Abstract 3687: Disruption of nucleotide homeostasis confers cancer cell susceptibility to oxidative phosphorylation inhibition independently of energy depletion
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DOI: 10.1158/1538-7445.am2023-3687
Abstract: Cancer metabolism is highly heterogenous and flexible with the Warburg effect or oxidative phosphorylation (OXPHOS) prevailing in a cancer type- and context-dependent manner. Past studies have demonstrated that targeting OXPHOS robustly inhibits glycolysis-deficient cancer cell… read more here.
Keywords: cell; oxphos inhibition; cancer cell; cell susceptibility ... See more keywords