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   Articles with "cell targeting" as a keyword



Site‐Specific Antibody Assembly on Nanoparticles via a Versatile Coating Method for Improved Cell Targeting

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recommendations! Published in 2023 at "Advanced Science"

DOI: 10.1002/advs.202206546

Abstract: Antibody‐nanoparticle conjugates are promising candidates for precision medicine. However, developing a controllable method for conjugating antibodies to nanoparticles without compromising the antibody activity represents a critical challenge. Here, a facile and generalizable film‐coating method is… read more here.

Keywords: cell targeting; nanoparticles via; method; coating method ... See more keywords

d-Fructose-Decorated Poly(ethylene imine) for Human Breast Cancer Cell Targeting.

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recommendations! Published in 2017 at "Macromolecular bioscience"

DOI: 10.1002/mabi.201600502

Abstract: The high affinity of GLUT5 transporter for d-fructose in breast cancer cells has been discussed intensely. In this contribution, high molar mass linear poly(ethylene imine) (LPEI) is functionalized with d-fructose moieties to combine the selectivity… read more here.

Keywords: breast; cell targeting; breast cancer; poly ethylene ... See more keywords

Collaborative membrane activity and receptor-dependent tumor cell targeting for precise nanoparticle delivery in CXCR4+ colorectal cancer.

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recommendations! Published in 2019 at "Acta biomaterialia"

DOI: 10.1016/j.actbio.2019.09.002

Abstract: By the appropriate selection of functional peptides and proper accommodation sites, we have generated a set of multifunctional proteins that combine selectivity for CXCR4+ cell binding and relevant endosomal escape capabilities linked to the viral… read more here.

Keywords: tumor; cell targeting; colorectal cancer; cell ... See more keywords

Endothelial Cell-Targeting, ROS-Ultrasensitive Drug/siRNA Co-Delivery Nanocomplexes Mitigate Early-Stage Neutrophil Recruitment For the Anti-Inflammatory Treatment of Myocardial Ischemia Reperfusion Injury.

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recommendations! Published in 2022 at "Acta biomaterialia"

DOI: 10.1016/j.actbio.2022.02.018

Abstract: Neutrophils serve as a key contributor to the pathophysiology of myocardial ischemia reperfusion injury (MIRI), because the unregulated activation and infiltration of neutrophils lead to overwhelming inflammation in the myocardium to cause tissue damage. Herein,… read more here.

Keywords: delivery; endothelial cell; cell targeting; sirna ... See more keywords

Synergistic effects of dendritic cell targeting and laser‐microporation on enhancing epicutaneous skin vaccination efficacy

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recommendations! Published in 2017 at "Journal of Controlled Release"

DOI: 10.1016/j.jconrel.2017.09.020

Abstract: ABSTRACT Due to its unique immunological properties, the skin is an attractive target tissue for allergen‐specific immunotherapy. In our current work, we combined a dendritic cell targeting approach with epicutaneous immunization using an ablative fractional… read more here.

Keywords: cell targeting; mannan neoglycoconjugates; laser microporation; dendritic cell ... See more keywords

Methotrexate-plasmid DNA polyplexes for cancer therapy: Characterization, cancer cell targeting ability and tuned in vitro transfection

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recommendations! Published in 2019 at "Journal of Molecular Liquids"

DOI: 10.1016/j.molliq.2019.111391

Abstract: Abstract Cell targeting is still the most auspicious task in the design/development of innovative drug and gene delivery systems for advanced biomedical applications. To evolve from conventional delivery vectors, which present several limitations, we report… read more here.

Keywords: cell targeting; plasmid dna; cancer; cancer cell ... See more keywords

Peptide-Functionalized Hydrogel Cubes for Active Tumor Cell Targeting.

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recommendations! Published in 2018 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.8b01088

Abstract: Conjugation of bioactive targeting molecules to nano- or micrometer-sized drug carriers is a pivotal strategy to improve their therapeutic efficiency. Herein, we developed pH- and redox-sensitive hydrogel particles with a surface-conjugated cancer cell targeting ligand… read more here.

Keywords: hydrogel; cell targeting; peptide functionalized; hydrogel cubes ... See more keywords

Gramicidin A-based unimolecular channel: cancer cell-targeting behavior and ion transport-induced apoptosis.

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recommendations! Published in 2021 at "Chemical communications"

DOI: 10.1039/d0cc08073j

Abstract: A series of glycoside-peptide conjugates were prepared by engineering at the N-terminus of the natural peptide gramicidin A. The conjugate containing galactose moiety formed a unimolecular transmembrane channel and mediated ion transport to induce apoptosis… read more here.

Keywords: ion transport; cell targeting; cancer cell; cancer ... See more keywords

Lupus nephritis and B-cell targeting therapy

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recommendations! Published in 2017 at "Expert Review of Clinical Immunology"

DOI: 10.1080/1744666x.2017.1366855

Abstract: ABSTRACT Introduction: Lupus Nephritis (LN) is a severe manifestation of Systemic Lupus Erythematosus (SLE) with a significant prognostic impact. Over a prolonged course, an exhaustion of treatment alternatives may occur and further therapeutic options are… read more here.

Keywords: cell targeting; lupus nephritis; nephritis cell; targeting therapy ... See more keywords

Wanted: An endothelial cell targeting atlas for nanotherapeutic delivery in allograft organs

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recommendations! Published in 2022 at "American Journal of Transplantation"

DOI: 10.1111/ajt.17050

Abstract: Despite the profound shortage of organs available for transplant in the U.S., over 5,000 donated organs were declined for use in 2020. Many of these organs were declined due to donor comorbidities or preservation injuries… read more here.

Keywords: atlas nanotherapeutic; targeting atlas; cell targeting; wanted endothelial ... See more keywords

B cell targeting in IgA nephropathy

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recommendations! Published in 2024 at "Nephrology"

DOI: 10.1111/nep.14367

Abstract: The “multi‐hit theory/4‐hit theory” pathogenesis hypothesis is widely accepted and IgA nephropathy (IgAN) is understood to be a disease originating from Hit 1, galactose deficient IgA1 (GdIgA1). The chronic repetitive activation of the complement pathway… read more here.

Keywords: targeting iga; cell targeting; iga nephropathy; gdiga1 ... See more keywords