Fluidization-mediated tissue spreading by mitotic cell rounding and non-canonical Wnt signalling
Sign Up to like & getrecommendations! Published in 2018 at "Nature Cell Biology"
DOI: 10.1038/s41556-018-0247-4
Abstract: Tissue morphogenesis is driven by mechanical forces that elicit changes in cell size, shape and motion. The extent by which forces deform tissues critically depends on the rheological properties of the recipient tissue. Yet, whether… read more here.
Keywords: mitotic cell; tissue; non canonical; cell rounding ... See more keywords
CDK1-cyclin-B1-induced kindlin degradation drives focal adhesion disassembly at mitotic entry.
Sign Up to like & getrecommendations! Published in 2022 at "Nature cell biology"
DOI: 10.1038/s41556-022-00886-z
Abstract: The disassembly of integrin-containing focal adhesions (FAs) at mitotic entry is essential for cell rounding, mitotic retraction fibre formation, bipolar spindle positioning and chromosome segregation. The mechanism that drives FA disassembly at mitotic entry is… read more here.
Keywords: entry; kindlin degradation; disassembly mitotic; mitotic entry ... See more keywords
Preprint Highlight: Interphase microtubule disassembly is a signaling cue that drives cell rounding at mitotic entry.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology of the cell"
DOI: 10.1091/mbc.p22-03-1005
Abstract: Metaphase cell rounding is an important step during cell division; however, the cell cycle regulation of the ezrin, radixin, and moesin (ERM) proteins which drive cell rounding is not well understood. Using a small molecule… read more here.
Keywords: cell rounding; erm proteins; microtubule disassembly; microtubule ... See more keywords
Rnd3 interacts with TAO kinases and contributes to mitotic cell rounding and spindle positioning
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.235895
Abstract: ABSTRACT Rnd3 is an atypical Rho family protein that is constitutively GTP bound, and acts on membranes to induce loss of actin stress fibers and cell rounding. Phosphorylation of Rnd3 promotes 14-3-3 binding and its… read more here.
Keywords: mitotic cell; rounding spindle; spindle positioning; cell rounding ... See more keywords