High‐Precision 3D Bio‐Dot Printing to Improve Paracrine Interaction between Multiple Types of Cell Spheroids
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202005324
Abstract: Cell–cell interaction accounts for one of the most influential factors affecting the viability and functionality of cell‐based tissue models. In this respect, various methods capable of producing micro‐patterns with cell spheroids are introduced to simultaneously… read more here.
Keywords: bio dot; high precision; cell spheroids; interaction ... See more keywords
Detection of lncRNA by LNA-Based In Situ Hybridization in Paraffin-Embedded Cancer Cell Spheroids.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1581-2_8
Abstract: Cancer cell spheroids are considered important preclinical tools to evaluate the efficacy of new drugs. In cancer cell spheroids, the cells assemble and grow in 3D structures with cell contact interactions that are partly impermeable,… read more here.
Keywords: based situ; cell spheroids; cancer cell; cell ... See more keywords
Cell membrane engineering with synthetic materials: Applications in cell spheroids, cellular glues and microtissue formation.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.04.013
Abstract: Biologically inspired materials with tunable bio- and physicochemical properties provide an essential framework to actively control and support cellular behavior. Cell membrane remodeling approaches benefit from the advances in polymer science and bioconjugation methods, which… read more here.
Keywords: cell; membrane engineering; cell membrane; cell spheroids ... See more keywords
“All-in-one” zwitterionic granular hydrogel bioink for stem cell spheroids production and 3D bioprinting
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2021.132713
Abstract: Abstract Based on “bottom-up” strategy, cell-laden 3D bioprinting is an important process of fabricating sophisticated biomimetic structures. Stem cell spheroids possess better biological properties and are advanced as printing units. However, efficient and convenient preparation,… read more here.
Keywords: hydrogel; composite granular; cell spheroids; granular hydrogel ... See more keywords
Systematic Analysis of Different Cell Spheroids with a Microfluidic Device Using Scanning Electrochemical Microscopy and Gene Expression Profiling.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b00376
Abstract: The 3D cell spheroid is an emerging tool that allows better recapitulating of in vivo scenarios with multiple factors such as tissue-like morphology and membrane protein expression that intimately coordinates with enzyme activity, thus providing… read more here.
Keywords: cell spheroids; microscopy; gene expression; cell ... See more keywords
Three-Dimensional Microstructured Poly(vinyl alcohol) Hydrogel Platform for the Controlled Formation of Multicellular Cell Spheroids.
Sign Up to like & getrecommendations! Published in 2018 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.7b01345
Abstract: Three-dimensional (3D) multicellular cell spheroids (MCSs) are excellent in vitro cell models, in which, e.g., the in vivo cell-cell interaction processes are much better mimicked than in conventional two-dimensional (2D) cell layers. However, the difficulties… read more here.
Keywords: three dimensional; cell spheroids; vinyl alcohol; multicellular cell ... See more keywords
Cryopreservation of Liver-Cell Spheroids with Macromolecular Cryoprotectants
Sign Up to like & getrecommendations! Published in 2023 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.2c18288
Abstract: Spheroids are a powerful tool for basic research and to reduce or replace in vivo (animal) studies but are not routinely banked nor shared. Here, we report the successful cryopreservation of hepatocyte spheroids using macromolecular… read more here.
Keywords: cell; cryopreservation liver; spheroids macromolecular; liver cell ... See more keywords
Design and manufacture of 3D cell culture plate for mass production of cell-spheroids
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-50186-0
Abstract: A 3D cell culture is preferred to 2D cell culture since it allows cells to grow in all directions in vitro, similar to how they would in vivo. 3D cell culture plates currently used in… read more here.
Keywords: cell culture; cell; cell spheroids; culture plate ... See more keywords
Magnetism-controlled assembly of composite stem cell spheroids for the biofabrication of contraction-modulatory 3D tissue.
Sign Up to like & getrecommendations! Published in 2021 at "Biofabrication"
DOI: 10.1088/1758-5090/ac318b
Abstract: Biofabrication of organ-like engineered 3D tissue through the assembly of magnetized 3D multi-cellular spheroids has been recently investigated in tissue engineering. However, the cytotoxicity of magnetic nanoparticles (MNPs) and contraction-induced structural deformation of the constructs… read more here.
Keywords: cell spheroids; composite stem; tissue; stem cell ... See more keywords
Cell spheroids culture array with modifiable chemical gradients
Sign Up to like & getrecommendations! Published in 2023 at "Cell Proliferation"
DOI: 10.1111/cpr.13473
Abstract: Cancer cell spheroids have been shown to mimic in vivo tumour microenvironment and are therefore suitable for in vitro drug screening. Microfluidic technology can provide conveniences for spheroid assays such as high‐throughput, simplifying manual operation… read more here.
Keywords: array modifiable; cell; culture array; spheroids culture ... See more keywords
Rapid Production and Recovery of Cell Spheroids by Automated Droplet Microfluidics
Sign Up to like & getrecommendations! Published in 2019 at "SLAS Technology"
DOI: 10.1177/2472630319877376
Abstract: The future of the life sciences is linked to automation and microfluidics. As robots start working side by side with scientists, robotic automation of microfluidics in general, and droplet microfluidics in particular, will significantly extend… read more here.
Keywords: recovery; production; cell spheroids; cell ... See more keywords