Omicron-Specific Cytotoxic T-Cell Responses After a Third Dose of mRNA COVID-19 Vaccine Among Patients With Multiple Sclerosis Treated With Ocrelizumab.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.0245
Abstract: Importance The SARS-CoV-2 variant B.1.1.529 (Omicron) escapes neutralizing antibodies elicited after COVID-19 vaccination, while T-cell responses might be better conserved. It is crucial to assess how a third vaccination modifies these responses, particularly for immunocompromised… read more here.
Keywords: cell; cell responses; omicron; vaccination ... See more keywords
Systemic interferon type I and B cell responses are impaired in autoimmune polyendocrine syndrome type 1
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14625
Abstract: Autoimmune polyendocrine syndrome type I (APS‐1) is caused by mutations in the autoimmune regulator (AIRE) gene and characterised clinically by multiple autoimmune manifestations and serologically by autoantibodies against tissue proteins and cytokines. We here hypothesised… read more here.
Keywords: syndrome type; cell; autoimmune polyendocrine; polyendocrine syndrome ... See more keywords
Turning the Old Adjuvant from Gel to Nanoparticles to Amplify CD8+ T Cell Responses
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Science"
DOI: 10.1002/advs.201700426
Abstract: Abstract Due to its safety and efficacy, aluminum hydroxide is used as an immune adjuvant in human vaccines for over 80 years. Being a Th2 stimulator, the classical gel‐like adjuvant, however, fails to generate CD8+… read more here.
Keywords: cd8 cell; cell responses; turning old; gel ... See more keywords
Position-Scanning Peptide Libraries as Particle Immunogens for Improving CD8+ T-Cell Responses.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced science"
DOI: 10.1002/advs.202103023
Abstract: Short peptides reflecting major histocompatibility complex (MHC) class I (MHC-I) epitopes frequently lack sufficient immunogenicity to induce robust antigen (Ag)-specific CD8+ T cell responses. In the current work, it is demonstrated that position-scanning peptide libraries… read more here.
Keywords: cd8 cell; cell responses; cd8; position scanning ... See more keywords
Characterization of B Cell Responses in Rainbow Trout (Oncorhynchus Mykiss) Affected by Red Mark Syndrome
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202503047
Abstract: Red mark syndrome (RMS) is a disease affecting rainbow trout. Although the precise etiology of this disease is still under debate, a Midichloria‐like organism (MLO) is suspected as the triggering agent. RMS provokes characteristic skin… read more here.
Keywords: red mark; rainbow trout; mark syndrome; cell ... See more keywords
Fluorescent Cell Barcoding of Peripheral Blood Mononuclear Cells for High‐Throughput Assessment of Vaccine‐Induced T Cell Responses in Low‐Volume Research Samples
Sign Up to like & getrecommendations! Published in 2025 at "Cytometry Part A"
DOI: 10.1002/cyto.a.24933
Abstract: T cell responses are rarely measured in large‐scale human vaccine studies due to the sample volumes required, as well as the logistical, technical, and financial challenges associated with available assays. Fluorescent cell barcoding has been… read more here.
Keywords: high throughput; fluorescent cell; cell; vaccine ... See more keywords
Monocytic myeloid‐derived suppressor cells regulate T‐cell responses against vaccinia virus
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Immunology"
DOI: 10.1002/eji.201646797
Abstract: Vaccinia virus (VV) can potently activate NK‐ and T‐cell responses, leading to efficient viral control and generation of long‐lasting protective immunity. However, immune responses against viral infections are often tightly controlled to avoid collateral damage… read more here.
Keywords: myeloid derived; cell responses; infection; mdscs ... See more keywords
Dysregulation in B‐cell responses and T follicular helper cell function in ADA2 deficiency patients
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Immunology"
DOI: 10.1002/eji.202048549
Abstract: Adenosine deaminase 2 deficiency (DADA2) is an autoinflammatory disease characterized by inflammatory vasculopathy, early strokes associated often with hypogammaglobulinemia. Pure red cell aplasia, thrombocytopenia, and neutropenia have been reported. The defect is due to biallelic… read more here.
Keywords: cell responses; cell; cell function; function ada2 ... See more keywords
Distinct HLA Haplotypes Are Associated With an Altered Strength of SARS‐CoV‐2‐Specific T‐Cell Responses and Unfavorable Disease Courses
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Immunology"
DOI: 10.1002/eji.202451497
Abstract: Infection with SARS‐CoV‐2 results in mild to severe COVID‐19 disease courses. Several studies showed the association of impaired T‐cell responses and certain HLA haplotypes with disease severity. However, it remained unclear if T‐cell activation was… read more here.
Keywords: sars cov; disease courses; cell; cell responses ... See more keywords
Human T Cell Responses to Flavivirus Vaccines
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Immunology"
DOI: 10.1002/eji.70027
Abstract: Flaviviruses are major human pathogens that continue to pose a global health threat, and vaccination is an effective strategy to protect against disease from several flaviviruses. Flavivirus vaccines are believed to confer protection primarily through… read more here.
Keywords: immunity; flavivirus vaccines; human cell; responses flavivirus ... See more keywords
Human vascular cell responses to the circulating bone hormone osteocalcin
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28707
Abstract: The purpose of this study was to characterize the direct effects of uncarboxylated osteocalcin (ucOCN) on vascular cell biology in vitro, to assess its potential function in pathophysiological conditions such as atherosclerosis. Human aortic endothelial… read more here.
Keywords: cell responses; human vascular; vascular cell; cell ... See more keywords