High‐Precision 3D Bio‐Dot Printing to Improve Paracrine Interaction between Multiple Types of Cell Spheroids
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202005324
Abstract: Cell–cell interaction accounts for one of the most influential factors affecting the viability and functionality of cell‐based tissue models. In this respect, various methods capable of producing micro‐patterns with cell spheroids are introduced to simultaneously… read more here.
Keywords: bio dot; high precision; cell spheroids; interaction ... See more keywords
3D Stem Cell Spheroids with 2D Hetero‐Nanostructures for In Vivo Osteogenic and Immunologic Modulated Bone Repair
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202303772
Abstract: 3D stem cell spheroids have immense potential for various tissue engineering applications. However, current spheroid fabrication techniques encounter cell viability issues due to limited oxygen access for cells trapped within the core, as well as… read more here.
Keywords: cell spheroids; stem cell; bone repair; cell ... See more keywords
Detection of lncRNA by LNA-Based In Situ Hybridization in Paraffin-Embedded Cancer Cell Spheroids.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1581-2_8
Abstract: Cancer cell spheroids are considered important preclinical tools to evaluate the efficacy of new drugs. In cancer cell spheroids, the cells assemble and grow in 3D structures with cell contact interactions that are partly impermeable,… read more here.
Keywords: based situ; cell spheroids; cancer cell; cell ... See more keywords
Cell membrane engineering with synthetic materials: Applications in cell spheroids, cellular glues and microtissue formation.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.04.013
Abstract: Biologically inspired materials with tunable bio- and physicochemical properties provide an essential framework to actively control and support cellular behavior. Cell membrane remodeling approaches benefit from the advances in polymer science and bioconjugation methods, which… read more here.
Keywords: cell; membrane engineering; cell membrane; cell spheroids ... See more keywords
“All-in-one” zwitterionic granular hydrogel bioink for stem cell spheroids production and 3D bioprinting
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2021.132713
Abstract: Abstract Based on “bottom-up” strategy, cell-laden 3D bioprinting is an important process of fabricating sophisticated biomimetic structures. Stem cell spheroids possess better biological properties and are advanced as printing units. However, efficient and convenient preparation,… read more here.
Keywords: hydrogel; composite granular; cell spheroids; granular hydrogel ... See more keywords
Systematic Analysis of Different Cell Spheroids with a Microfluidic Device Using Scanning Electrochemical Microscopy and Gene Expression Profiling.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b00376
Abstract: The 3D cell spheroid is an emerging tool that allows better recapitulating of in vivo scenarios with multiple factors such as tissue-like morphology and membrane protein expression that intimately coordinates with enzyme activity, thus providing… read more here.
Keywords: cell spheroids; microscopy; gene expression; cell ... See more keywords
Three-Dimensional Microstructured Poly(vinyl alcohol) Hydrogel Platform for the Controlled Formation of Multicellular Cell Spheroids.
Sign Up to like & getrecommendations! Published in 2018 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.7b01345
Abstract: Three-dimensional (3D) multicellular cell spheroids (MCSs) are excellent in vitro cell models, in which, e.g., the in vivo cell-cell interaction processes are much better mimicked than in conventional two-dimensional (2D) cell layers. However, the difficulties… read more here.
Keywords: three dimensional; cell spheroids; vinyl alcohol; multicellular cell ... See more keywords
Cryopreservation of Liver-Cell Spheroids with Macromolecular Cryoprotectants
Sign Up to like & getrecommendations! Published in 2023 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.2c18288
Abstract: Spheroids are a powerful tool for basic research and to reduce or replace in vivo (animal) studies but are not routinely banked nor shared. Here, we report the successful cryopreservation of hepatocyte spheroids using macromolecular… read more here.
Keywords: cell; cryopreservation liver; spheroids macromolecular; liver cell ... See more keywords
Are 3D Tumor Cell Spheroids a Utile System for the In Vitro Evaluation of Diagnostic Radiotracers?
Sign Up to like & getrecommendations! Published in 2024 at "ACS Omega"
DOI: 10.1021/acsomega.4c08214
Abstract: By possibly bridging the gap between 2D in vitro cell assays and in vivo applications, tumor cell spheroid cultures offer promising avenues for advancing innovation in nuclear medicine. Regarding the in vitro evaluation of therapeutic… read more here.
Keywords: cell spheroids; tumor cell; evaluation diagnostic; cell ... See more keywords
Design and manufacture of 3D cell culture plate for mass production of cell-spheroids
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-50186-0
Abstract: A 3D cell culture is preferred to 2D cell culture since it allows cells to grow in all directions in vitro, similar to how they would in vivo. 3D cell culture plates currently used in… read more here.
Keywords: cell culture; cell; cell spheroids; culture plate ... See more keywords
Tumor cell directed migration based on 3D printed microfilament structure
Sign Up to like & getrecommendations! Published in 2025 at "Chinese Physics B"
DOI: 10.1088/1674-1056/ade424
Abstract: Three-dimensional (3D) cell spheroids, generated utilizing the self-organizing properties of mammalian cells, exhibit significant advantages and hold important value in simulating tissue complexity. However, they still encounter numerous limitations, including the absence of spatial anisotropy… read more here.
Keywords: cell spheroids; structure; directed migration; culture ... See more keywords