Ovalbumin and Poly(i:c) Encapsulated Dendritic Cell‐Targeted Nanoparticles for Immune Activation in the Small Intestinal Lymphatic System
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DOI: 10.1002/adhm.202200909
Abstract: Here, antigen and adjuvant encapsulated dendritic cell‐targeted nanoparticles for immune activation in the small intestinal lymphatic system to inhibit melanoma development are described. This strategy is demonstrated using chondroitin sulfate‐coated nanoparticles (OPGMN) grafted with glycocholic… read more here.
Keywords: cell; cell targeted; nanoparticles immune; dendritic cell ... See more keywords
Possibility of cancer-stem-cell-targeted radioimmunotherapy for acute myelogenous leukemia using 211At-CXCR4 monoclonal antibody
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DOI: 10.1038/s41598-020-63557-9
Abstract: To explore stem-cell-targeted radioimmunotherapy with α-particles in acute myelogenous leukemia (AML), pharmacokinetics and dosimetry of the 211At-labeled anti-C-X-C chemokine receptor type 4 monoclonal antibody (211At-CXCR4 mAb) were conducted using tumor xenografted mice. The biological half-life… read more here.
Keywords: 211at cxcr4; stem cell; cell targeted; targeted radioimmunotherapy ... See more keywords
Next stop in the treatment of refractory systemic lupus erythematosus: B-cell targeted combined therapy
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DOI: 10.1177/0961203320965707
Abstract: Background: Systemic lupus erythematosus (SLE) is an autoimmune condition with a wide spectrum of clinical manifestations encompassing most organs and systems. Its treatment approach includes different immunomodulatory treatments, of which B-cell targeted therapies are part… read more here.
Keywords: systemic lupus; combined therapy; lupus erythematosus; cell targeted ... See more keywords
B cell targeted therapies in inflammatory autoimmune disease of the central nervous system
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DOI: 10.3389/fimmu.2023.1129906
Abstract: Cumulative evidence along several lines indicates that B cells play an important role in the pathological course of multiple sclerosis (MS), neuromyelitisoptica spectrum disorders (NMOSD) and related CNS diseases. This has prompted extensive research in… read more here.
Keywords: cell; inflammatory autoimmune; therapies inflammatory; targeted therapies ... See more keywords
Oral Cell-Targeted Delivery Systems Constructed of Edible Materials: Advantages and Challenges
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DOI: 10.3390/molecules27227991
Abstract: Cell-targeted delivery is an advanced strategy which can effectively solve health problems. However, the presence of synthetic materials in delivery systems may trigger side effects. Therefore, it is necessary to develop cell-targeted delivery systems with… read more here.
Keywords: edible materials; cell targeted; delivery systems; delivery ... See more keywords