Articles with "cell subpopulations" as a keyword



Analysis of FOXP3+ regulatory T cell subpopulations in peripheral blood and tissue of patients with systemic lupus erythematosus

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Published in 2017 at "Immunologic Research"

DOI: 10.1007/s12026-017-8904-4

Abstract: Regulatory T cells (Tregs) are critical mediators of immune tolerance, yet their involvement in the autoimmune disease systemic lupus erythematosus (SLE) is incompletely understood. We analyzed CD4+ T cell subpopulations with Treg-related phenotypes and their… read more here.

Keywords: cd4 cd25; foxp3; cell subpopulations; cell ... See more keywords

Unique natural killer cell subpopulations are associated with exacerbation risk in chronic obstructive pulmonary disease

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Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-58326-7

Abstract: Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death worldwide. COPD is frequently punctuated by acute exacerbations that are precipitated primarily by infections, which increase both morbidity and mortality and inflates healthcare… read more here.

Keywords: chronic obstructive; obstructive pulmonary; copd; cell subpopulations ... See more keywords

Branched immunochip-integrated pairwise barcoding amplification exploring the spatial proximity of two post-translational modifications in distinct cell subpopulations.

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Published in 2022 at "Chemical communications"

DOI: 10.1039/d2cc03833a

Abstract: Investigating the spatial information of post-translational modifications (PTMs) in distinct cell subpopulations represents a new direction toward single-cell analysis. The specific capture of cell populations combined with PTM spatial proximity visualization making it practically challenging.… read more here.

Keywords: cell; cell subpopulations; translational modifications; distinct cell ... See more keywords

Single Cell RNA‐Seq Identifies Cell Subpopulations Contributing to Idiopathic Pulmonary Fibrosis in Humans

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Published in 2025 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.70402

Abstract: The cell populations, particularly subpopulations, involved in the onset and progression of idiopathic pulmonary fibrosis (IPF) remain incompletely understood. This study employed single‐cell RNA‐seq to identify cell populations and subpopulations with significantly altered proportions in… read more here.

Keywords: idiopathic pulmonary; cell populations; single cell; cell subpopulations ... See more keywords

Multiplexed glycan immunofluorescence identification of pancreatic cancer cell subpopulations in both tumor and blood samples

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Published in 2025 at "Science Advances"

DOI: 10.1126/sciadv.adt0029

Abstract: Pancreatic ductal adenocarcinoma (PDAC) tumor heterogeneity impedes the development of biomarker assays for early disease detection. We hypothesized that PDAC cell subpopulations could be identified by aberrant glycan signatures in both tumor tissue and blood… read more here.

Keywords: glycan immunofluorescence; cell subpopulations; blood; blood samples ... See more keywords

Atlas of the HIV-1 Reservoir in Peripheral CD4 T Cells of Individuals on Successful Antiretroviral Therapy

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Published in 2021 at "mBio"

DOI: 10.1128/mbio.03078-21

Abstract: The main barrier for HIV-1 cure is the presence of latently infected CD4+ T cells. Although various cell subpopulations have been identified as major HIV-1 reservoir cells, the relative contribution of infected CD4 subpopulations in… read more here.

Keywords: hiv; cell subpopulations; cd4; hiv reservoir ... See more keywords

Long-Term GAD-alum Treatment Effect on Different T-Cell Subpopulations in Healthy Children Positive for Multiple Beta Cell Autoantibodies

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Published in 2022 at "Journal of Immunology Research"

DOI: 10.1155/2022/3532685

Abstract: Objective The objective of this study was to explore whether recombinant GAD65 conjugated hydroxide (GAD-alum) treatment affected peripheral blood T-cell subpopulations in healthy children with multiple beta cell autoantibodies. Method The Diabetes Prevention–Immune Tolerance 2… read more here.

Keywords: cell; cell subpopulations; gad alum; alum treatment ... See more keywords

Abstract 865: Single-cell sequencing identification of malignant cell subpopulations linked to recurrence in hepatocellular carcinoma

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Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.am2024-865

Abstract: Introduction: Hepatocellular Carcinoma (HCC) is a highly malignant and challenging-to-treat tumor, with early recurrence affecting up to 35-50% of patients within two years after surgery, significantly impacting prognosis. Identifying high-risk patients for recurrence is critical… read more here.

Keywords: single cell; cell subpopulations; hepatocellular carcinoma; cell ... See more keywords

Sequencing of cancer cell subpopulations identifies micrometastases in a bladder cancer patient

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.17312

Abstract: Purpose Pathologic staging of bladder cancer patients remains a challenge. Standard-of-care histology exhibits limited sensitivity in detection of micrometastases, which can increase risk of cancer progression and delay potential adjuvant therapies. Here, we sought to… read more here.

Keywords: bladder cancer; cell subpopulations; cancer cell; cancer ... See more keywords

Phenotypic and Functional Analysis of Human NK Cell Subpopulations According to the Expression of FcεRIγ and NKG2C

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Published in 2019 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2019.02865

Abstract: Human memory-like NK cells are commonly defined by either a lack of FcεRIγ or gain of NKG2C expression. Here, we investigated the heterogeneity of human CD56dim NK cell subpopulations according to the expression of FcεRIγ… read more here.

Keywords: subpopulations according; nkg2c cells; expression; cell subpopulations ... See more keywords
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Natural Killer Cell Subpopulations and Inhibitory Receptor Dynamics in Myelodysplastic Syndromes and Acute Myeloid Leukemia

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.665541

Abstract: Natural killer (NK) cells are key innate immunity effectors that play a major role in malignant cell destruction. Based on expression patterns of CD16, CD56, CD57, and CD94, three distinct NK cell maturation stages have… read more here.

Keywords: cell; natural killer; cell subpopulations; receptor ... See more keywords