Clinical significance of stratifying prostate cancer patients through specific circulating genes
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13805
Abstract: Patient stratification remains a challenge for optimal treatment of prostate cancer (PCa). This clinical heterogeneity implies intra‐tumoural heterogeneity, with different prostate epithelial cell subtypes not all targeted by current treatments. We reported that such cell… read more here.
Keywords: significance stratifying; cancer; clinical significance; stratifying prostate ... See more keywords
Distinct Side Population Cell Subtypes Have Different Stemness Levels in Human Ovarian Cancer Cells
Sign Up to like & getrecommendations! Published in 2021 at "Current Medical Science"
DOI: 10.1007/s11596-021-2327-0
Abstract: The stemness of different side population (SP) cell subtypes in ovarian cancer cells was studied, and the heterogeneity of ovarian cancer stem cells was analyzed. The cisplatin-resistant human serous ovarian cancer cell line C13 was… read more here.
Keywords: side population; cell subtypes; ovarian cancer; cancer cells ... See more keywords
Evaluation of γ-H2AX foci distribution among different peripheral blood mononucleated cell subtypes.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of radiation biology"
DOI: 10.1080/09553002.2023.2187480
Abstract: INTRODUCTION The detection of γ-H2AX foci in peripheral blood mononucleated cells (PBMCs) has been incorporated as an early assay for biological dosimetry. However, overdispersion in the γ-H2AX foci distribution is generally reported. In a previous… read more here.
Keywords: cell; cell subtypes; foci distribution; h2ax foci ... See more keywords
Profiling peripheral B-cell subtypes most predictive for cardiac allograft rejection
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DOI: 10.1093/ehjci/ehaa946.1107
Abstract: B-cells have been strongly implicated in cardiac allograft rejection (CAR). Recently, however, the CTOT-11 trial showed that depleting mature CD20+ B-cells did not reduce rates of rejection in cardiac allograft recipients and unexpectedly increased the… read more here.
Keywords: cell subtypes; cardiac allograft; rejection; cell ... See more keywords
A combination of the activation marker CD86 and the immune checkpoint marker B and T lymphocyte attenuator (BTLA) indicates a putative permissive activation state of B cell subtypes in healthy blood donors independent of age and sex
Sign Up to like & getrecommendations! Published in 2020 at "BMC Immunology"
DOI: 10.1186/s12865-020-00343-2
Abstract: Background The use of anti-B cell based therapies in immune-mediated diseases targeting general B cell markers or molecules important for B cell function has increased the clinical needs of monitoring B cell subpopulations. Results We… read more here.
Keywords: btla; cell subtypes; cd86; expression ... See more keywords
8066 Compensatory Signatures of Islet Cells That Protect Obese Humans From Diabetes
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvae163.712
Abstract: Abstract Disclosure: H. Kim: None. Y. Li: None. H. Zhu: None. K. El Jellas: None. N. Shukla: None. Z. Ren: None. K. Fukuda: None. M. Chen: None. R. Kulkarni: Advisory Board Member; Self; Novo Nordisk,… read more here.
Keywords: protect obese; none; stellate cells; obese humans ... See more keywords
Characterization of post-vaccination SARS-CoV-2 T cell subtypes in patients with different hematologic malignancies and treatments
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1087996
Abstract: Background To evaluate the benefits of SARS-CoV-2 vaccination in cancer patients it is relevant to understand the adaptive immune response elicited after vaccination. Patients affected by hematologic malignancies are frequently immune-compromised and show a decreased… read more here.
Keywords: cell subtypes; immune response; sars cov; vaccination ... See more keywords
Immune Cell Subtypes and Cytokines in Lung Tumor Microenvironment: Influence of COPD
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DOI: 10.3390/cancers12051217
Abstract: Background: The immune microenvironment plays a role in tumorigenesis. Chronic Obstructive Pulmonary Disease (COPD) is an independent risk factor for lung cancer (LC). We hypothesized that immune profile characterized by T regulatory (Treg), natural killer… read more here.
Keywords: immune cell; cell subtypes; copd; lung tumor ... See more keywords
The Complex Dysregulations of CD4 T Cell Subtypes in HIV Infection
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25147512
Abstract: Human immunodeficiency virus (HIV) infection remains an important global public health problem. About 40 million people are infected with HIV, and this infection caused about 630,000 deaths in 2022. The hallmark of HIV infection is… read more here.
Keywords: cd4 cell; infection; cell subtypes; hiv infection ... See more keywords