Amniotic MSCs reduce pulmonary fibrosis by hampering lung B‐cell recruitment, retention, and maturation
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.20-0068
Abstract: Abstract Growing evidence suggests a mechanistic link between inflammation and the development and progression of fibrotic processes. Mesenchymal stromal cells derived from the human amniotic membrane (hAMSCs), which display marked immunomodulatory properties, have been shown… read more here.
Keywords: cell recruitment; fibrosis; lung; hamscs ... See more keywords
CCL18 – Beyond chemotaxis
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.01.023
Abstract: HighlightsCCL18 is constitutively expressed and up‐regulated in diseases.CCL18 has a weak chemotactic activity toward multiple immune cells including Treg.CCL18 inhibits chemokine‐related cell recruitment by binding to glycosaminoglycans.CCL18 gives immune cells a regulatory phenotype and function… read more here.
Keywords: beyond chemotaxis; cell recruitment; ccl18 beyond; ccl18 ... See more keywords
Dendritic cell recruitment and activation in autoimmunity.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2017.07.012
Abstract: Dendritic cells (DCs) are professional antigen presenting cells displaying the unique capability to activate naïve T cells. DCs react to pathogen encounter also by the production of mediators of inflammation, including pro-inflammatory cytokines. Because of… read more here.
Keywords: cell recruitment; tissue; autoimmunity; activation ... See more keywords
ACELLULAR LIVER SCAFFOLD PROMOTES CELL RECRUITMENT AFTER HETEROTOPIC TRANSPLANTATION
Sign Up to like & getrecommendations! Published in 2021 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2021.02.010
Abstract: Background Liver tissue engineering is a promising tool to solve the shortage of organs. In this context, acellular liver scaffolds (ALS) obtained by decellularization are an attractive substrate to organ transplantation. However, the cell recruitment… read more here.
Keywords: acellular liver; cell recruitment; liver; transplantation ... See more keywords
HTLV-1-induced leukotriene B4 secretion by T cells promotes T cell recruitment and virus propagation
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15890
Abstract: The human T-lymphotropic virus type 1 (HTLV-1) is efficiently transmitted through cellular contacts. While the molecular mechanisms of viral cell-to-cell propagation have been extensively studied in vitro, those facilitating the encounter between infected and target… read more here.
Keywords: htlv; cell recruitment; virus propagation; secretion ... See more keywords
Deregulated immune cell recruitment orchestrated by FOXM1 impairs human diabetic wound healing
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-18276-0
Abstract: Diabetic foot ulcers (DFUs) are a life-threatening disease that often result in lower limb amputations and a shortened lifespan. However, molecular mechanisms contributing to the pathogenesis of DFUs remain poorly understood. We use next-generation sequencing… read more here.
Keywords: wound healing; immune cell; cell recruitment; recruitment orchestrated ... See more keywords
B Cell Recruitment Follows Kidney Injury and Maladaptive Repair.
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation"
DOI: 10.1097/tp.0000000000002723
Abstract: only during embronic development (eg, carcinoembryonic antigen). The fetus is not completely physically isolated from the maternal immune system, and there is evidence for the development of an adaptive immune response during pregnancy. In fact,… read more here.
Keywords: development; treg; cell recruitment; pregnancy ... See more keywords
Bruton's tyrosine kinase (BTK) regulates myeloid cell recruitment during acute inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of pharmacology"
DOI: 10.1111/bph.15778
Abstract: BACKGROUND AND PURPOSE Bruton's tyrosine kinase (BTK) is a non-receptor kinase best known for its role in B lymphocyte development that is critical for proliferation, and survival of leukemic cells in B cell malignancies. However,… read more here.
Keywords: recruitment; kinase; cell recruitment; myeloid cell ... See more keywords
PTPN2 elicits cell autonomous and non–cell autonomous effects on antitumor immunity in triple-negative breast cancer
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abk3338
Abstract: The tumor-suppressor PTPN2 is diminished in a subset of triple-negative breast cancers (TNBCs). Paradoxically, PTPN2-deficiency in tumors or T cells in mice can facilitate T cell recruitment and/or activation to promote antitumor immunity. Here, we… read more here.
Keywords: cell; cell autonomous; triple negative; ptpn2 ... See more keywords
Abstract LB-B11: Myeloid p38 MAPK promotes tumorigenesis by suppressing cytotoxic T cell recruitment
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.targ-19-lb-b11
Abstract: The last decade has seen explosive progress in understanding how tumor-associated macrophages (TAM) contribute to the development, metastasis, and therapy resistance of cancer. TAM and their molecular components are investigated as targets for cancer therapy.… read more here.
Keywords: expression; p38; cancer; cell recruitment ... See more keywords
PARP-1 controls NK cell recruitment to the site of viral infection.
Sign Up to like & getrecommendations! Published in 2019 at "JCI insight"
DOI: 10.1172/jci.insight.121291
Abstract: The activation and recruitment of NK cells to the site of viral infection are crucial for virus control. However, it remains largely unknown what controls the recruitment of the activated NK cells to the infection… read more here.
Keywords: cell recruitment; infection; site; viral infection ... See more keywords