Quantitative Correlation of Nanotopography with Cell Spreading via Focal Adhesions Using Adipose‐Derived Stem Cells
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DOI: 10.1002/adbi.202000092
Abstract: Nanotopography mimicking extracellular environments reportedly impact cell morphological changes; however, elucidating this relationship has been challenging. To control cellular responses using nanostructures, in this study, the quantitative relationship between nanotopography and cell spreading mediated by… read more here.
Keywords: cell spreading; area; nanotopography cell; focal adhesions ... See more keywords
Integrin Catch Bond Kinetics Mediate Mechanosensing during Cell Spreading
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DOI: 10.1016/j.bpj.2016.11.189
Abstract: Cell spreading and polarization are morphogenetic responses to extracellular matrix adhesion. Cultured fibroblasts polarize when plated on rigid, but not compliant substrates. In this study, we demonstrate that fibroblasts have increased spread area on compliant… read more here.
Keywords: bond kinetics; integrin catch; catch bond; cell spreading ... See more keywords
A Dynamic Biochemomechanical Model of Geometry-Confined Cell Spreading.
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DOI: 10.1016/j.bpj.2017.04.044
Abstract: Cell spreading is involved in many physiological and pathological processes. The spreading behavior of a cell significantly depends on its microenvironment, but the biochemomechanical mechanisms of geometry-confined cell spreading remain unclear. A dynamic model is… read more here.
Keywords: cell spreading; confined cell; geometry confined; model ... See more keywords
Physics and Physiology of Cell Spreading in Two and Three Dimensions.
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DOI: 10.1152/physiol.00020.2021
Abstract: Cells spread on surfaces and within three-dimensional (3-D) matrixes as they grow, divide, and move. Both chemical and physical signals orchestrate spreading during normal development, wound healing, and pathological states such as fibrosis and tumor… read more here.
Keywords: physiology cell; spreading two; physics; physiology ... See more keywords
Human Salivary Histatin-1 Promotes Osteogenic Cell Spreading on Both Bio-Inert Substrates and Titanium SLA Surfaces
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.584410
Abstract: Promoting cell spreading is crucial to enhance bone healing and implant osteointegration. In this study, we investigated the stimulatory effect of human salivary histatin-1 (Hst-1) on the spreading of osteogenic cells in vitro as well… read more here.
Keywords: human salivary; bio inert; hst1; cell spreading ... See more keywords
CK2β Is a Gatekeeper of Focal Adhesions Regulating Cell Spreading
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.900947
Abstract: CK2 is a hetero-tetrameric serine/threonine protein kinase made up of two CK2α/αʹ catalytic subunits and two CK2β regulatory subunits. The free CK2α subunit and the tetrameric holoenzyme have distinct substrate specificity profiles, suggesting that the… read more here.
Keywords: cell; ck2; cell spreading; ck2 gatekeeper ... See more keywords