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Published in 2022 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202207626
Abstract: Superparamagnetic iron oxide (SPIO)‐labeling of cells has been applied for magnetic resonance imaging (MRI) cell tracking for over 30 years, having resulted in a dozen or so clinical trials. SPIO nanoparticles are biodegradable and can…
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Keywords:
cell tracking;
vivo cellular;
unlabeled cells;
imaging labeled ... See more keywords
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Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201806216
Abstract: Longitudinal tracking of living cells is crucial to understanding the mechanism of action and toxicity of cell-based therapeutics. To quantify the presence of administered cells in the host tissue without sacrifice of animals, labeling of…
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Keywords:
targeted bioprobes;
lysosome targeted;
sequential cell;
bioprobes sequential ... See more keywords
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Published in 2018 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.27018
Abstract: MRI cell tracking can be used to monitor immune cells involved in the immunotherapy response, providing insight into the mechanism of action, temporal progression of tumor growth, and individual potency of therapies. To evaluate whether…
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Keywords:
response;
monitor immune;
mri cell;
cell tracking ... See more keywords
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Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.01.043
Abstract: We introduce an efficient cell tracking imaging protocol using positron emission tomography (PET). Since macrophages are known to home and accumulate in tumor tissues and atherosclerotic plaque, we design a PET imaging protocol for macrophage…
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Keywords:
macrophage cell;
mesoporous silica;
pet imaging;
cell tracking ... See more keywords
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Published in 2022 at "Chemical Reviews"
DOI: 10.1021/acs.chemrev.1c00767
Abstract: The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical application in a rational manner depends on reliable, clinically applicable methods for determining the fate and trafficking of therapeutic cells in…
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Keywords:
cell tracking;
cell;
vivo cell;
radiolabeling vivo ... See more keywords
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Published in 2020 at "ACS nano"
DOI: 10.1021/acsnano.9b08660
Abstract: Stem cell therapies are increasingly recognized as the future direction of regenerative medicine, but the biological fate of the administrated stem cells remains a major concern for clinical translation, which calls for an approach to…
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Keywords:
magnetic particle;
stem cell;
cell tracking;
particle imaging ... See more keywords
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Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-66388-w
Abstract: One of the main challenges in cell therapy for muscle diseases is to efficiently target the muscle. To address this issue and achieve better understanding of in vivo cell fate, we evaluated the relevance of…
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Keywords:
model;
cell tracking;
vivo stem;
model dmd ... See more keywords
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep44233
Abstract: Assessing the retention of cell therapies following implantation is vital and often achieved by labelling cells with 2′-[18F]-fluoro-2′-deoxy-D-glucose (18F-FDG). However, this approach is limited by local retention of cell-effluxed radiotracer. Here, in a preclinical model…
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Keywords:
cell tracking;
18f flt;
18f fdg;
cell ... See more keywords
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Published in 2018 at "Nanoscale"
DOI: 10.1039/c7nr07618e
Abstract: Superparamagnetic iron oxide nanoparticles (SPIONs) have been developed as excellent magnetic resonance imaging (MRI) contrast agents for stem cell labeling and tracking due to their biocompatibility. In this study, we designed a self-assembled peptide amphiphile…
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Keywords:
peptide modified;
self assembled;
stem cell;
cell tracking ... See more keywords
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Published in 2022 at "Fly"
DOI: 10.1080/19336934.2022.2142460
Abstract: ABSTRACT Multiscale analysis of morphogenesis requires to follow and measure in real-time the in vivo behaviour of large numbers of individual cells over long period of time. Despite recent progress, the large-scale automated tracking of…
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Keywords:
individual cells;
cell tracking;
cell;
nuclear halotag ... See more keywords
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Published in 2019 at "IEEE Access"
DOI: 10.1109/access.2019.2930539
Abstract: In recent years, cell tracking methods by detection have become more and more popular because they outperformed cell tracking methods by contour evolution in most practical cell tracking applications. Yet, the most frequently used segmentation…
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Keywords:
detection;
new approach;
cell detection;
cell ... See more keywords