytosis (white blood cell count, 11.5 × 109/L) and multicompartmental lymphadenopathy by positron emission… read more here.
Keywords: cell; negative surface; cell prolymphocytic; prolymphocytic leukemia ... See more keywords