Beta cell regeneration upon magainin and growth hormone treatment as a possible alternative to insulin therapy
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13556
Abstract: Insulin therapy, pancreas transplantation and β cell regeneration are among the suggested treatment strategies for type 1 diabetes. It has been shown that some antimicrobial peptides have the potential to increase insulin release and to… read more here.
Keywords: cell; insulin therapy; cell regeneration; treatment ... See more keywords
Phenylephrine alleviates 131I damage in submandibular gland through promoting endogenous stem cell regeneration via lissencephaly-1 upregulation.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2020.114999
Abstract: Thyroid cancer is the most common endocrine malignancy. 131I ablation therapy is an effective treatment for patients with differentiated thyroid cancer (DTC) but frequently causes radiation damage in salivary glands (SGs). Stem cell-based regenerative therapy… read more here.
Keywords: cell regeneration; endogenous stem; stem cell; lis1 ... See more keywords
Regenerating β cells of the pancreas – potential developments in diabetes treatment
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2018.1402885
Abstract: ABSTRACT Introduction: The etiology of diabetes is mainly attributed to insulin deficiency due to the lack of β cells (type 1), or to insulin resistance that eventually results in β cell dysfunction (type 2). Therefore,… read more here.
Keywords: insulin; cell regeneration; treatment; cell ... See more keywords
Direct cellular reprogramming and inner ear regeneration
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2019.1564035
Abstract: ABSTRACT Introduction: Sound is integral to communication and connects us to the world through speech and music. Cochlear hair cells are essential for converting sounds into neural impulses. However, these cells are highly susceptible to… read more here.
Keywords: cell regeneration; hair cell; hair; regeneration ... See more keywords
Rps14 upregulation promotes inner ear progenitor proliferation and hair cell regeneration in the neonatal mouse cochlea
Sign Up to like & getrecommendations! Published in 2023 at "Cell Proliferation"
DOI: 10.1111/cpr.13458
Abstract: Sensorineural hearing loss a result from hair cell damage, which is irreversible in mammals owing to the lack of hair cell regeneration, but recent researches have shown that Lgr5+ supporting cells are progenitors capable of… read more here.
Keywords: cell; hair cell; rps14; hair ... See more keywords
Application of Novel Drugs for Corneal Cell Regeneration
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Ophthalmology"
DOI: 10.1155/2018/1215868
Abstract: Corneal transplantation has been the only treatment method for corneal blindness, which is the major cause of reversible blindness. However, despite the advancement of surgical techniques for corneal transplantation, demand for the surgery can never… read more here.
Keywords: novel drugs; corneal cell; application novel; cell regeneration ... See more keywords
microRNA-183 is Essential for Hair Cell Regeneration after Neomycin Injury in Zebrafish
Sign Up to like & getrecommendations! Published in 2018 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2018.59.1.141
Abstract: Purpose microRNAs (miRNAs) are non-coding RNAs composed of 20 to 22 nucleotides that regulate development and differentiation in various organs by silencing specific RNAs and regulating gene expression. In the present study, we show that… read more here.
Keywords: cell regeneration; hair cell; mir 183; hair ... See more keywords
Phenotype-based drug screening: An in vivo strategy to classify and identify the chemical compounds modulating zebrafish M-cell regeneration
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.984461
Abstract: Several disease-modulatory FDA-approved drugs are being used in patients with neurodegenerative diseases. However, information on their toxicity-related profiles is very limited. Therefore, measurement of drug toxicity is essential to increase the knowledge of their side… read more here.
Keywords: phenotype based; regeneration; cell regeneration; based drug ... See more keywords
Approaches to Inducing β-Cell Regeneration
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10030571
Abstract: β-cell number and/or function is reduced in diabetes. Thus, inducing the formation of new β-cells has been a major goal of diabetes research. However, the pathway(s) by which new β-cells form when preexisting β-cells are… read more here.
Keywords: cell; preexisting cells; approaches inducing; cell regeneration ... See more keywords
Recombinant Reg3α Prevents Islet β-Cell Apoptosis and Promotes β-Cell Regeneration
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810584
Abstract: Progressive loss and dysfunction of islet β-cells has not yet been solved in the treatment of diabetes. Regenerating protein (Reg) has been identified as a trophic factor which is demonstrated to be associated with pancreatic… read more here.
Keywords: regeneration; cell; promotes cell; rreg3 ... See more keywords
β cell regeneration and novel strategies for treatment of diabetes (Review).
Sign Up to like & getrecommendations! Published in 2022 at "Biomedical reports"
DOI: 10.3892/br.2022.1555
Abstract: The etiology of diabetes is primarily attributed to the lack of functioning β cells, which in-turn leads to insulin deficiency or insulin resistance, and this ultimately leads to β cell dysfunction. Restoring the number and… read more here.
Keywords: cell; treatment diabetes; cell regeneration; strategies treatment ... See more keywords