Single cell sequencing of the mouse anterior palate reveals mesenchymal heterogeneity
Sign Up to like & getrecommendations! Published in 2023 at "Developmental Dynamics"
DOI: 10.1002/dvdy.573
Abstract: Cleft palate is one of the most prevalent birth defects. Mice are useful for studying palate development because of their morphological and genetic similarities to humans. In mice, palate development occurs between embryonic days (E)11.5… read more here.
Keywords: palate; cell sequencing; single cell; anterior palate ... See more keywords
Immune landscape of viral cancers: Insights from single‐cell sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28348
Abstract: Viral infections trigger a wide range of immune responses thought to drive tumorigenesis and malignant progression. Dissecting virus‐induced changes in the tumor immune microenvironment (TIME) is therefore crucial to identify key leukocyte populations that may… read more here.
Keywords: cell; cell sequencing; single cell; immune landscape ... See more keywords
Single-Cell Sequencing in Precision Medicine.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer treatment and research"
DOI: 10.1007/978-3-030-16391-4_9
Abstract: The application of next-generation sequencing in cancer genomics allowed for a better understanding of the genetics and pathogenesis of cancer. Single-cell genomics is a relatively new field that has enhanced our current knowledge of the… read more here.
Keywords: single cell; medicine; cell sequencing; cancer ... See more keywords
An Informative Approach to Single-Cell Sequencing Analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-6037-4_6
Abstract: Recent advances in sequencing technologies enable us to obtain genome, epigenome and transcriptome data in individual cells. In this review, we describe various platforms for single-cell sequencing analysis across multiple layers. We mainly introduce an… read more here.
Keywords: single cell; cell rna; rna seq; cell sequencing ... See more keywords
Understanding Diseases from Single-Cell Sequencing and Methylation.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-4494-1_1
Abstract: Clinical single-cell biomedicine has become a new emerging discipline, which integrates single-cell RNA and DNA sequencing, proteomics, and functions with clinical phenomes, therapeutic responses, and prognosis. It is of great value to discover disease-, phenome-,… read more here.
Keywords: single cell; understanding diseases; cell sequencing; sequencing methylation ... See more keywords
Single-Cell Sequencing in Genitourinary Malignancies.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-4494-1_13
Abstract: Single-cell sequencing (SCS) is a powerful new tool that applies Next Generation Sequencing at the cellular level. SCS has revolutionized our understanding of tumor heterogeneity and the tumor microenvironment, immune infiltration, cancer stem cells (CSCs),… read more here.
Keywords: single cell; genitourinary malignancies; heterogeneity; cell sequencing ... See more keywords
Single cell sequencing revealed the underlying pathogenesis of the development of osteoarthritis.
Sign Up to like & getrecommendations! Published in 2020 at "Gene"
DOI: 10.1016/j.gene.2020.144939
Abstract: Osteoarthritis (OA) is a chronic degenerative change with high incidence and leads to a lower quality of life and a larger socioeconomic burden. This study aimed to explore potential crucial genes and pathways associated with… read more here.
Keywords: single cell; osteoarthritis; sequencing revealed; cell sequencing ... See more keywords
Single-cell sequencing paints diverse pictures of the brain
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/d41586-018-07027-3
Abstract: A single-cell sequencing study reveals how different types of neuron are distributed in the brain. An analysis then demonstrates how these data can improve our understanding of neuronal functions.In-depth transcriptomic analysis of the mouse cortex. read more here.
Keywords: single cell; paints diverse; sequencing paints; cell sequencing ... See more keywords
Whole-organism clone tracing using single-cell sequencing
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/nature25969
Abstract: Embryonic development is a crucial period in the life of a multicellular organism, during which limited sets of embryonic progenitors produce all cells in the adult body. Determining which fate these progenitors acquire in adult… read more here.
Keywords: single cell; clonal history; organism; cell sequencing ... See more keywords
BFF and cellhashR: analysis tools for accurate demultiplexing of cell hashing data
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac213
Abstract: MOTIVATION Single-cell sequencing methods provide previously impossible resolution into the transcriptome of individual cells. Cell hashing reduces single-cell sequencing costs by increasing capacity on droplet-based platforms. Cell hashing methods rely on demultiplexing algorithms to accurately… read more here.
Keywords: cell; cellhashr; cell sequencing; single cell ... See more keywords
Single-pollen-cell sequencing for gamete-based phased diploid genome assembly in plants
Sign Up to like & getrecommendations! Published in 2019 at "Genome Research"
DOI: 10.1101/gr.251033.119
Abstract: Genome assemblies from diploid organisms create mosaic sequences alternating between parental alleles, which can create erroneous gene models and other problems. In animals, a popular strategy to generate haploid genome-resolved assemblies has been the sampling… read more here.
Keywords: cell sequencing; haploid; genome; pollen ... See more keywords