Macrophages release neuraminidase and cleaved calreticulin for programmed cell removal
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2426644122
Abstract: Significance This study provides insights into the mechanisms by which macrophages mark target cells for programmed cell removal (PrCR). We demonstrate that activated macrophages secrete a C-terminally cleaved version of Calreticulin (CALR), which acts as… read more here.
Keywords: cell removal; programmed cell; cell; macrophages release ... See more keywords
Innate immunity mediated longevity and longevity induced by germ cell removal converge on the C-type lectin domain protein IRG-7
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DOI: 10.1371/journal.pgen.1006577
Abstract: In C. elegans, removal of the germline triggers molecular events in the neighboring intestine, which sends an anti-aging signal to the rest of the animal. In this study, we identified an innate immunity related gene,… read more here.
Keywords: cell removal; innate immunity; longevity; germ cell ... See more keywords
Robotic Manipulation of Cumulus–Oocyte Complexes for Cumulus Cell Removal
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DOI: 10.3390/app14188450
Abstract: The removal of cumulus cells from cumulus–oocyte complexes is a critical step in clinical in vitro fertilization. Since the oocyte is partially occluded by the surrounding cumulus cells and individual cumulus cells are small in… read more here.
Keywords: cumulus cell; oocyte complexes; cell removal; cumulus oocyte ... See more keywords