Inferring transcriptional bursting kinetics from single-cell snapshot data using a generalized telegraph model
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DOI: 10.1098/rsos.221057
Abstract: Motivation Gene expression has inherent stochasticity resulting from transcription’s burst manners. Single-cell snapshot data can be exploited to rigorously infer transcriptional burst kinetics, using mathematical models as blueprints. The classical telegraph model (CTM) has been… read more here.
Keywords: bursting; cell snapshot; transcriptional bursting; burst ... See more keywords