Gamblers: An Antibiotic-Induced Evolvable Cell Subpopulation Differentiated by Reactive-Oxygen-Induced General Stress Response.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular cell"
DOI: 10.1016/j.molcel.2019.02.037
Abstract: Antibiotics can induce mutations that cause antibiotic resistance. Yet, despite their importance, mechanisms of antibiotic-promoted mutagenesis remain elusive. We report that the fluoroquinolone antibiotic ciprofloxacin (cipro) induces mutations by triggering transient differentiation of a mutant-generating… read more here.
Keywords: response; subpopulation; cell subpopulation; reactive oxygen ... See more keywords
Acute cellular rejection in small-bowel transplantation impairs NCR+ innate lymphoid cell subpopulation 3/interleukin 22 axis.
Sign Up to like & getrecommendations! Published in 2020 at "Transplant immunology"
DOI: 10.1016/j.trim.2020.101288
Abstract: Acute cellular rejection (ACR) remains as one of the main causes of graft loss and death in intestinal transplant (ITx) patients. ACR promotes intestinal injury, disruption of the mucosal barrier, bacterial translocation, and organ dysfunction.… read more here.
Keywords: acute cellular; cellular rejection; cell subpopulation; innate lymphoid ... See more keywords
Darwinian selection within an individual or somatic selection: facts and models
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Cell Biology"
DOI: 10.1093/jmcb/mjz014
Abstract: There are known cases where a cell subpopulation bearing a selective advantage tends to or eventually replaces another cell subpopulation within an organism. This process is supposed to underlie the purging of the most frequent… read more here.
Keywords: darwinian selection; selection within; somatic selection; selection ... See more keywords