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   Articles with "cell rna" as a keyword



Current trends in single‐cell RNA sequencing applications in diabetes mellitus

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recommendations! Published in 2025 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.70061

Abstract: Diabetes mellitus (DM) is among the most prevalent metabolic diseases worldwide, associated with an increased risk of mortality. Although numerous studies have been conducted to uncover the cellular and molecular pathways associated with DM pathogenesis,… read more here.

Keywords: diabetes mellitus; cell rna; rna sequencing; single cell ... See more keywords

Single-Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage.

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recommendations! Published in 2025 at "Advanced science"

DOI: 10.1002/advs.202500438

Abstract: Epidemiological and clinical observations suggest a substantial reduction in the risk and severity of diabetic retinopathy (DR) among individuals with myopia. However, the impact of myopia on DR and its underlying mechanisms remains unclear. Herein,… read more here.

Keywords: single cell; myopia; cell rna; diabetic retinopathy ... See more keywords

FemXpress: Systematic Analysis of X Chromosome Inactivation Heterogeneity in Female Single‐Cell RNA‐Seq Samples

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recommendations! Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202504754

Abstract: X chromosome inactivation (XCI) is crucial for balancing X‐linked gene dosage in female cells by randomly silencing one X chromosome during early embryogenesis. However, accurately classifying cells based on the parental origin of the inactivated… read more here.

Keywords: single cell; cell; seq; chromosome ... See more keywords

Single-Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease.

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recommendations! Published in 2025 at "Advanced science"

DOI: 10.1002/advs.202508449

Abstract: Graves' disease (GD) is an autoimmune disorder primarily targeting the thyroid tissue. While major histocompatibility complex (MHC)‐dependent B cell activation and thyroid‐stimulating hormone receptor (TSHR) autoantibody production are central to GD, the intrathyroidal immune landscape… read more here.

Keywords: single cell; graves disease; rna sequencing; cell ... See more keywords
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Creating Lineage Trajectory Maps Via Integration of Single‐Cell RNA‐Sequencing and Lineage Tracing

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recommendations! Published in 2018 at "BioEssays"

DOI: 10.1002/bies.201800056

Abstract: Mapping the paths that stem and progenitor cells take en route to differentiate and elucidating the underlying molecular controls are key goals in developmental and stem cell biology. However, with population level analyses it is… read more here.

Keywords: single cell; lineage trajectory; lineage; cell rna ... See more keywords

Single cell RNA‐sequencing: A powerful yet still challenging technology to study cellular heterogeneity

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recommendations! Published in 2022 at "BioEssays"

DOI: 10.1002/bies.202200084

Abstract: Almost all biomedical research to date has relied upon mean measurements from cell populations, however it is well established that what it is observed at this macroscopic level can be the result of many interactions… read more here.

Keywords: cell; heterogeneity; rna sequencing; single cell ... See more keywords
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Role of stemness-related genes TIMP1, PGF, and SNAI1 in the prognosis of colorectal cancer through single-cell RNA-seq.

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recommendations! Published in 2023 at "Cancer medicine"

DOI: 10.1002/cam4.5833

Abstract: Colorectal cancer (CRC) is a fatal malignant tumor with poor prognosis. Cancer stem cells (CSCs) can cause metastasis, recurrence and drug resistance in CRC. This research aimed to analyze stemness‐related prognostic genes of CRC based… read more here.

Keywords: prognosis; single cell; colorectal cancer; cell rna ... See more keywords

Large-scale single cell RNA sequencing atlases of human immune cells across lifespan: possibilities and challenges.

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recommendations! Published in 2023 at "European journal of immunology"

DOI: 10.1002/eji.202250222

Abstract: Single cell RNA sequencing technologies have been successfully leveraged for immunological insights into human prenatal, paediatric and adult tissues. These single cell studies have led to breakthroughs in our understanding of stem, myeloid and lymphoid… read more here.

Keywords: cell; rna sequencing; large scale; single cell ... See more keywords

In silico analysis of single‐cell RNA sequencing data from 3 and 7 days old mouse spermatogonial stem cells to identify their differentially expressed genes and transcriptional regulators

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recommendations! Published in 2018 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.27066

Abstract: Spermatogonial stem cells (SSCs), which are at the basis of spermatogenesis process, are valuable cells with different applications in biotechnology and regenerative medicine. Understanding the molecular basis of SSC self‐renewal and differentiation at various developmental… read more here.

Keywords: days old; single cell; spermatogonial stem; cell rna ... See more keywords

Single‐cell RNA analysis of chromodomain‐encoding genes in mesenchymal stromal cells of the mouse dental pulp

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recommendations! Published in 2024 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.30608

Abstract: The chromodomain helicase DNA‐binding (CHD) and chromobox (CBX) families of proteins play crucial roles in cell fate decisions, differentiation, and cell proliferation in a broad variety of tissues and cell types. CHD proteins are ATP‐dependent… read more here.

Keywords: chd cbx; single cell; encoding genes; cell ... See more keywords

Single‐cell RNA‐sequencing of retrieved human oocytes and eggs in clinical practice and for human ovarian cell atlasing

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recommendations! Published in 2022 at "Molecular Reproduction and Development"

DOI: 10.1002/mrd.23648

Abstract: With the advancement of single‐cell separation techniques and high‐throughput sequencing platforms, single‐cell RNA‐sequencing (scRNA‐seq) has emerged as a vital technology for understanding tissue and organ systems at cellular resolution. Through transcriptional analysis, it is possible… read more here.

Keywords: cell; rna sequencing; scrna seq; single cell ... See more keywords