Articles with "cell protease" as a keyword



Identification of SARS-CoV-2 inhibitors targeting Mpro and PLpro using in-cell-protease assay

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Published in 2022 at "Communications Biology"

DOI: 10.1038/s42003-022-03090-9

Abstract: SARS-CoV-2 proteases Mpro and PLpro are promising targets for antiviral drug development. In this study, we present an antiviral screening strategy involving a novel in-cell protease assay, antiviral and biochemical activity assessments, as well as… read more here.

Keywords: cell protease; sars cov; protease; mpro plpro ... See more keywords