Immunological Issues After Stem Cell-Based β Cell Replacement
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DOI: 10.1007/s11892-017-0901-4
Abstract: Purpose of ReviewIslet and pancreas transplantation prove that β cell replacement can cure the glycemic derangements in type 1 diabetes (T1D). Induced pluripotent stem cells (iPSCs) can differentiate into functional insulin-producing cells, able to restore… read more here.
Keywords: cell replacement; stem cell; immunological issues; issues stem ... See more keywords
Induced pluripotent stem cells derived from the developing striatum as a potential donor source for cell replacement therapy for Huntington disease
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DOI: 10.1016/j.jcyt.2020.06.001
Abstract: Background Cell replacement therapy (CRT) for Huntington disease (HD) requires a source of striatal (STR) progenitors capable of restoring the function lost due to STR degeneration. Authentic STR progenitors can be collected from the fetal… read more here.
Keywords: cell replacement; source; str; donor ... See more keywords
&bgr; Cell Replacement Therapy: The Next 10 Years
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DOI: 10.1097/tp.0000000000001937
Abstract: Abstract &bgr; cell replacement with either pancreas or islet transplantation has progressed immensely over the last decades with current 1- and 5-year insulin independence rates of approximately 85% and 50%, respectively. Recent advances are largely… read more here.
Keywords: bgr cell; cell replacement; pancreas islet;
Advances in insulin therapy from discovery to β‐cell replacement
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DOI: 10.1111/jdi.13902
Abstract: Insulin therapy using insulin purified from porcine or bovine pancreas revolutionized diabetes therapy in the 1920s. A series of advances including cloning human insulin cDNA enabled the development of recombinant human insulin with improved features.… read more here.
Keywords: advances insulin; insulin therapy; cell replacement;
Endogenous versus exogenous cell replacement for Parkinson’s disease: where are we at and where are we going?
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.336137
Abstract: Parkinson’s disease is the second most common neurodegenerative disease and has currently no effective treatment, one that would be able to stop or reverse the loss of dopaminergic neurons in the substantia nigra pars compacta.… read more here.
Keywords: disease; parkinson disease; cell replacement;