Ultrasound‐Amplified Enzyodynamic Tumor Therapy by Perovskite Nanoenzyme‐Enabled Cell Pyroptosis and Cascade Catalysis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202208817
Abstract: Overcoming apoptosis resistance to achieve efficient breast cancer treatment remains a challenge. The precise induction of another form of programmed cell death, pyroptosis, is an excellent alternative for treating cancer. Ultrasound (US)‐enhanced enzyme dynamic (enzyodynamic)… read more here.
Keywords: cell; pyroptosis; therapy; ultrasound amplified ... See more keywords
Inherent Capability of Self-Assembling Nanostructures in Specific Proteasome Activation for Cancer Cell Pyroptosis.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202205531
Abstract: Understanding the direct interaction of nanostructures per se with biological systems is important for biomedical applications. However, whether nanostructures regulate biological systems by targeting specific cellular proteins remains largely unknown. In the present work, self-assembling… read more here.
Keywords: cell; cell pyroptosis; self assembling; cancer cell ... See more keywords
The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury.
Sign Up to like & getrecommendations! Published in 2019 at "Kidney international"
DOI: 10.1016/j.kint.2019.04.035
Abstract: Inflammation and tubular cell death are the hallmarks of acute kidney injury (AKI). However, the precise mechanism underlying these effects has not been fully elucidated. Here we tested whether caspase-11, an inflammatory member of the… read more here.
Keywords: cell pyroptosis; caspase; urinary excretion; cell ... See more keywords
MiR-192 attenuates high glucose-induced pyroptosis in retinal pigment epithelial cells via inflammasome modulation.
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2044734
Abstract: Diabetic retinopathy is one of the most characteristic complications of diabetes mellitus, and pyroptosis plays acrucial role in the onset and development of diabetic retinopathy. Although microRNA-192 (miR-192) has been demonstrated to be involved in… read more here.
Keywords: mir 192; cell pyroptosis; pyroptosis retinal; pyroptosis ... See more keywords
A3067 Eplerenone inhibits the cell pyroptosis in contralateral kidney of UUO rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548095.91094.dd
Abstract: Objectives: To investigate the inhibitory effect of eplerenone, an aldosterone receptor blocker, on cell pyroptosis in contralateral kidney of UUO rats, and to elucidate the role of aldosterone in the process of unilateral renal injury-induced… read more here.
Keywords: uuo rats; contralateral kidney; eplerenone; kidney uuo ... See more keywords
Melatonin prevents endothelial cell pyroptosis via regulation of long noncoding RNA MEG3/miR‐223/NLRP3 axis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pineal Research"
DOI: 10.1111/jpi.12449
Abstract: Atherosclerosis (AS) is an inflammatory disease linked to endothelial dysfunction. Melatonin is reported to possess substantial anti‐inflammatory properties, which has proven to be effective in AS. Emerging literature suggests that pyroptosis plays a critical role… read more here.
Keywords: meg3; pyroptosis; endothelial cell; mir 223 ... See more keywords
Pectic polysaccharides derived from Hainan Rauwolfia ameliorates NLRP3-mediated colonic epithelial cell pyroptosis in ulcerative colitis.
Sign Up to like & getrecommendations! Published in 2022 at "Physiological genomics"
DOI: 10.1152/physiolgenomics.00081.2022
Abstract: Pectic polysaccharides (PP) could exert functions on ulcerative colitis (UC), which is classified as a non-specific inflammatory disorder. This study investigated the molecular mechanism of PP derived from Rauwolfia in UC. Firstly, the dextran sodium… read more here.
Keywords: colonic epithelial; pyroptosis; cell pyroptosis; epithelial cell ... See more keywords
Downregulation of miR-137 Facilitates CD4+ T Cell Pyroptosis in Systemic Lupus Erythematosus via Stimulating AMPK Pathway
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Immunology Research"
DOI: 10.1155/2023/1241774
Abstract: Objective From the pathogenic mechanism point of view, systemic lupus erythematosus (SLE) features prominently in T lymphocyte apoptosis. Yet the regulatory mechanism underlying SLE cell apoptosis remains to be explored. This research intends to clarify… read more here.
Keywords: cell; cd4 cells; cd4 cell; mir 137 ... See more keywords
Eplerenone Ameliorates Cell Pyroptosis in Contralateral Kidneys of Rats with Unilateral Ureteral Obstruction
Sign Up to like & getrecommendations! Published in 2019 at "Nephron"
DOI: 10.1159/000497489
Abstract: Background: The progression of chronic renal failure in patients with unilateral renal injury is associated with loss of function in the contralateral kidney, but the molecular mechanism remains unclear. The activation of mineralocorticoid receptor (MR)… read more here.
Keywords: unilateral ureteral; ureteral obstruction; pyroptosis; contralateral kidneys ... See more keywords
Interleukin-37 protects against acinar cell pyroptosis in acute pancreatitis
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DOI: 10.1172/jci.insight.161244
Abstract: Acute pancreatitis (AP) is a local and/or systemic inflammatory disease that starts with acinar cell injury and necrosis; it has no effective medical treatment and thus remains a life-threatening condition. Interleukin-37 (IL-37), a natural immunomodulator,… read more here.
Keywords: pyroptosis; protects acinar; acinar cell; acute pancreatitis ... See more keywords
Sodium Tanshinone IIA Sulfonate Inhibits Vascular Endothelial Cell Pyroptosis via the AMPK Signaling Pathway in Atherosclerosis
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DOI: 10.2147/jir.s386470
Abstract: Introduction Atherosclerosis (AS) is the underlying cause of cardiovascular events. Endothelial cell mitochondrial damage and pyroptosis are important factors contributing to AS. Changes in internal mitochondrial conformation and increase in reactive oxygen species (ROS) lead… read more here.
Keywords: cell; tanshinone iia; pyroptosis; ampk ... See more keywords