Ultrasound‐Amplified Enzyodynamic Tumor Therapy by Perovskite Nanoenzyme‐Enabled Cell Pyroptosis and Cascade Catalysis
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202208817
Abstract: Overcoming apoptosis resistance to achieve efficient breast cancer treatment remains a challenge. The precise induction of another form of programmed cell death, pyroptosis, is an excellent alternative for treating cancer. Ultrasound (US)‐enhanced enzyme dynamic (enzyodynamic)… read more here.
Keywords: cell; pyroptosis; therapy; ultrasound amplified ... See more keywords
2D Indium‐Vacancy‐Rich ZnIn2S4 Nanocatalysts for Sonocatalytic Cancer Suppression by Boosting Cancer‐Cell Pyroptosis
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Materials"
DOI: 10.1002/adma.202414432
Abstract: Sonocatalytic therapy is gaining interest for its non‐invasive nature, precise control, and excellent tissue penetration, making it a promising approach for treating malignant tumors. While defect engineering enhances electron and hole separation to boost reactive… read more here.
Keywords: indium vacancy; cancer; znin2s4; cell pyroptosis ... See more keywords
Caspase‐6/Gasdermin C‐Mediated Tumor Cell Pyroptosis Promotes Colorectal Cancer Progression Through CXCL2‐Dependent Recruitment of Myeloid‐Derived Suppressor Cells
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202411375
Abstract: Gasdermin (GSDM) family proteins mediate inflammatory cell pyroptosis and exert critical contributions to the pathogenesis of gastrointestinal cancers, infections, and gut mucosal inflammation. Gasdermin C (GSDMC) is overexpressed in human colorectal cancer (CRC); however, the… read more here.
Keywords: cell pyroptosis; pyroptosis; gasdermin; crc ... See more keywords
Inherent Capability of Self-Assembling Nanostructures in Specific Proteasome Activation for Cancer Cell Pyroptosis.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202205531
Abstract: Understanding the direct interaction of nanostructures per se with biological systems is important for biomedical applications. However, whether nanostructures regulate biological systems by targeting specific cellular proteins remains largely unknown. In the present work, self-assembling… read more here.
Keywords: cell; cell pyroptosis; self assembling; cancer cell ... See more keywords
Globular adiponectin induces esophageal adenocarcinoma cell pyroptosis via the miR‐378a‐3p/UHRF1 axis
Sign Up to like & getrecommendations! Published in 2024 at "Environmental Toxicology"
DOI: 10.1002/tox.24266
Abstract: Antiapoptosis is a major factor in the resistance of tumor cells to chemotherapy and radiotherapy. Thus, activation of cell pyroptosis may be an effective option to deal with antiapoptotic cancers such as esophageal adenocarcinoma (EAC). read more here.
Keywords: adiponectin induces; cell pyroptosis; esophageal adenocarcinoma; induces esophageal ... See more keywords
The cleavage of gasdermin D by caspase-11 promotes tubular epithelial cell pyroptosis and urinary IL-18 excretion in acute kidney injury.
Sign Up to like & getrecommendations! Published in 2019 at "Kidney international"
DOI: 10.1016/j.kint.2019.04.035
Abstract: Inflammation and tubular cell death are the hallmarks of acute kidney injury (AKI). However, the precise mechanism underlying these effects has not been fully elucidated. Here we tested whether caspase-11, an inflammatory member of the… read more here.
Keywords: cell pyroptosis; caspase; urinary excretion; cell ... See more keywords
Smart and Noninvasive SERS Immunosensors for Monitoring Dynamic Expression of Cytokines during Cell Pyroptosis.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.4c05539
Abstract: Accompanying the occurrence of inflammatory reaction to release cytokines, pyroptosis can activate an immune response for resistance against cancer. Consequently, elevated levels of cytokines released by cancer cells are highly correlated with the effectiveness of… read more here.
Keywords: cancer; noninvasive sers; cell pyroptosis; sers immunosensors ... See more keywords
MiR-192 attenuates high glucose-induced pyroptosis in retinal pigment epithelial cells via inflammasome modulation.
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2044734
Abstract: Diabetic retinopathy is one of the most characteristic complications of diabetes mellitus, and pyroptosis plays acrucial role in the onset and development of diabetic retinopathy. Although microRNA-192 (miR-192) has been demonstrated to be involved in… read more here.
Keywords: mir 192; cell pyroptosis; pyroptosis retinal; pyroptosis ... See more keywords
A3067 Eplerenone inhibits the cell pyroptosis in contralateral kidney of UUO rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000548095.91094.dd
Abstract: Objectives: To investigate the inhibitory effect of eplerenone, an aldosterone receptor blocker, on cell pyroptosis in contralateral kidney of UUO rats, and to elucidate the role of aldosterone in the process of unilateral renal injury-induced… read more here.
Keywords: uuo rats; contralateral kidney; eplerenone; kidney uuo ... See more keywords
Melatonin prevents endothelial cell pyroptosis via regulation of long noncoding RNA MEG3/miR‐223/NLRP3 axis
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DOI: 10.1111/jpi.12449
Abstract: Atherosclerosis (AS) is an inflammatory disease linked to endothelial dysfunction. Melatonin is reported to possess substantial anti‐inflammatory properties, which has proven to be effective in AS. Emerging literature suggests that pyroptosis plays a critical role… read more here.
Keywords: meg3; pyroptosis; endothelial cell; mir 223 ... See more keywords
Pectic polysaccharides derived from Hainan Rauwolfia ameliorates NLRP3-mediated colonic epithelial cell pyroptosis in ulcerative colitis.
Sign Up to like & getrecommendations! Published in 2022 at "Physiological genomics"
DOI: 10.1152/physiolgenomics.00081.2022
Abstract: Pectic polysaccharides (PP) could exert functions on ulcerative colitis (UC), which is classified as a non-specific inflammatory disorder. This study investigated the molecular mechanism of PP derived from Rauwolfia in UC. Firstly, the dextran sodium… read more here.
Keywords: colonic epithelial; pyroptosis; cell pyroptosis; epithelial cell ... See more keywords