Cell surface expression of human RP105 depends on N‐glycosylation of MD‐1
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14452
Abstract: For its cell surface expression, radioprotective 105 (RP105) – an orphan Toll‐like receptor – must form a complex with a soluble glycoprotein called myeloid differentiation 1 (MD‐1). The number of RP105‐negative cells is significantly increased… read more here.
Keywords: cell surface; surface expression; rp105;
RAS nanoclusters are cell surface transducers that convert extracellular stimuli to intracellular signalling
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14569
Abstract: Mutations of rat sarcoma virus (RAS) oncogenes (HRAS, KRAS and NRAS) can contribute to the development of cancers and genetic disorders (RASopathies). The spatiotemporal organization of RAS is an important property that warrants further investigation.… read more here.
Keywords: stimuli intracellular; transducers convert; cell surface; extracellular stimuli ... See more keywords
The invariant chain CD74 protein is a cell surface binding partner of TIMP-1 in breast cancer cells.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13436
Abstract: Tissue inhibitor of metalloproteinases-1 (TIMP-1) regulates the proteolytic activity of matrix metalloproteinases (MMPs), playing an important role in the homeostasis of the extracellular matrix. Beyond its well-known role in tissue maintenance, TIMP-1 has been associated… read more here.
Keywords: cell surface; breast cancer; timp; cancer cells ... See more keywords
Multi-Catcher Polymers Regulate the Nucleolin Cluster on the Cell Surface for Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300102
Abstract: Cell signal transduction mediated by cell surface ligand-receptor is crucial for regulating cell behavior. The oligomerization or hetero-aggregation of the membrane receptor driven by the ligand realizes the rearrangement of apoptotic signals, providing a new… read more here.
Keywords: cell; multi catcher; cell surface; surface ... See more keywords
Membrane‐Fusion‐Mediated Multiplex Engineering of Tumor Cell Surface Glycans for Enhanced NK Cell Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202206989
Abstract: Natural killer (NK) cell therapies show potential for tumor treatment but are immunologically resisted by the overexpressed immunosuppressing tumor cell surface glycans. To reverse this glycan‐mediated immunosuppression, the surface NK‐inhibitory glycan expressions need to be… read more here.
Keywords: cell; cell surface; membrane; tumor ... See more keywords
Materials for Cell Surface Engineering.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202210059
Abstract: Cell therapies are emerging as a promising new therapeutic modality in medicine, generating effective treatments of previously incurable diseases. Clinical success of cell therapies has energized the field of cellular engineering, spurring further exploration of… read more here.
Keywords: cell; cell surface; surface engineering; engineering ... See more keywords
Cell‐surface exposure of a hybrid 3‐cohesin scaffoldin allowing the functionalization of Escherichia coli envelope
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27242
Abstract: Cellulosomes are large plant cell wall degrading complexes secreted by some anaerobic bacteria. They are typically composed of a major scaffolding protein containing multiple receptors called cohesins, which tightly anchor a small complementary module termed… read more here.
Keywords: escherichia coli; module; surface; surface exposure ... See more keywords
Flow cytometric detection of most proteins in the cell surface proteome is unaffected by trypsin treatment
Sign Up to like & getrecommendations! Published in 2018 at "Cytometry Part A"
DOI: 10.1002/cyto.a.23525
Abstract: Flow cytometry is often performed on adherent cells or solid tissues that have been released from their growth substrate or disaggregated by enzymatic digestion. Although detection of strongly expressed cell surface proteins following such procedures… read more here.
Keywords: detection; treatment; trypsin; trypsin treatment ... See more keywords
An overview on enrichment methods for cell surface proteome profiling.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of separation science"
DOI: 10.1002/jssc.201900700
Abstract: Cell surface proteins are essential for many important biological processes, including cell-cell interactions, signal transduction, and molecular transportation. With the characteristics of low abundance, high hydrophobicity, and high heterogeneity, it is difficult to get a… read more here.
Keywords: cell surface; surface proteome; surface; enrichment methods ... See more keywords
Effects of Various Cell Surface Engineering Reactions on the Biological Behavior of Mammalian Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200379
Abstract: Cell surface engineering technologies can regulate cell function and behavior by modifying the cell surface. Previous studies have mainly focused on investigating the effects of cell surface engineering reactions and materials on cell activity. However,… read more here.
Keywords: cell; modification; cell surface; surface engineering ... See more keywords
Symposium Summaries
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24151
Abstract: membrane, but rather undergoes constitutive internalization from the cell surface (1). Indeed, the endocytic kinetics for CFTR are remarkably fast, approaching that of nutrient receptors such as the LDL and transferrin receptors (2-4). Although there… read more here.
Keywords: cftr; recycling pathway; f508 cftr; cell surface ... See more keywords