Reliable Harvest of Injectable Human Mesenchymal Stem Cell Sheets by Modulating Cell‐Substrate Adhesion Strength
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202500135
Abstract: Cell sheet engineering has emerged as a promising scaffold‐free strategy in cell‐based therapeutics, preserving essential cell‐cell and cell‐extracellular matrix (ECM) interactions. To enable minimally invasive delivery, a key challenge relies on making the cell sheets… read more here.
Keywords: human mesenchymal; cell sheet; mesenchymal stem; adhesion ... See more keywords
Transfer‐Tattoo‐Like Cell‐Sheet Delivery Induced by Interfacial Cell Migration
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202204390
Abstract: A direct transfer of a cell sheet from a culture surface to a target tissue is introduced. Commercially available, flexible parylene is used as the culture surface, and it is proposed that the UV‐treated parylene… read more here.
Keywords: cell; transfer; interfacial cell; cell sheet ... See more keywords
Surface coatings of contact lenses for cell sheet transplantation
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.55458
Abstract: The field of corneal cell sheet engineering has evolved rapidly in the last decade; however, challenges related to transplantation into target tissue still exist, necessitating a new approach to integrate cell sheet technology onto a… read more here.
Keywords: cell sheet; contact lenses; surface; cell ... See more keywords
Application of cell sheet technology to bone marrow stromal cell transplantation for rat brain infarct
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.1920
Abstract: Bone marrow stromal cells (BMSC) transplantation enhances functional recovery after cerebral infarct, but the optimal delivery route is undetermined. This study was aimed to assess whether a novel cell‐sheet technology non‐invasively serves therapeutic benefits to… read more here.
Keywords: sheet technology; sheet; transplantation; cell sheet ... See more keywords
Cell sheet-based multilayered liver tumor models for anti-cancer drug screening
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology Letters"
DOI: 10.1007/s10529-017-2476-1
Abstract: ObjectiveTo fabricate in vitro cell-dense, three-dimensional (3D) tumor models by employing a cell sheet technology for testing anti-cancer drug efficacy.ResultsThe stratified liver tumor models were fabricated by stacking contiguous HepG2 cell sheets. Triple-layer (3L), double-layer… read more here.
Keywords: cell sheet; cell; liver tumor; tumor models ... See more keywords
Development and characterization of hybrid tubular structure of PLCL porous scaffold with hMSCs/ECs cell sheet
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Materials Science: Materials in Medicine"
DOI: 10.1007/s10856-017-5985-5
Abstract: Tissue engineering offers an alternate approach to providing vascular graft with potential to grow similar with native tissue by seeding autologous cells into biodegradable scaffold. In this study, we developed a combining technique by layering… read more here.
Keywords: scaffold; sheet; structure; cell sheet ... See more keywords
Cell sheet biofabrication by co-administration of mesenchymal stem cells secretome and vitamin C on thermoresponsive polymer
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Materials Science: Materials in Medicine"
DOI: 10.1007/s10856-018-6180-z
Abstract: AbstractCell sheet technology aims at replacement of artificial extracellular matrix (ECM) or scaffolds, popular in tissue engineering, with natural cell derived ECM. Adipose tissue mesenchymal stem cells (ASCs) have the ability of ECM secretion and… read more here.
Keywords: stem cells; sheet; cell sheet; cell ... See more keywords
Graphene Oxide Nanosheet-Composited Poly(N-isopropylacrylamide) Hydrogel for Cell Sheet Recovery
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular Research"
DOI: 10.1007/s13233-019-7099-z
Abstract: AbstractCell sheet engineering technique has been applied to treat various tissues without the use of a traditional scaffold. To date, methods for the cell sheet harvesting depend mostly on grafted poly(N-isopropylacrylamide) (pNIPAAm) thin layers, while… read more here.
Keywords: cell sheet; cell; pnipaam hydrogel; hydrogel ... See more keywords
Cell sheet engineering using the stromal vascular fraction of adipose tissue as a vascularization strategy.
Sign Up to like & getrecommendations! Published in 2017 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2017.03.034
Abstract: Current vascularization strategies for Tissue Engineering constructs, in particular cell sheet-based, are limited by time-consuming and expensive endothelial cell isolation and/or by the complexity of using extrinsic growth factors. Herein, we propose an alternative strategy… read more here.
Keywords: cell sheets; vascular fraction; cell sheet; cell ... See more keywords
Thermoresponsive poly(glycidyl ether) brushes on gold: Surface engineering parameters and their implication for cell sheet fabrication.
Sign Up to like & getrecommendations! Published in 2017 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2017.06.029
Abstract: Thermoresponsive polymer coatings, optimized for cell adhesion and thermally-triggered cell detachment, allow the fabrication of confluent cell sheets with intact extracellular matrix. However, rational design guidelines for such coatings are rare, since temperature-triggered cell adhesion… read more here.
Keywords: engineering; poly glycidyl; glycidyl ether; cell sheet ... See more keywords
Construction of vascularized tissue-engineered bone with a double-cell sheet complex.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.07.024
Abstract: A double-cell sheet (DCS) complex composed of an osteogenic cell sheet and a vascular endothelial cell sheet with osteogenesis and blood vessel formation potential was developed in this study. The osteogenic and vascular endothelial cell… read more here.
Keywords: dcs; blood vessel; vessel formation; cell sheet ... See more keywords