Comparison of efficacy between HLA6/6- and HLA3/6-matched haploidentical hematopoietic stem cell transplant in T-cell-replete transplants between parents and children
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DOI: 10.1007/s11427-017-9302-1
Abstract: To compare the efficacy of HLA6/6-matched haploidentical hematopoietic stem cell transplant (haplo-HSCT) with that of HLA3/6-matched HSCT in T-cell-replete transplants, we recruited 27 consecutive recipients from multiple centers who received HLA6/6-matched haplo-HSCT from a parent… read more here.
Keywords: cell replete; hla6 hla3; hla6; hla3 matched ... See more keywords
Irradiation‐free, T‐cell replete haploidentical transplant for Fanconi anaemia, weighing the benefits
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DOI: 10.1111/bjh.18446
Abstract: The optimal haploidentical haematopoietic cell transplant approach for Fanconi anaemia (FA) patients is not well established, given the rarity of the disease, the increased sensitivity to DNA‐damaging agents and the high risk of severe graft‐versus‐host… read more here.
Keywords: irradiation; cell; fanconi anaemia; replete haploidentical ... See more keywords
Impact of cyclosporine‐A concentration in T‐cell replete haploidentical allogeneic stem cell transplantation
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DOI: 10.1111/ctr.13220
Abstract: This paper aims to study whether cyclosporine‐A (CSA) levels have an impact on the clinical outcome of patients with T‐cell replete haploidentical allogeneic hematopoietic stem cell transplantation (allo‐HSCT). We analyzed 140 consecutive patients who had… read more here.
Keywords: allo hsct; cell replete; replete haploidentical; concentration ... See more keywords
Cytokine Release Syndrome after Peripheral Blood T-Cell Replete Haploidentical Transplantation Is Not Prevented By Dexamethasone and Limits Its Full-Outpatient Conduction
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DOI: 10.1182/blood-2018-99-116996
Abstract: Introduction: Our center has implemented an outpatient-based peripheral blood haploidentical HSCT (haplo-HSCT) program since 2012. Cytokine release syndrome (CRS) associated with T-cell replete haplo-HSCT is characterized by fever and high levels of inflammatory cytokines with… read more here.
Keywords: day; haplo hsct; crs; cell replete ... See more keywords
Myeloablative vs reduced intensity T-cell-replete haploidentical transplantation for hematologic malignancy.
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DOI: 10.1182/bloodadvances.2019000627
Abstract: In the absence of prospective studies that examine the effect of conditioning regimen intensity after T-cell-replete haploidentical transplant for acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and myelodysplastic syndrome (MDS), a retrospective cohort analysis… read more here.
Keywords: cell replete; replete haploidentical; intensity; regimen intensity ... See more keywords
T-Cell Replete Myeloablative Haploidentical Bone Marrow Transplantation Is an Effective Option for Pediatric and Young Adult Patients With High-Risk Hematologic Malignancies
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DOI: 10.3389/fped.2020.00282
Abstract: Twenty-one pediatric and young adult patients (1.1–24.7 years) with hematologic malignancies underwent myeloablative T-cell replete haploidentical bone marrow transplant (haplo-BMT) between October 2015 to December 2019. Fifty-seven percent of the patients were ethnic or racial… read more here.
Keywords: young adult; pediatric young; cell replete; hematologic malignancies ... See more keywords